"Casein Kinase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulatory subunit. Casein kinase II has been shown to phosphorylate a large number of substrates, many of which are proteins involved in the regulation of gene expression.
| Descriptor ID |
D047390
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.140.600 D12.776.476.150.600
|
| Concept/Terms |
Casein Kinase II- Casein Kinase II
- Protein Kinase CKII
- Kinase CKII, Protein
- Casein Kinase-2
- Protein Kinase CK2
- Casein Kinase 2
- Casein Kinase TS
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase II".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase II".
This graph shows the total number of publications written about "Casein Kinase II" by people in this website by year, and whether "Casein Kinase II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 2 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Casein Kinase II" by people in Profiles.
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Critical role of protein kinase CK2 in chronic myeloid leukemia cells harboring the T315I BCR::ABL1 mutation. Int J Biol Macromol. 2025 Jan; 286:138305.
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Nerve injury augments Cacna2d1 transcription via CK2-mediated phosphorylation of the histone deacetylase HDAC2 in dorsal root ganglia. J Biol Chem. 2024 Nov; 300(11):107848.
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Phosphorylation and Stabilization of PD-L1 by CK2 Suppresses Dendritic Cell Function. Cancer Res. 2022 06 06; 82(11):2185-2195.
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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells. Mol Cell. 2021 03 18; 81(6):1276-1291.e9.
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White Adipose Tissue Expansion in Multiple Symmetric Lipomatosis Is Associated with Upregulation of CK2, AKT and ERK1/2. Int J Mol Sci. 2020 Oct 26; 21(21).
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Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication. Mol Cell. 2018 11 15; 72(4):650-660.e8.
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Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex. Nucleic Acids Res. 2017 03 17; 45(5):2585-2599.
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Casein Kinase 2 Is Linked to Stress Granule Dynamics through Phosphorylation of the Stress Granule Nucleating Protein G3BP1. Mol Cell Biol. 2017 02 15; 37(4).
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Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex. Mol Cancer Res. 2017 05; 15(5):610-618.
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Genetic variants of the Wnt signaling pathway as predictors of aggressive disease and reclassification in men with early stage prostate cancer on active surveillance. Carcinogenesis. 2016 Oct; 37(10):965-971.