"Casein Kinase I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A casein kinase that was originally described as a monomeric enzyme with a molecular weight of 30-40 kDa. Several ISOENZYMES of casein kinase I have been found which are encoded by separate genes. Many of the casein kinase I isoenzymes have been shown to play distinctive roles in intracellular SIGNAL TRANSDUCTION.
| Descriptor ID |
D047389
|
| MeSH Number(s) |
D05.500.117.750 D08.811.913.696.620.682.700.140.300 D12.776.476.081.750 D12.776.476.150.299
|
| Concept/Terms |
Casein Kinase I- Casein Kinase I
- Kinase I, Casein
- Protein Kinase CKI
- Casein Kinase 1
- Kinase 1, Casein
- Protein Kinase CK1
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase I".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase I".
This graph shows the total number of publications written about "Casein Kinase I" by people in this website by year, and whether "Casein Kinase I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Casein Kinase I" by people in Profiles.
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circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment. Nat Commun. 2022 11 25; 13(1):7243.
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CircCSNK1G3 up-regulates miR-181b to promote growth and metastasis via TIMP3-mediated epithelial to mesenchymal transitions in renal cell carcinoma. J Cell Mol Med. 2022 03; 26(6):1729-1741.
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In vitro phosphorylation of von Willebrand factor by FAM20c enhances its ability to support platelet adhesion. J Thromb Haemost. 2019 06; 17(6):866-877.
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Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proc Natl Acad Sci U S A. 2017 08 22; 114(34):9098-9103.
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Endogenous casein kinase-1 modulates NMDA receptor activity of hypothalamic presympathetic neurons and sympathetic outflow in hypertension. J Physiol. 2015 Oct 01; 593(19):4439-52.
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2-Phenylamino-6-cyano-1H-benzimidazole-based isoform selective casein kinase 1 gamma (CK1?) inhibitors. Bioorg Med Chem Lett. 2012 Sep 01; 22(17):5392-5.
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MiR-155 is a liposarcoma oncogene that targets casein kinase-1a and enhances ?-catenin signaling. Cancer Res. 2012 Apr 01; 72(7):1751-62.
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Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814.
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Identification of diverse modulators of central and peripheral circadian clocks by high-throughput chemical screening. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):101-6.
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Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members. J Cell Sci. 2010 Dec 15; 123(Pt 24):4351-65.