"Aldehyde Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.
| Descriptor ID |
D000449
|
| MeSH Number(s) |
D08.811.682.047.150.700.156.500 D08.811.682.047.820.284.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde Reductase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Reductase".
This graph shows the total number of publications written about "Aldehyde Reductase" by people in this website by year, and whether "Aldehyde Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aldehyde Reductase" by people in Profiles.
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Aldose reductase promotes diet-induced obesity via induction of senescence in subcutaneous adipose tissue. Obesity (Silver Spring). 2022 08; 30(8):1647-1658.
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Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells. Cancer Res. 2018 04 01; 78(7):1604-1618.
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Aldose reductase modulates acute activation of mesenchymal markers via the ?-catenin pathway during cardiac ischemia-reperfusion. PLoS One. 2017; 12(11):e0188981.
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AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program. J Exp Med. 2017 04 03; 214(4):1065-1079.
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Caveolin 1 Modulates Aldosterone-Mediated Pathways of Glucose and Lipid Homeostasis. J Am Heart Assoc. 2016 09 28; 5(10).
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Prevention of allergic rhinitis by aldose reductase inhibition in a murine model. Inflamm Allergy Drug Targets. 2013 Jun; 12(3):178-86.
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Aldose reductase modulates cardiac glycogen synthase kinase-3? phosphorylation during ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2012 Aug 01; 303(3):H297-308.
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Candidate locus analysis for PHACE syndrome. Am J Med Genet A. 2012 Jun; 158A(6):1363-7.
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Aldose reductase inhibition suppresses the expression of Th2 cytokines and airway inflammation in ovalbumin-induced asthma in mice. J Immunol. 2009 Oct 01; 183(7):4723-32.
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Functional coupling between the Kv1.1 channel and aldoketoreductase Kvbeta1. J Biol Chem. 2008 Mar 28; 283(13):8634-42.