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USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.
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USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.
USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nat Immunol. 2014 Jun; 15(6):562-70.
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PubMed
subject areas
Adoptive Transfer
Animals
Apoptosis
Cell Differentiation
Cell Line, Tumor
Cell Survival
HCT116 Cells
Humans
Leupeptins
Listeria monocytogenes
Listeriosis
Lymphocyte Activation
Melanoma, Experimental
Mice
Mice, Inbred C57BL
Mice, Knockout
NFATC Transcription Factors
Proto-Oncogene Proteins c-mdm2
Th1 Cells
Tumor Escape
Tumor Suppressor Protein p53
Ubiquitination
Ubiquitin-Specific Proteases
authors with profiles
STEPHEN E ULLRICH
GUILLERMINA LOZANO
STEPHANIE S WATOWICH
CHENGMING ZHU
SHAO-CONG SUN
XIAOFEI ZHOU