Header Logo

MARIO ESCOBAR

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address1504 TAUB LOOP
Houston, TX 77030
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Escobar M, Malik SA, Srinivasa MA, Mendez-Sosa MA, Miller JM, Lydon SL, Luong SN, Mathew PR, Abouleisa RRE, Chakravarty S, Pathan S, Mohamed TMA, Ghanta RK, Hilton IB. CRISPR-Cas-based activation of PPARGC1A boosts endogenous mitochondria and enhances cardiac function after myocardial infarction. Mol Ther. 2026 Jun 03; 34(6):3320-3333. PMID: 41806830; PMCID: PMC13045639.
      Citations:    Fields:    
    2. Srinivasa MA, Escobar M. CRISPR-based Transcriptional Regulation: Technologies, Applications, and Future Directions. DNA (Basel). 2025 Dec; 5(4):57. PMID: 41877893; PMCID: PMC13007986.
      Citations: 1     
    3. Li J, Liu S, Kim S, Goell J, Drum ZA, Flores JP, Ma AJ, Mahata B, Escobar M, Raterink A, Ahn JH, Ter?n ER, Guerra-Resendez RS, Zhou Y, Yu B, Diehl MR, Wang GG, Gustavsson AK, Phanstiel DH, Hilton IB. Biomolecular condensation of human IDRs initiates endogenous transcription via intrachromosomal looping or high-density promoter localization. Nucleic Acids Res. 2025 Feb 08; 53(4). PMID: 39933697; PMCID: PMC11811730.
      Citations:    
    4. Guerra-Resendez RS, Lydon SL, Ma AJ, Bedford GC, Reed DR, Kim S, Ter?n ER, Nishiguchi T, Escobar M, DiNardo AR, Hilton IB. Characterization of Rationally Designed CRISPR/Cas9-Based DNA Methyltransferases with Distinct Methyltransferase and Gene Silencing Activities in Human Cell Lines and Primary Human T Cells. ACS Synth Biol. 2025 02 21; 14(2):384-397. PMID: 39898483; PMCID: PMC11854388.
      Citations: 2     Fields:    Translation:HumansCells
    5. Goell J, Li J, Mahata B, Ma AJ, Kim S, Shah S, Shah S, Contreras M, Misra S, Reed D, Bedford GC, Escobar M, Hilton IB. Tailoring a CRISPR/Cas-based Epigenome Editor for Programmable Chromatin Acylation and Decreased Cytotoxicity. bioRxiv. 2024 Sep 22. PMID: 39345554; PMCID: PMC11429961.
      Citations:    
    6. Mahata B, Cabrera A, Brenner DA, Guerra-Resendez RS, Li J, Goell J, Wang K, Guo Y, Escobar M, Parthasarathy AK, Szadowski H, Bedford G, Reed DR, Kim S, Hilton IB. Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control. Nat Methods. 2023 11; 20(11):1716-1728. PMID: 37813990; PMCID: PMC10630135.
      Citations:    
    7. Zhao F, Sun C, Liu Z, Cabrera A, Escobar M, Huang S, Yuan Q, Nie Q, Luo KL, Lin A, Vanegas JA, Zhu T, Hilton IB, Gao X. Multiplex Base-Editing Enables Combinatorial Epigenetic Regulation for Genome Mining of Fungal Natural Products. J Am Chem Soc. 2023 01 11; 145(1):413-421. PMID: 36542862; PMCID: PMC10162584.
      Citations:    
    8. Escobar M, Li J, Patel A, Liu S, Xu Q, Hilton IB. Quantification of Genome Editing and Transcriptional Control Capabilities Reveals Hierarchies among Diverse CRISPR/Cas Systems in Human Cells. ACS Synth Biol. 2022 10 21; 11(10):3239-3250. PMID: 36162812; PMCID: PMC9594343.
      Citations:    
    9. Wang K, Escobar M, Li J, Mahata B, Goell J, Shah S, Cluck M, Hilton IB. Systematic comparison of CRISPR-based transcriptional activators uncovers gene-regulatory features of enhancer-promoter interactions. Nucleic Acids Res. 2022 08 12; 50(14):7842-7855. PMID: 35849129; PMCID: PMC9371918.
      Citations:    
    10. Li J, Mahata B, Escobar M, Goell J, Wang K, Khemka P, Hilton IB. Programmable human histone phosphorylation and gene activation using a CRISPR/Cas9-based chromatin kinase. Nat Commun. 2021 02 09; 12(1):896. PMID: 33563994; PMCID: PMC7873277.
      Citations:    
    ESCOBAR's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (53)
    Explore
    _
    Co-Authors (6)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _