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HU CHEN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1250 MOURSUND STREET
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    Collapse Biography 
    Collapse education and training
    Baylor College of Medicine, HoustonPhD12/2020Computational biology
    UT MD Anderson Cancer Center, Houston12/2022Cancer genomics

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Matatall KA, Wathan TK, Nguyen M, Chen H, McDonald A, Qi G, Belk JA, Florez MA, Le DT, Olarinde T, Vlasschaert C, Buttigieg MM, Fan CW, Carcamo S, Cao R, Kennedy DE, Maknojia AA, Thatavarty A, Fernandez Sanchez JV, Bouzid H, Veeraragavan S, Crocker S, Goodell MA, Rodriguez A, Jaiswal S, Rauh MJ, Papapetrou EP, Marro SG, King KY. TET2-mutant myeloid cells mitigate Alzheimer's disease progression via CNS infiltration and enhanced phagocytosis in mice. Cell Stem Cell. 2025 Aug 07; 32(8):1285-1298.e8. PMID: 40609533; PMCID: PMC12233156.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Boyd SR, Chamakuri S, Trostle AJ, Chen H, Liu Z, Jian A, Wang J, Malovannaya A, Young DW. MYC-Targeting PROTACs Lead to Bimodal Degradation and N-Terminal Truncation. ACS Chem Biol. 2025 Apr 18; 20(4):896-906. PMID: 40146931.
      Citations: 1     Fields:    Translation:HumansCells
    3. Li X, Liu C, Li W, Qi G, Dai Y, Gu C, Sun Y, Zhou W, Ciliberto VC, Liang J, Kumar S U, Guan D, Hu Z, Zheng H, Liu Z, Chen H, Wan YW, Sun Z. Multi-omics delineate growth factor network underlying exercise effects in an Alzheimer's mouse model. Alzheimers Dement. 2025 Mar; 21(3):e70024. PMID: 40156268; PMCID: PMC11953571.
      Citations:    Fields:    Translation:AnimalsCells
    4. Belfort BDW, Jia JD, Garza AR, Insalaco AM, McGinnis JP, Pekarek BT, Ortiz-Guzman J, Tepe B, Chen H, aSCENT-PD Investigators, Liu Z, Arenkiel BR. Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons. Front Neurosci. 2025; 19:1531122. PMID: 40018362; PMCID: PMC11865030.
      Citations:    
    5. Bajikar SS, Zhou J, O'Hara R, Tirumala HP, Durham MA, Trostle AJ, Dias M, Shao Y, Chen H, Wang W, Yalamanchili HK, Wan YW, Banaszynski LA, Liu Z, Zoghbi HY. Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis. Neuron. 2025 Feb 05; 113(3):380-395.e8. PMID: 39689710; PMCID: PMC11802321.
      Citations: 4     Fields:    Translation:AnimalsCells
    6. Zhou J, Cattoglio C, Shao Y, Tirumala HP, Vetralla C, Bajikar SS, Li Y, Chen H, Wang Q, Wu Z, Tang B, Zahabiyon M, Bajic A, Meng X, Ferrie JJ, LaGrone A, Zhang P, Kim JJ, Tang J, Liu Z, Darzacq X, Heintz N, Tjian R, Zoghbi HY. A novel pathogenic mutation of MeCP2 impairs chromatin association independent of protein levels. Genes Dev. 2023 10 01; 37(19-20):883-900. PMID: 37890975; PMCID: PMC10691473.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    7. Zhou Z, Chen MM, Luo Y, Mojumdar K, Peng X, Chen H, Kumar SV, Akbani R, Lu Y, Liang H. Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma. Cancer Cell. 2022 11 14; 40(11):1324-1340.e8. PMID: 36332624; PMCID: PMC9669221.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Li J, Chen H, Wang Y, Chen MM, Liang H. Next-Generation Analytics for Omics Data. Cancer Cell. 2021 01 11; 39(1):3-6. PMID: 32976776; PMCID: PMC8336660.
      Citations: 7     Fields:    Translation:HumansAnimals
    9. Chen H, Li J, Wang Y, Ng PK, Tsang YH, Shaw KR, Mills GB, Liang H. Comprehensive assessment of computational algorithms in predicting cancer driver mutations. Genome Biol. 2020 02 20; 21(1):43. PMID: 32079540; PMCID: PMC7033911.
      Citations: 19     Fields:    Translation:Humans
    10. Ye Y, Hu Q, Chen H, Liang K, Yuan Y, Xiang Y, Ruan H, Zhang Z, Song A, Zhang H, Liu L, Diao L, Lou Y, Zhou B, Wang L, Zhou S, Gao J, Jonasch E, Lin SH, Xia Y, Lin C, Yang L, Mills GB, Liang H, Han L. Characterization of Hypoxia-associated Molecular Features to Aid Hypoxia-Targeted Therapy. Nat Metab. 2019 04; 1(4):431-444. PMID: 31984309; PMCID: PMC6980239.
      Citations: 50     Fields:    Translation:HumansCells
    11. Wang Y, Xu X, Maglic D, Dill MT, Mojumdar K, Ng PK, Jeong KJ, Tsang YH, Moreno D, Bhavana VH, Peng X, Ge Z, Chen H, Li J, Chen Z, Zhang H, Han L, Du D, Creighton CJ, Mills GB, Cancer Genome Atlas Research Network, Camargo F, Liang H. Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer. Cell Rep. 2018 10 30; 25(5):1304-1317.e5. PMID: 30380420; PMCID: PMC6326181.
      Citations: 115     Fields:    Translation:HumansCells
    12. Ge Z, Leighton JS, Wang Y, Peng X, Chen Z, Chen H, Sun Y, Yao F, Li J, Zhang H, Liu J, Shriver CD, Hu H, Cancer Genome Atlas Research Network, Piwnica-Worms H, Ma L, Liang H. Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types. Cell Rep. 2018 04 03; 23(1):213-226.e3. PMID: 29617661; PMCID: PMC5916807.
      Citations: 48     Fields:    Translation:HumansCells
    13. Ng PK, Li J, Jeong KJ, Shao S, Chen H, Tsang YH, Sengupta S, Wang Z, Bhavana VH, Tran R, Soewito S, Minussi DC, Moreno D, Kong K, Dogruluk T, Lu H, Tokheim C, Zhou DC, Johnson AM, Zeng J, Ip CKM, Ju Z, Wester M, Yu S, Li Y, Vellano CP, Karchin R, Ding L, Lu Y, Cheung LWT, Chen K, Shaw KR, Meric-Bernstam F, Scott KL, Yi S, Sahni N, Liang H, Mills GB, Gao J, Schultz N. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018 03 12; 33(3):450-462.e10. PMID: 29533785; PMCID: PMC5926201.
      Citations: 78     Fields:    Translation:Humans
    14. Yuan Y, Liu L, Chen H, Wang Y, Xu Y, Mao H, Li J, Mills GB, Shu Y, Li L, Liang H. Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients. Cancer Cell. 2016 05 09; 29(5):711-722. PMID: 27165743; PMCID: PMC4864951.
      Citations: 100     Fields:    Translation:HumansCells
    15. Zhang HM, Chen H, Liu W, Liu H, Gong J, Wang H, Guo AY. AnimalTFDB: a comprehensive animal transcription factor database. Nucleic Acids Res. 2012 Jan; 40(Database issue):D144-9. PMID: 22080564; PMCID: PMC3245155.
      Citations:    
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