"APOBEC-1 Deaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An APOBEC deaminase catalytic subunit of the apolipoprotein B (APOB) MESSENGER RNA (mRNA) editing enzyme complex that is involved in post-transcriptional editing of a CAA codon for GLYCINE to a UAA STOP CODON in the ApoB mRNA. It also functions in CGA (ARGININE) to UGA STOP CODON editing of NEUROFIBROMIN 1 mRNA and EPIGENETIC PROCESSES.
| Descriptor ID |
D000071479
|
| MeSH Number(s) |
D08.811.277.151.486.250.500.500
|
| Concept/Terms |
APOBEC-1 Deaminase- APOBEC-1 Deaminase
- APOBEC 1 Deaminase
- Deaminase, APOBEC-1
- ApoB mRNA Editing Catalytic Subunit
- Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide 1
- APOBEC-1
- APOBEC1 Deaminase
- Deaminase, APOBEC1
- APOBEC1 Protein
- APOBEC-1 Protein
- APOBEC 1 Protein
- HEPR Protein
|
Below are MeSH descriptors whose meaning is more general than "APOBEC-1 Deaminase".
Below are MeSH descriptors whose meaning is more specific than "APOBEC-1 Deaminase".
This graph shows the total number of publications written about "APOBEC-1 Deaminase" by people in this website by year, and whether "APOBEC-1 Deaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "APOBEC-1 Deaminase" by people in Profiles.
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Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver. RNA. 2019 01; 25(1):70-81.
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Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 03 16; 543(7645):378-384.
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Adeno-associated virus serotype 8 gene therapy leads to significant lowering of plasma cholesterol levels in humanized mouse models of homozygous and heterozygous familial hypercholesterolemia. Hum Gene Ther. 2013 Jan; 24(1):19-26.
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Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):E2766-73.
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Mutational processes molding the genomes of 21 breast cancers. Cell. 2012 May 25; 149(5):979-93.
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Trib1 is a lipid- and myocardial infarction-associated gene that regulates hepatic lipogenesis and VLDL production in mice. J Clin Invest. 2010 Dec; 120(12):4410-4.
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Apolipoprotein B: from editosome to proteasome. Recent Prog Horm Res. 2000; 55:93-125; discussion 126.
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Normal perinatal rise in serum cholesterol is inhibited by hepatic delivery of adenoviral vector expressing apolipoprotein B mRNA editing enzyme (Apobec1) in rabbits. J Surg Res. 1999 Jul; 85(1):148-57.
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Production of rabbit polyclonal antibody against apobec-1 by genetic immunization. J Lipid Res. 1997 Dec; 38(12):2627-32.
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Tissue-specific inhibition of apolipoprotein B mRNA editing in the liver by adenovirus-mediated transfer of a dominant negative mutant APOBEC-1 leads to increased low density lipoprotein in mice. J Biol Chem. 1997 Jan 17; 272(3):1456-60.