Institute for Clinical and Translational Research

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RACHEL E. RAU

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Oncology
AddressDepartment of Pediatrics - Hem/Onc
6701 Fannin St., D1510
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Annesley CE, Rabik C, Duffield AS, Rau RE, Magoon D, Li L, Huff V, Small D, Loeb DA, Brown P. Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice. Oncotarget. 2018; 82(9):35313-35326.
    2. Schraw JM, Yiu TT, Lupo PJ, Tsavachidis S, Rau R, Bondy ML, Rabin KR, Shen L, Scheurer ME. Maternal folate genes and aberrant DNA hypermethylation in pediatric acute lymphoblastic leukemia. PLoS One. 2018; 13(5):e0197408. PMID: 29763473.
      View in: PubMed
    3. Schafer ES, Rau RE, Berg S, Liu X, Minard CG, D'Adamo D, Scott R, Reyderman L, Martinez G, Devarajan S, Reid JM, Fox E, Weigel BJ, Blaney SM. A phase 1 study of eribulin mesylate (E7389), a novel microtubule-targeting chemotherapeutic agent, in children with refractory or recurrent solid tumors: A Children's Oncology Group Phase 1 Consortium study (ADVL1314). Pediatr Blood Cancer. 2018 May 02; e27066. PMID: 29719113.
      View in: PubMed
    4. Rau RE, Dreyer Z, Choi MR, Liang W, Skowronski R, Allamneni KP, Devidas M, Raetz EA, Adamson PC, Blaney SM, Loh ML, Hunger SP. Outcome of pediatric patients with acute lymphoblastic leukemia/lymphoblastic lymphoma with hypersensitivity to pegaspargase treated with PEGylated Erwinia asparaginase, pegcrisantaspase: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2018 Mar; 65(3). PMID: 29090524.
      View in: PubMed
    5. Rau RE. CMML/JMML PDXs: as easy as 1, 2, NSG-SGM3. Blood. 2017 Jul 27; 130(4):385-386. PMID: 28751353.
      View in: PubMed
    6. Heikamp E, Rau R. 50 Years Ago in The Journal of Pediatrics: Sequential Therapy of Acute Leukemia in Childhood. J Pediatr. 2017 Apr; 183:140. PMID: 28343531.
      View in: PubMed
    7. Gramatges MM, Deshpande A, Lupo PJ, Rau RE, Redell ML, Horton TM, Scheurer ME, Rabin KR. Ethnic disparities relative to disease features and outcomes in children with acute myeloid leukemia. Pediatr Blood Cancer. 2017 Mar 07. PMID: 28266784.
      View in: PubMed
    8. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Göttgens B, Lee JS, Rau R, Li W, Goodell MA. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 Aug 08; 30(2):363-365. PMID: 27505680.
      View in: PubMed
    9. Rau RE, Carroll AJ, Heerema NA, Arland L, Carroll WL, Winick NJ, Raetz EA, Loh ML, Yang W, Relling MV, Dai Y, Devidas M, Hunger SP. Klinefelter syndrome and 47,XYY syndrome in children with B cell acute lymphoblastic leukaemia. Br J Haematol. 2016 Jul 19. PMID: 27434379.
      View in: PubMed
    10. Rau RE, Rodriguez B, Luo M, Jeong M, Rosen A, Rogers JH, Campbell CT, Daigle SR, Deng L, Song Y, Sweet S, Chevassut T, Andreeff M, Kornblau SM, Li W, Goodell MA. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 Jun 22. PMID: 27335278.
      View in: PubMed
    11. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Göttgens B, Lee JS, Rau R, Li W, Goodell MA. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 Jun 13; 29(6):922-934. PMID: 27300438.
      View in: PubMed
    12. Rau RE. Beyond KIT in CBF-AML: chromatin and cohesin. Blood. 2016 May 19; 127(20):2370-1. PMID: 27207321.
      View in: PubMed
    13. Eckstein OS, Wang L, Punia JN, Kornblau SM, Andreeff M, Wheeler DA, Goodell MA, Rau RE. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 May 18. PMID: 27208809.
      View in: PubMed
    14. Schafer ES, Rau RE, Liu X, Minard, CG, D’Adamo D, Scott R, Reyderman L, Martinez G, Fox E, Weigel BJ, Blaney SB. A phase 1 study of eribulin mesylate (E7389), a novel microtubule targeting chemotherapeutic agent in children with refractory or recurrent solid tumors (excluding CNS), including lymphomas: a Children’s Oncology Group Phase 1 Consortium study (ADVL1314). American Society of Clinical Oncology Annual Meeting. Poster presentation. Abstract #2567. 2016.
    15. Rau R, Brackett J. Prevention of mercaptopurine-induced hypoglycemia using allopurinol to reduce methylated thiopurine metabolites. American Society of Pediatric Hematology-Oncology Annual Meeting Abstracts. 2016.
    16. Annesley CE, Duffield AS, Rau RE, McCarty G, Magoon D, Li L, Huff V, Small D, Loeb D, Brown P. A Wilms Tumor 1 (WT1) Mutation Causes Myelodysplastic Syndrome in a Knock-in Mouse Model, and a Mixed Myelodysplastic/Myeloproliferative Neoplam in Double Knock-in Mice with WT1 and FLT3/ITD Mutations. Blood. 2015; 23(126).
    17. Cohen G, Annesley CE, Rau RE, Kelley S, Magoon D, Brown P. Targeting BCL6-Mediated Resistance to BCR-ABL Targeted Tyrosine Kinase Inhibitors (TKIs) in Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) through the Addition of Histone Deacetylase (HDAC) Inhibitors. Blood. 2015; 23(126):1277.
    18. Sayeed H, Fisher K, Gramatges M, Somvanshi S, Rau RE, Merritt BY, Roy A, Marcogliese A, Punia JN, Horton TM, Bertuch AA, Redell ML, Rabin KR, López-Terrada D. A customized targeted next-generation sequencing mutation panel for clinical use in pediatric hematologic malignancies: a pilot study. Blood. 2015; 23(126).
    19. Deshpande A, Gramatges MM, Sasa GS, Lupo PJ, Rau RE, Redell MS, Horton TM, Scheurer ME, Rabin KR. Poorer relapse-free survival in hispanic children diagnosed with acute myeloid leukemia compared with non-hispanics: a Texas single institution experience. Blood. 2015; 23(126).
    20. Yang L, Rau R, Goodell MA. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65. PMID: 25693834.
      View in: PubMed
    21. Sison EA, Magoon D, Li L, Annesley CE, Rau RE, Small D, Brown P. Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition. Oncotarget. 2014 Oct 15; 5(19):8947-58. PMID: 25333254; PMCID: PMC4253409.
      View in: PubMed, PubMed Central
    22. Matheny CJ, Wei MC, Bassik MC, Donnelly AJ, Kampmann M, Iwasaki M, Piloto O, Solow-Cordero DE, Bouley DM, Rau R, Brown P, McManus MT, Weissman JS, Cleary ML. Next-generation NAMPT inhibitors identified by sequential high-throughput phenotypic chemical and functional genomic screens. Chem Biol. 2013 Nov 21; 20(11):1352-63. PMID: 24183972.
      View in: PubMed
    23. Rau R, Magoon D, Greenblatt S, Li L, Annesley C, Duffield AS, Huso D, McIntyre E, Clohessy JG, Reschke M, Pandolfi PP, Small D, Brown P. NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease. Exp Hematol. 2014 Feb; 42(2):101-13.e5. PMID: 24184354; PMCID: PMC3932758.
      View in: PubMed, PubMed Central
    24. Sison EA, Rau RE, McIntyre E, Li L, Small D, Brown P. MLL-rearranged acute lymphoblastic leukaemia stem cell interactions with bone marrow stroma promote survival and therapeutic resistance that can be overcome with CXCR4 antagonism. Br J Haematol. 2013 Mar; 160(6):785-97. PMID: 23294096; PMCID: PMC4005340.
      View in: PubMed, PubMed Central
    25. Karafin M, Romagnoli M, Fink DL, Howard T, Rau R, Milstone AM, Carroll KC. Fatal infection caused by Cupriavidus gilardii in a child with aplastic anemia. J Clin Microbiol. 2010 Mar; 48(3):1005-7. PMID: 20071544.
      View in: PubMed
    26. Rau R, Brown P. Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity. Hematol Oncol. 2009 Dec; 27(4):171-81. PMID: 19569254.
      View in: PubMed
    27. Rau R, Fitzhugh CD, Baird K, Cortez KJ, Li L, Fischer SH, Cowen EW, Balow JE, Walsh TJ, Cohen JI, Wayne AS. Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: utility of PCR for early recognition and therapy. Pediatr Infect Dis J. 2008 Mar; 27(3):265-8. PMID: 18277922.
      View in: PubMed
    28. Brown P, McIntyre E, Rau R, Meshinchi S, Lacayo N, Dahl G, Alonzo TA, Chang M, Arceci RJ, Small D. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood. 2007 Aug 1; 110(3):979-85. PMID: 17440048.
      View in: PubMed
    29. Cordero L, Rau R, Taylor D, Ayers LW. Enteric gram-negative bacilli bloodstream infections: 17 years' experience in a neonatal intensive care unit. Am J Infect Control. 2004 Jun; 32(4):189-95. PMID: 15175611.
      View in: PubMed
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