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Fong Wilson Lam

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Critical Care
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    Collapse awards and honors
    2016 - 2017Alkek Award for Pilot Projects on Experimental Therapeutics, Baylor College of Medicine
    2017 - 2018Travel Award for Outstanding Young Investigators, The Microcirculatory Society
    2014 - 2015Micahel E. DeBakey Veterans Affairs Seed Award, Michael E. DeBakey Veterans Affairs Medical Center
    2017 - 2022NIGMS K08, National Institutes of Health

    Collapse Overview 
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    My clinical and research interests lie in the interactions between neutrophils, platelets, and endothelial cells in the microcirculation. These interactions lead to both the inflammation and thrombosis that occur in patients with inflammatory diseases. I am interested in understanding the mechanisms by which inflammation and thrombosis influence each other in order to develop novel therapies to reduce the morbidity and mortality from pathologic inflammation (such as sepsis, acute lung injury, trauma, and extracorporeal devices)

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    K08GM123261     (LAM, FONG WILSON)Apr 1, 2017 - Mar 31, 2022
    NIH/NIGMS
    UTILIZING SOLUBLE VIMENTIN AND ITS COMPONENTS TO ATTENUATE INFLAMMATION
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N. Retraction Note: A homing system targets therapeutic T cells to brain cancer. Nature. 2019 03; 567(7746):132. PMID: 30787441.
      View in: PubMed
    2. Gorgis NM, Kennedy C, Lam F, Thompson K, Coss-Bu J, Akcan Arikan A, Nguyen T, Hosek K, Miloh T, Karpen SJ, Penny DJ, Goss J, Desai MS. Clinical Consequences of Cardiomyopathy in Children With Biliary Atresia Requiring Liver Transplantation. Hepatology. 2019 Mar; 69(3):1206-1218. PMID: 30076624.
      View in: PubMed
    3. Onyearugbulem C, Williams L, Zhu H, Gazzaneo MC, Melicoff E, Das S, Coss-Bu J, Lam F, Mallory G, Munoz FM. Risk factors for infection after pediatric lung transplantation. Transpl Infect Dis. 2018 Dec; 20(6):e13000. PMID: 30221817.
      View in: PubMed
    4. Goldman J, Desai MS, McClain KL, Tcharmtchi MH, Kennedy CE, Thompson K, Lam F, Bashir DA, Chinn IK, Goldberg BR, Allen CE, Nguyen TC. Hepatobiliary Dysfunction and Disseminated Intravascular Coagulation Increase Risk of Mortality in Pediatric Hemophagocytic Lymphohistiocytosis. Pediatr Crit Care Med. 2018 10; 19(10):e522-e530. PMID: 30113519.
      View in: PubMed
    5. Samaha H, Pignata A, Fousek K, Ren J, Lam FW, Stossi F, Dubrulle J, Salsman VS, Krishnan S, Hong SH, Baker ML, Shree A, Gad AZ, Shum T, Fukumura D, Byrd TT, Mukherjee M, Marrelli SP, Orange JS, Joseph SK, Sorensen PH, Taylor MD, Hegde M, Mamonkin M, Jain RK, El-Naggar S, Ahmed N. A homing system targets therapeutic T cells to brain cancer. Nature. 2018 09; 561(7723):331-337. PMID: 30185905.
      View in: PubMed
    6. Akcan Arikan A, Srivaths P, Himes RW, Tufan Pekkucuksen N, Lam F, Nguyen T, Miloh T, Braun M, Goss J, Desai MS. Hybrid Extracorporeal Therapies as a Bridge to Pediatric Liver Transplantation. Pediatr Crit Care Med. 2018 07; 19(7):e342-e349. PMID: 29652753.
      View in: PubMed
    7. Da Q, Derry PJ, Lam FW, Rumbaut RE. Fluorescent labeling of endogenous platelets for intravital microscopy: Effects on platelet function. Microcirculation. 2018 08; 25(6):e12457. PMID: 29701894.
      View in: PubMed
    8. Wulff J, Margolin J, Coleman NE, Demmler-Harrison G, Lam F, Shah MD. A Severe Case of Murine Typhus Presenting With Anemia and Severe Thrombocytopenia. J Pediatr Hematol Oncol. 2018 04; 40(3):e185-e190. PMID: 29200167.
      View in: PubMed
    9. Lam FW, Da Q, Guillory B, Cruz MA. Recombinant Human Vimentin Binds to P-Selectin and Blocks Neutrophil Capture and Rolling on Platelets and Endothelium. J Immunol. 2018 03 01; 200(5):1718-1726. PMID: 29335256.
      View in: PubMed
    10. Krennerich E, Sitler CG, Shah M, Lam F, Graf J. Retrospective Review of Pediatric Transport: Where Do Our Patients Go After Transport? Air Med J. 2017 Nov - Dec; 36(6):332-338. PMID: 29132597.
      View in: PubMed
    11. Rana A, Kueht M, Desai M, Lam F, Miloh T, Moffett J, Galvan NT, Cotton R, O'Mahony C, Goss J. No Child Left Behind: Liver Transplantation in Critically Ill Children. J Am Coll Surg. 2017 Apr; 224(4):671-677. PMID: 28167225.
      View in: PubMed
    12. Lam FW, Cruz MA, Parikh K, Rumbaut RE. Histones stimulate von Willebrand factor release in vitro and in vivo. Haematologica. 2016 07; 101(7):e277-9. PMID: 27013650.
      View in: PubMed
    13. Lam FW, Rumbaut RE. Platelets mediate acetaminophen hepatotoxicity. Blood. 2015 Oct 08; 126(15):1738-9. PMID: 26450954.
      View in: PubMed
    14. Lam FW, Vijayan KV, Rumbaut RE. Platelets and Their Interactions with Other Immune Cells. Compr Physiol. 2015 Jul 01; 5(3):1265-80. PMID: 26140718.
      View in: PubMed
    15. Lam FW, Phillips J, Landry P, Magadi S, Smith CW, Rumbaut RE, Burns AR. Platelet recruitment promotes keratocyte repopulation following corneal epithelial abrasion in the mouse. PLoS One. 2015; 10(3):e0118950. PMID: 25775402.
      View in: PubMed
    16. Lam FW, Rumbaut RE, Burns AR. The Neutrophil: New Outlook for Old Cells, Edited by Dmitry Gabrilovich. Mechanisms of neutrophil migration. 2013; 129-188.
    17. Lam FW, Cruz MA, Leung HC, Parikh KS, Smith CW, Rumbaut RE. Histone induced platelet aggregation is inhibited by normal albumin. Thromb Res. 2013 Jul; 132(1):69-76. PMID: 23673386.
      View in: PubMed
    18. Nguyen T, Kyle UG, Jaimon N, Tcharmtchi MH, Coss-Bu JA, Lam F, Teruya J, Loftis L. Coinfection with Staphylococcus aureus increases risk of severe coagulopathy in critically ill children with influenza A (H1N1) virus infection. Crit Care Med. 2012 Dec; 40(12):3246-50. PMID: 22971587.
      View in: PubMed
    19. Stark RJ, Naik-Mathuria BJ, Lam FW, Olutoye OO, Sutton VR, Shekerdemian LS. Extracorporeal membrane oxygenation support of a severe metabolic crisis in a child with methylmalonic acidemia. ASAIO J. 2012 Jul-Aug; 58(4):438-9. PMID: 22711065.
      View in: PubMed
    20. Lam FW, Burns AR, Smith CW, Rumbaut RE. Platelets enhance neutrophil transendothelial migration via P-selectin glycoprotein ligand-1. Am J Physiol Heart Circ Physiol. 2011 Feb; 300(2):H468-75. PMID: 21169400.
      View in: PubMed
    21. Desai MS, Shabier Z, Taylor M, Lam F, Thevananther S, Kosters A, Karpen SJ. Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis. Hepatology. 2010 Jun; 51(6):2097-107. PMID: 20512997.
      View in: PubMed
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