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DANIEL MEDINA

TitleProfessor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
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    R01CA011944     (MEDINA, DANIEL NONE)Sep 30, 1977 - Apr 30, 2005
    NIH/NCI
    BIOLOGY OF MOUSE MAMMARY PRENEOPLASIAS
    Role: Principal Investigator

    R01CA039017     (MEDINA, DANIEL NONE)Jan 1, 1985 - Dec 31, 1987
    NIH/NCI
    CELL LINEAGES IN NORMAL AND PRENEOPLASTIC MAMMARY GROWTH
    Role: Principal Investigator

    R01CA047112     (MEDINA, DANIEL NONE)Apr 1, 1988 - Nov 30, 1999
    NIH/NCI
    EARLY EVENTS IN MULTIPLE-STAGE MAMMARY TUMORIGENESIS
    Role: Principal Investigator

    R13CA055154     (MEDINA, DANIEL NONE)Aug 1, 1991 - Jul 31, 1992
    NIH/NCI
    GORDON RESEARCH CONFERENCE--MAMMARY GLAND BIOLOGY
    Role: Principal Investigator

    R01CA063137     (MEDINA, DANIEL NONE)May 1, 1994 - Apr 30, 1997
    NIH/NCI
    IMMORTALIZATION AND MAMMORY TUMORIGENESIS
    Role: Principal Investigator

    P01CA064255     (MEDINA, DANIEL NONE)Aug 1, 1995 - Apr 30, 2008
    NIH/NCI
    Mechanisms of the Hormonal Prevention of Breast Cancer
    Role: Principal Investigator

    U01CA084243     (ROSEN, JEFFREY)Sep 30, 1999 - Mar 31, 2010
    NIH/NCI
    Mouse Models of Human Breast Cancer
    Role: Co-Principal Investigator

    R01CA084320     (MEDINA, DANIEL NONE)Jan 1, 2000 - Dec 31, 2005
    NIH/NCI
    P53 AND MOUSE MAMMARY TUMORIGENESIS
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gomes AM, Carron EC, Mills KL, Dow AM, Gray Z, Fecca CR, Lakey MA, Carmeliet P, Kittrell F, Medina D, Machado HL. Stromal Gas6 promotes the progression of premalignant mammary cells. Oncogene. 2019 04; 38(14):2437-2450. PMID: 30531835.
      View in: PubMed
    2. Smith GH, Medina D. Does the Mouse Mammary Gland Arise from Unipotent or Multipotent Mammary Stem/Progenitor Cells? J Mammary Gland Biol Neoplasia. 2018 06; 23(1-2):1-3. PMID: 29644495.
      View in: PubMed
    3. Palaniappan M, Edwards D, Creighton CJ, Medina D, Conneely OM. Reprogramming of the estrogen responsive transcriptome contributes to tamoxifen-dependent protection against tumorigenesis in the p53 null mammary epithelial cells. PLoS One. 2018; 13(3):e0194913. PMID: 29590203.
      View in: PubMed
    4. Dolfi SC, Medina DJ, Kareddula A, Paratala B, Rose A, Dhami J, Chen S, Ganesan S, Mackay G, Vazquez A, Hirshfield KM. Riluzole exerts distinct antitumor effects from a metabotropic glutamate receptor 1-specific inhibitor on breast cancer cells. Oncotarget. 2017 Jul 04; 8(27):44639-44653. PMID: 28591718.
      View in: PubMed
    5. Hansford H, Hong Y, Kittrell F, Medina D, Behbod F. Whole Mammary Gland Transplantation in Mice Protocol. Bio Protoc. 2017 Jun 05; 7(11). PMID: 29119128.
      View in: PubMed
    6. Carron EC, Homra S, Rosenberg J, Coffelt SB, Kittrell F, Zhang Y, Creighton CJ, Fuqua SA, Medina D, Machado HL. Macrophages promote the progression of premalignant mammary lesions to invasive cancer. Oncotarget. 2017 Aug 01; 8(31):50731-50746. PMID: 28881599.
      View in: PubMed
    7. Bansal N, Bartucci M, Yusuff S, Davis S, Flaherty K, Huselid E, Patrizii M, Jones D, Cao L, Sydorenko N, Moon YC, Zhong H, Medina DJ, Kerrigan J, Stein MN, Kim IY, Davis TW, DiPaola RS, Bertino JR, Sabaawy HE. BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer. Clin Cancer Res. 2016 Dec 15; 22(24):6176-6191. PMID: 27307599.
      View in: PubMed
    8. Kittrell F, Valdez K, Elsarraj H, Hong Y, Medina D, Behbod F. Mouse Mammary Intraductal (MIND) Method for Transplantation of Patient Derived Primary DCIS Cells and Cell Lines. Bio Protoc. 2016 Mar 05; 6(5). PMID: 27446983.
      View in: PubMed
    9. Di-Cicco A, Petit V, Chiche A, Bresson L, Romagnoli M, Orian-Rousseau V, Vivanco Md, Medina D, Faraldo MM, Glukhova MA, Deugnier MA. Paracrine Met signaling triggers epithelial-mesenchymal transition in mammary luminal progenitors, affecting their fate. Elife. 2015 Jul 13; 4. PMID: 26165517.
      View in: PubMed
    10. Zheng ZY, Tian L, Bu W, Fan C, Gao X, Wang H, Liao YH, Li Y, Lewis MT, Edwards D, Zwaka TP, Hilsenbeck SG, Medina D, Perou CM, Creighton CJ, Zhang XH, Chang EC. Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation. Cell Rep. 2015 Jul 21; 12(3):511-24. PMID: 26166574.
      View in: PubMed
    11. Suo J, Medina D, Herrera S, Zheng ZY, Jin L, Chamness GC, Contreras A, Gutierrez C, Hilsenbeck S, Umar A, Foekens JA, Hanash S, Schiff R, Zhang XH, Chang EC. Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells. Cell Biosci. 2015; 5:10. PMID: 25774287.
      View in: PubMed
    12. Dolfi SC, Jäger AV, Medina DJ, Haffty BG, Yang JM, Hirshfield KM. Fulvestrant treatment alters MDM2 protein turnover and sensitivity of human breast carcinoma cells to chemotherapeutic drugs. Cancer Lett. 2014 Aug 01; 350(1-2):52-60. PMID: 24747123.
      View in: PubMed
    13. Rebollar EA, Hughey MC, Harris RN, Domangue RJ, Medina D, Ibáñez R, Belden LK. The lethal fungus Batrachochytrium dendrobatidis is present in lowland tropical forests of far eastern Panamá. PLoS One. 2014; 9(4):e95484. PMID: 24740162.
      View in: PubMed
    14. Medina DJ, Abass-Shereef J, Walton K, Goodell L, Aviv H, Strair RK, Budak-Alpdogan T. Cobblestone-area forming cells derived from patients with mantle cell lymphoma are enriched for CD133+ tumor-initiating cells. PLoS One. 2014; 9(4):e91042. PMID: 24722054.
      View in: PubMed
    15. Mukherjee M, Ge G, Zhang N, Edwards DG, Sumazin P, Sharan SK, Rao PH, Medina D, Pati D. MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERa)-positive mammary adenocarcinomas. Oncogene. 2014 Nov 27; 33(48):5511-5522. PMID: 24276237.
      View in: PubMed
    16. Rehman SK, Li SH, Wyszomierski SL, Wang Q, Li P, Sahin O, Xiao Y, Zhang S, Xiong Y, Yang J, Wang H, Guo H, Zhang JD, Medina D, Muller WJ, Yu D. 14-3-3? orchestrates mammary tumor onset and progression via miR-221-mediated cell proliferation. Cancer Res. 2014 Jan 01; 74(1):363-373. PMID: 24197133.
      View in: PubMed
    17. Chiche A, Moumen M, Petit V, Jonkers J, Medina D, Deugnier MA, Faraldo MM, Glukhova MA. Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal. Stem Cells. 2013 Sep; 31(9):1857-67. PMID: 23712598.
      View in: PubMed
    18. Mehta MS, Dolfi SC, Bronfenbrener R, Bilal E, Chen C, Moore D, Lin Y, Rahim H, Aisner S, Kersellius RD, Teh J, Chen S, Toppmeyer DL, Medina DJ, Ganesan S, Vazquez A, Hirshfield KM. Metabotropic glutamate receptor 1 expression and its polymorphic variants associate with breast cancer phenotypes. PLoS One. 2013; 8(7):e69851. PMID: 23922822.
      View in: PubMed
    19. Medina D. Pregnancy protection of breast cancer: new insights reveal unanswered questions. Breast Cancer Res. 2013 May 08; 15(3):103. PMID: 23659596.
      View in: PubMed
    20. Machado HL, Kittrell FS, Edwards D, White AN, Atkinson RL, Rosen JM, Medina D, Lewis MT. Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cells Transl Med. 2013 Mar; 2(3):199-203. PMID: 23408103.
      View in: PubMed
    21. Raafat A, Strizzi L, Lashin K, Ginsburg E, McCurdy D, Salomon D, Smith GH, Medina D, Callahan R. Effects of age and parity on mammary gland lesions and progenitor cells in the FVB/N-RC mice. PLoS One. 2012; 7(8):e43624. PMID: 22952723.
      View in: PubMed
    22. Mazumdar A, Medina D, Kittrell FS, Zhang Y, Hill JL, Edwards DE, Bissonnette RP, Brown PH. The combination of tamoxifen and the rexinoid LG100268 prevents ER-positive and ER-negative mammary tumors in p53-null mammary gland mice. Cancer Prev Res (Phila). 2012 Oct; 5(10):1195-202. PMID: 22926341.
      View in: PubMed
    23. Lee S, Stewart S, Nagtegaal I, Luo J, Wu Y, Colditz G, Medina D, Allred DC. Differentially expressed genes regulating the progression of ductal carcinoma in situ to invasive breast cancer. Cancer Res. 2012 Sep 01; 72(17):4574-86. PMID: 22751464.
      View in: PubMed
    24. Medina D, Edwards DG, Kittrell F, Lee S, Allred DC. Intra-mammary ductal transplantation: a tool to study premalignant progression. J Mammary Gland Biol Neoplasia. 2012 Jun; 17(2):131-3. PMID: 22688217.
      View in: PubMed
    25. Lewis MT, Landua JD, Adams HC, Medina D. A mystery wrapped in an enigma: Matrigel enhancement of mammary cell growth and morphogenesis. J Mammary Gland Biol Neoplasia. 2012 Jun; 17(2):99-101. PMID: 22581302.
      View in: PubMed
    26. Valdez KE, Fan F, Smith W, Allred DC, Medina D, Behbod F. Human primary ductal carcinoma in situ (DCIS) subtype-specific pathology is preserved in a mouse intraductal (MIND) xenograft model. J Pathol. 2011 Dec; 225(4):565-73. PMID: 22025213.
      View in: PubMed
    27. Zhu M, Yi M, Kim CH, Deng C, Li Y, Medina D, Stephens RM, Green JE. Integrated miRNA and mRNA expression profiling of mouse mammary tumor models identifies miRNA signatures associated with mammary tumor lineage. Genome Biol. 2011 Aug 16; 12(8):R77. PMID: 21846369.
      View in: PubMed
    28. Herschkowitz JI, Zhao W, Zhang M, Usary J, Murrow G, Edwards D, Knezevic J, Greene SB, Darr D, Troester MA, Hilsenbeck SG, Medina D, Perou CM, Rosen JM. Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2778-83. PMID: 21633010.
      View in: PubMed
    29. Nguyen DH, Oketch-Rabah HA, Illa-Bochaca I, Geyer FC, Reis-Filho JS, Mao JH, Ravani SA, Zavadil J, Borowsky AD, Jerry DJ, Dunphy KA, Seo JH, Haslam S, Medina D, Barcellos-Hoff MH. Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type. Cancer Cell. 2011 May 17; 19(5):640-51. PMID: 21575864.
      View in: PubMed
    30. Kittrell FS, Carletti MZ, Kerbawy S, Heestand J, Xian W, Zhang M, Lamarca HL, Sonnenberg A, Rosen JM, Medina D, Behbod F. Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res. 2011 Apr 05; 13(2):R41. PMID: 21466693.
      View in: PubMed
    31. Bussard KM, Boulanger CA, Kittrell FS, Behbod F, Medina D, Smith GH. Immortalized, pre-malignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA. Breast Cancer Res. 2010; 12(5):R86. PMID: 20964820.
      View in: PubMed
    32. Medina D. Of mice and women: A short history of mouse mammary cancer research with an emphasis on the paradigms inspired by the transplantation method. Cold Spring Harb Perspect Biol. 2010 Oct; 2(10):a004523. PMID: 20630995.
      View in: PubMed
    33. Wang T, Gavin HM, Arlt VM, Lawrence BP, Fenton SE, Medina D, Vorderstrasse BA. Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors. Int J Cancer. 2011 Apr 01; 128(7):1509-23. PMID: 20521247.
      View in: PubMed
    34. Dearth RK, Delgado DA, Hiney JK, Pathiraja T, Oesterreich S, Medina D, Dees WL, Lee AV. Parity-induced decrease in systemic growth hormone alters mammary gland signaling: a potential role in pregnancy protection from breast cancer. Cancer Prev Res (Phila). 2010 Mar; 3(3):312-21. PMID: 20145191.
      View in: PubMed
    35. Yan H, Blackburn AC, McLary SC, Tao L, Roberts AL, Xavier EA, Dickinson ES, Seo JH, Arenas RB, Otis CN, Cao QJ, Lawlor RG, Osborne BA, Kittrell FS, Medina D, Jerry DJ. Pathways contributing to development of spontaneous mammary tumors in BALB/c-Trp53+/- mice. Am J Pathol. 2010 Mar; 176(3):1421-32. PMID: 20110418.
      View in: PubMed
    36. Kaipparettu BA, Dobrzycka KM, Britton O, Lee AV, Herron AJ, Li Y, Lewis MT, Medina D, Oesterreich S. Scaffold Attachment Factor B1 (SAFB1) heterozygosity does not influence Wnt-1 or DMBA-induced tumorigenesis. Mol Cancer. 2009 Mar 06; 8:15. PMID: 19267898.
      View in: PubMed
    37. Abba MC, Hu Y, Levy CC, Gaddis S, Kittrell FS, Hill J, Bissonnette RP, Brown PH, Medina D, Aldaz CM. Identification of modulated genes by three classes of chemopreventive agents at preneoplastic stages in a p53-null mouse mammary tumor model. Cancer Prev Res (Phila). 2009 Feb; 2(2):175-84. PMID: 19174580.
      View in: PubMed
    38. Medina D, Kittrell F, Hill J, Zhang Y, Hilsenbeck SG, Bissonette R, Brown PH. Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. Cancer Prev Res (Phila). 2009 Feb; 2(2):168-74. PMID: 19174577.
      View in: PubMed
    39. Behbod F, Kittrell FS, LaMarca H, Edwards D, Kerbawy S, Heestand JC, Young E, Mukhopadhyay P, Yeh HW, Allred DC, Hu M, Polyak K, Rosen JM, Medina D. An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res. 2009; 11(5):R66. PMID: 19735549.
      View in: PubMed
    40. Abba MC, Hu Y, Levy CC, Gaddis S, Kittrell FS, Zhang Y, Hill J, Bissonnette RP, Medina D, Brown PH, Aldaz CM. Transcriptomic signature of bexarotene (rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models. BMC Med Genomics. 2008 Sep 11; 1:40. PMID: 18786257.
      View in: PubMed
    41. Zhang N, Ge G, Meyer R, Sethi S, Basu D, Pradhan S, Zhao YJ, Li XN, Cai WW, El-Naggar AK, Baladandayuthapani V, Kittrell FS, Rao PH, Medina D, Pati D. Overexpression of Separase induces aneuploidy and mammary tumorigenesis. Proc Natl Acad Sci U S A. 2008 Sep 02; 105(35):13033-8. PMID: 18728194.
      View in: PubMed
    42. Allred DC, Medina D. The relevance of mouse models to understanding the development and progression of human breast cancer. J Mammary Gland Biol Neoplasia. 2008 Sep; 13(3):279-88. PMID: 18704660.
      View in: PubMed
    43. Medina D. Premalignant and malignant mammary lesions induced by MMTV and chemical carcinogens. J Mammary Gland Biol Neoplasia. 2008 Sep; 13(3):271-7. PMID: 18663563.
      View in: PubMed
    44. Zhang M, Behbod F, Atkinson RL, Landis MD, Kittrell F, Edwards D, Medina D, Tsimelzon A, Hilsenbeck S, Green JE, Michalowska AM, Rosen JM. Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res. 2008 Jun 15; 68(12):4674-82. PMID: 18559513.
      View in: PubMed
    45. Taddei I, Deugnier MA, Faraldo MM, Petit V, Bouvard D, Medina D, Fässler R, Thiery JP, Glukhova MA. Beta1 integrin deletion from the basal compartment of the mammary epithelium affects stem cells. Nat Cell Biol. 2008 Jun; 10(6):716-22. PMID: 18469806.
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    46. Smith GH, Medina D. Re-evaluation of mammary stem cell biology based on in vivo transplantation. Breast Cancer Res. 2008; 10(1):203. PMID: 18304381.
      View in: PubMed
    47. Parsa S, Ramasamy SK, De Langhe S, Gupte VV, Haigh JJ, Medina D, Bellusci S. Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling. Dev Biol. 2008 May 01; 317(1):121-31. PMID: 18381212.
      View in: PubMed
    48. Allred DC, Wu Y, Mao S, Nagtegaal ID, Lee S, Perou CM, Mohsin SK, O'Connell P, Tsimelzon A, Medina D. Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution. Clin Cancer Res. 2008 Jan 15; 14(2):370-8. PMID: 18223211.
      View in: PubMed
    49. Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Res. 2007 Dec 15; 67(24):12026-33. PMID: 18089834.
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    50. Li Z, Schem C, Shi YH, Medina D, Zhang M. Increased COX2 expression enhances tumor-induced osteoclastic lesions in breast cancer bone metastasis. Clin Exp Metastasis. 2008; 25(4):389-400. PMID: 17965942.
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    51. Gatza CE, Dumble M, Kittrell F, Edwards DG, Dearth RK, Lee AV, Xu J, Medina D, Donehower LA. Altered mammary gland development in the p53+/m mouse, a model of accelerated aging. Dev Biol. 2008 Jan 01; 313(1):130-41. PMID: 17996864.
      View in: PubMed
    52. Deeb KK, Michalowska AM, Yoon CY, Krummey SM, Hoenerhoff MJ, Kavanaugh C, Li MC, Demayo FJ, Linnoila I, Deng CX, Lee EY, Medina D, Shih JH, Green JE. Identification of an integrated SV40 T/t-antigen cancer signature in aggressive human breast, prostate, and lung carcinomas with poor prognosis. Cancer Res. 2007 Sep 01; 67(17):8065-80. PMID: 17804718.
      View in: PubMed
    53. Lee S, Medina D, Tsimelzon A, Mohsin SK, Mao S, Wu Y, Allred DC. Alterations of gene expression in the development of early hyperplastic precursors of breast cancer. Am J Pathol. 2007 Jul; 171(1):252-62. PMID: 17591970.
      View in: PubMed
    54. Koch JG, Gu X, Han Y, El-Naggar AK, Olson MV, Medina D, Jerry DJ, Blackburn AC, Peltz G, Amos CI, Lozano G. Mammary tumor modifiers in BALB/cJ mice heterozygous for p53. Mamm Genome. 2007 May; 18(5):300-9. PMID: 17557176.
      View in: PubMed
    55. Abba MC, Fabris VT, Hu Y, Kittrell FS, Cai WW, Donehower LA, Sahin A, Medina D, Aldaz CM. Identification of novel amplification gene targets in mouse and human breast cancer at a syntenic cluster mapping to mouse ch8A1 and human ch13q34. Cancer Res. 2007 May 01; 67(9):4104-12. PMID: 17483321.
      View in: PubMed
    56. Goepfert TM, Moreno-Smith M, Edwards DG, Pathak S, Medina D, Brinkley WR. Loss of chromosomal integrity drives rat mammary tumorigenesis. Int J Cancer. 2007 Mar 01; 120(5):985-94. PMID: 17131329.
      View in: PubMed
    57. Rajkumar L, Kittrell FS, Guzman RC, Brown PH, Nandi S, Medina D. Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models. Breast Cancer Res. 2007; 9(1):R12. PMID: 17257424.
      View in: PubMed
    58. Medina D. Chemical carcinogenesis of rat and mouse mammary glands. Breast Dis. 2007; 28:63-8. PMID: 18057544.
      View in: PubMed
    59. Deugnier MA, Faraldo MM, Teulière J, Thiery JP, Medina D, Glukhova MA. Isolation of mouse mammary epithelial progenitor cells with basal characteristics from the Comma-Dbeta cell line. Dev Biol. 2006 May 15; 293(2):414-25. PMID: 16545360.
      View in: PubMed
    60. Lee S, Mohsin SK, Mao S, Hilsenbeck SG, Medina D, Allred DC. Hormones, receptors, and growth in hyperplastic enlarged lobular units: early potential precursors of breast cancer. Breast Cancer Res. 2006; 8(1):R6. PMID: 16417654.
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    61. Medina D. Mammary developmental fate and breast cancer risk. Endocr Relat Cancer. 2005 Sep; 12(3):483-95. PMID: 16172188.
      View in: PubMed
    62. Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res. 2005 Sep 01; 65(17):7993-8002. PMID: 16140972.
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    63. Medina D, Kittrell FS, Hill J, Shepard A, Thordarson G, Brown P. Tamoxifen inhibition of estrogen receptor-alpha-negative mouse mammary tumorigenesis. Cancer Res. 2005 Apr 15; 65(8):3493-6. PMID: 15833886.
      View in: PubMed
    64. Blackman B, Russell T, Nordeen SK, Medina D, Neville MC. Claudin 7 expression and localization in the normal murine mammary gland and murine mammary tumors. Breast Cancer Res. 2005; 7(2):R248-55. PMID: 15743505.
      View in: PubMed
    65. Medina D, Kittrell F. Stroma is not a major target in DMBA-mediated tumorigenesis of mouse mammary preneoplasia. J Cell Sci. 2005 Jan 01; 118(Pt 1):123-7. PMID: 15585572.
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    66. Barcellos-Hoff MH, Medina D. New highlights on stroma-epithelial interactions in breast cancer. Breast Cancer Res. 2005; 7(1):33-6. PMID: 15642180.
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    67. Hu Y, Sun H, Drake J, Kittrell F, Abba MC, Deng L, Gaddis S, Sahin A, Baggerly K, Medina D, Aldaz CM. From mice to humans: identification of commonly deregulated genes in mammary cancer via comparative SAGE studies. Cancer Res. 2004 Nov 01; 64(21):7748-55. PMID: 15520179.
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    68. Allred DC, Brown P, Medina D. The origins of estrogen receptor alpha-positive and estrogen receptor alpha-negative human breast cancer. Breast Cancer Res. 2004; 6(6):240-5. PMID: 15535853.
      View in: PubMed
    69. Pati D, Haddad BR, Haegele A, Thompson H, Kittrell FS, Shepard A, Montagna C, Zhang N, Ge G, Otta SK, McCarthy M, Ullrich RL, Medina D. Hormone-induced chromosomal instability in p53-null mammary epithelium. Cancer Res. 2004 Aug 15; 64(16):5608-16. PMID: 15313898.
      View in: PubMed
    70. Yi Y, Shepard A, Kittrell F, Mulac-Jericevic B, Medina D, Said TK. p19ARF determines the balance between normal cell proliferation rate and apoptosis during mammary gland development. Mol Biol Cell. 2004 May; 15(5):2302-11. PMID: 15105443.
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    71. Medina D. Stromal fibroblasts influence human mammary epithelial cell morphogenesis. Proc Natl Acad Sci U S A. 2004 Apr 06; 101(14):4723-4. PMID: 15051868.
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    72. Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlén A, Olsson J, Otto HF, O'Malley B, Poustka A. Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer. 2004 Mar; 39(3):185-94. PMID: 14732920.
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    73. Medina D. Breast cancer: the protective effect of pregnancy. Clin Cancer Res. 2004 Jan 01; 10(1 Pt 2):380S-4S. PMID: 14734495.
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    74. Said TK, Medina D. Cell cycle genes in a mouse mammary hyperplasia model. J Mammary Gland Biol Neoplasia. 2004 Jan; 9(1):81-93. PMID: 15082920.
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    75. Medina D, Kittrell FS. p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis. Cancer Res. 2003 Oct 01; 63(19):6140-3. PMID: 14559792.
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    76. Medina D, Kittrell FS, Shepard A, Contreras A, Rosen JM, Lydon J. Hormone dependence in premalignant mammary progression. Cancer Res. 2003 Mar 01; 63(5):1067-72. PMID: 12615724.
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    77. Green JE, Cardiff R, Hennighausen L, Wakefield L, Wagner U, Lee E, Rosen J, Medina D, Nitkin A, Liu E. Validation of transgenic mammary cancer models: goals of the NCI Mouse Models of Human Cancer Consortium and the mammary cancer CD-ROM. Transgenic Res. 2002 Dec; 11(6):635-6. PMID: 12509138.
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    78. Kong G, Chua SS, Yijun Y, Kittrell F, Moraes RC, Medina D, Said TK. Functional analysis of cyclin D2 and p27(Kip1) in cyclin D2 transgenic mouse mammary gland during development. Oncogene. 2002 Oct 17; 21(47):7214-25. PMID: 12370811.
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    79. Medina D. Biological and molecular characteristics of the premalignant mouse mammary gland. Biochim Biophys Acta. 2002 Oct 02; 1603(1):1-9. PMID: 12242106.
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    80. Aldaz CM, Hu Y, Daniel R, Gaddis S, Kittrell F, Medina D. Serial analysis of gene expression in normal p53 null mammary epithelium. Oncogene. 2002 Sep 12; 21(41):6366-76. PMID: 12214277.
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    81. Goepfert TM, Adigun YE, Zhong L, Gay J, Medina D, Brinkley WR. Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. Cancer Res. 2002 Jul 15; 62(14):4115-22. PMID: 12124350.
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    82. Sivaraman L, Gay J, Hilsenbeck SG, Shine HD, Conneely OM, Medina D, O'Malley BW. Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat. 2002 May; 73(1):75-83. PMID: 12083633.
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    83. Medina D, Kittrell FS, Shepard A, Stephens LC, Jiang C, Lu J, Allred DC, McCarthy M, Ullrich RL. Biological and genetic properties of the p53 null preneoplastic mammary epithelium. FASEB J. 2002 Jun; 16(8):881-3. PMID: 11967232.
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    84. Cardiff RD, Bern HA, Faulkin LJ, Daniel CW, Smith GH, Young LJ, Medina D, Gardner MB, Wellings SR, Shyamala G, Guzman RC, Rajkumar L, Yang J, Thordarson G, Nandi S, MacLeod CL, Oshima RG, Man AK, Sawai ET, Gregg JP, Cheung AT, Lau DH. Contributions of mouse biology to breast cancer research. Comp Med. 2002 Feb; 52(1):12-31. PMID: 11900409.
      View in: PubMed
    85. Sivaraman L, Medina D. Hormone-induced protection against breast cancer. J Mammary Gland Biol Neoplasia. 2002 Jan; 7(1):77-92. PMID: 12160088.
      View in: PubMed
    86. Medina D, Ullrich R, Meyn R, Wiseman R, Donehower L. Environmental carcinogens and p53 tumor-suppressor gene interactions in a transgenic mouse model for mammary carcinogenesis. Environ Mol Mutagen. 2002; 39(2-3):178-83. PMID: 11921187.
      View in: PubMed
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