InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Virology & Microbiology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Infectious Diseases

    Collapse Research 
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    R01AI041050     (PIEDRA, PEDRO A)Sep 15, 1997 - Jan 31, 2009
    Control of Epidemic Influenza
    Role: Principal Investigator

    R43AI082834     (SHIRLEY, RENEE LYNN)Mar 15, 2010 - Feb 28, 2015
    Development of a plant-grown subunit vaccine against respiratory syncytial virus
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Farinholt T, Doddapaneni H, Qin X, Menon V, Meng Q, Metcalf G, Chao H, Gingras MC, Farinholt P, Agrawal C, Muzny DM, Piedra PA, Gibbs RA, Petrosino J. Transmission event of SARS-CoV-2 Delta variant reveals multiple vaccine breakthrough infections. medRxiv. 2021 Jul 12. PMID: 34268529.
    2. Hayden FG, Asher J, Cowling BJ, Hurt AC, Ikematsu H, Kuhlbusch K, Lemenuel-Diot A, Du Z, Meyers LA, Piedra PA, Takazono T, Yen HL, Monto AS. Reducing influenza virus transmission: the value of antiviral treatment. Clin Infect Dis. 2021 Jul 10. PMID: 34245250.
      Citations:    Fields:    
    3. Sahni LC, Avadhanula V, Ortiz CS, Feliz KE, John RE, Brown CA, Lively JY, Rha B, Munoz FM, Piedra PA, Dunn JJ, Boom JA. Comparison of Mid-Turbinate and Nasopharyngeal Specimens for Molecular Detection of SARS-CoV-2 Among Symptomatic Outpatients at a Pediatric Drive-Through Testing Site. J Pediatric Infect Dis Soc. 2021 Jun 26. PMID: 34173660.
      Citations:    Fields:    
    4. Raita Y, Pérez-Losada M, Freishtat RJ, Harmon B, Mansbach JM, Piedra PA, Zhu Z, Camargo CA, Hasegawa K. Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma. Nat Commun. 2021 06 14; 12(1):3601. PMID: 34127671.
      Citations:    Fields:    Translation:HumansCells
    5. Ivanov V, Oomens AGP, Papin JF, Staats R, Reuter DN, Yu Z, Piedra PA, Wellliver RC. Intranasal and intrapulmonary vaccination with an M protein-deficient respiratory syncytial virus (RSV) vaccine improves clinical signs and reduces viral replication in infant baboons after an RSV challenge infection. Vaccine. 2021 Jul 05; 39(30):4063-4071. PMID: 34140172.
      Citations:    Fields:    
    6. Nicholson EG, Avadhanula V, Fragoso S, Stroh R, Ye X, Bond N, Santarcangelo P, Stroh J, Piedra PA. SARS-CoV-2 re-infection versus prolonged shedding: A case series. Influenza Other Respir Viruses. 2021 Jun 04. PMID: 34085762.
      Citations: 1     Fields:    
    7. Salimi V, Viegas M, Trento A, Agoti CN, Anderson LJ, Avadhanula V, Bahl J, Bont L, Brister JR, Cane PA, Galiano M, Graham BS, Hatcher EL, Hellferscee O, Henke DM, Hirve S, Jackson S, Keyaerts E, Kragten-Tabatabaie L, Lindstrom S, Nauwelaers I, Nokes DJ, Openshaw PJ, Peret TC, Piedra PA, Ramaekers K, Rector A, Trovão NS, von Gottberg A, Zambon M, Zhang W, Williams TC, Barr IG, Buchholz UJ. Proposal for Human Respiratory Syncytial Virus Nomenclature below the Species Level. Emerg Infect Dis. 2021 06; 27(6):1-9. PMID: 34013862.
      Citations:    Fields:    Translation:HumansCells
    8. Ye X, Iwuchukwu OP, Avadhanula V, Aideyan LO, McBride TJ, Henke DM, Patel KD, Piedra FA, Angelo LS, Shah DP, Chemaly RF, Piedra PA. Humoral and Mucosal Antibody Response to RSV Structural Proteins in RSV-Infected Adult Hematopoietic Cell Transplant (HCT) Recipients. Viruses. 2021 May 26; 13(6). PMID: 34073490.
      Citations:    Fields:    
    9. Dawood FS, Varner M, Munoz F, Stockwell MS, Suyama J, Li DK, Tita A, Mathias L, Shakib JH, Piedra PA, Gyamfi-Bannerman C, Weissman A, Ferber J, Battarbee AN, Wesley MG, Vorwaller K, Powers E, Gibson M, Bond N, Santarcangelo P, Avadhanula V, Newes-Adeyi G, Hunt DR, Subramaniam A, Sanusi A, Boone A, Ogokeh C, Macio I, Odouli R, Thind P, Vargas CY, Almonte C, Galang R, Shapiro-Mendoza C, Campbell AP. Respiratory Viral Infections and Infection Prevention Practices among Women with Acute Respiratory Illness during Delivery Hospitalizations during the 2019-2020 Influenza Season. J Infect Dis. 2021 May 25. PMID: 34037764.
      Citations:    Fields:    
    10. Avadhanula V, Nicholson EG, Ferlic-Stark L, Piedra FA, Blunck BN, Fragoso S, Bond NL, Santarcangelo PL, Ye X, McBride TJ, Aideyan LO, Patel KD, Maurer L, Angelo LS, Piedra PA. Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 in Adults During the First and Second Wave of Coronavirus Disease 2019 Pandemic in Houston, Texas: The Potential of the Superspreader. J Infect Dis. 2021 05 20; 223(9):1528-1537. PMID: 33585934.
      Citations: 1     Fields:    Translation:Humans
    11. Blunck BN, Rezende W, Piedra PA. Profile of respiratory syncytial virus prefusogenic fusion protein nanoparticle vaccine. Expert Rev Vaccines. 2021 Apr; 20(4):351-364. PMID: 33733995.
      Citations:    Fields:    
    12. Symanski E, Ensor KB, Piedra PA, Sheth K, Caton K, Williams SL, Persse D, Banerjee D, Hopkins L. Population-Based Estimates of SARS-CoV-2 Seroprevalence in Houston, TX as of September 2020. J Infect Dis. 2021 Apr 29. PMID: 33914068.
      Citations:    Fields:    
    13. LaTurner ZW, Zong DM, Kalvapalle P, Gamas KR, Terwilliger A, Crosby T, Ali P, Avadhanula V, Santos HH, Weesner K, Hopkins L, Piedra PA, Maresso AW, Stadler LB. Evaluating recovery, cost, and throughput of different concentration methods for SARS-CoV-2 wastewater-based epidemiology. Water Res. 2021 Jun 01; 197:117043. PMID: 33784608.
      Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    14. Holmes EC, Hurt AC, Dobbie Z, Clinch B, Oxford JS, Piedra PA. Understanding the Impact of Resistance to Influenza Antivirals. Clin Microbiol Rev. 2021 03 17; 34(2). PMID: 33568554.
      Citations: 1     Fields:    
    15. Mansbach JM, Geller RJ, Hasegawa K, Piedra PA, Avadhanula V, Gern JE, Bochkov YA, Espinola JA, Sullivan AF, Camargo CA. Detection of Respiratory Syncytial Virus or Rhinovirus Weeks After Hospitalization for Bronchiolitis and the Risk of Recurrent Wheezing. J Infect Dis. 2021 Feb 03; 223(2):268-277. PMID: 32564083.
      Citations: 1     Fields:    
    16. Blunck BN, Aideyan L, Ye X, Avadhanula V, Ferlic-Stark L, Zechiedrich L, Gilbert BE, Piedra PA. A prospective surveillance study on the kinetics of the humoral immune response to the respiratory syncytial virus fusion protein in adults in Houston, Texas. Vaccine. 2021 02 22; 39(8):1248-1256. PMID: 33509697.
      Citations:    Fields:    Translation:HumansCells
    17. Tian JH, Patel N, Haupt R, Zhou H, Weston S, Hammond H, Logue J, Portnoff AD, Norton J, Guebre-Xabier M, Zhou B, Jacobson K, Maciejewski S, Khatoon R, Wisniewska M, Moffitt W, Kluepfel-Stahl S, Ekechukwu B, Papin J, Boddapati S, Jason Wong C, Piedra PA, Frieman MB, Massare MJ, Fries L, Bengtsson KL, Stertman L, Ellingsworth L, Glenn G, Smith G. SARS-CoV-2 spike glycoprotein vaccine candidate NVX-CoV2373 immunogenicity in baboons and protection in mice. Nat Commun. 2021 01 14; 12(1):372. PMID: 33446655.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    18. Doddapaneni H, Cregeen SJ, Sucgang R, Meng Q, Qin X, Avadhanula V, Chao H, Menon V, Nicholson E, Henke D, Piedra FA, Rajan A, Momin Z, Kottapalli K, Hoffman KL, Sedlazeck FJ, Metcalf G, Piedra PA, Muzny DM, Petrosino JF, Gibbs RA. Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 Individuals. bioRxiv. 2020 Dec 11. PMID: 33330863.
      Citations: 1     
    19. Guebre-Xabier M, Patel N, Tian JH, Zhou B, Maciejewski S, Lam K, Portnoff AD, Massare MJ, Frieman MB, Piedra PA, Ellingsworth L, Glenn G, Smith G. NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge. Vaccine. 2020 11 25; 38(50):7892-7896. PMID: 33139139.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    20. Cunningham S, Piedra PA, Martinon-Torres F, Szymanski H, Brackeva B, Dombrecht E, Detalle L, Fleurinck C. Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b trial. Lancet Respir Med. 2021 01; 9(1):21-32. PMID: 33002427.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    21. Ventura MJ, Guajardo E, Clark EH, Bhairavarasu K, Kherallah RY, DiNardo AR, Ye X, Piedra PA, Atmar RL, Agarwal SK. Correspondence on 'Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort' by Pouletty et al. Ann Rheum Dis. 2020 Sep 25. PMID: 32978236.
      Citations:    Fields:    
    22. Fujiogi M, Camargo CA, Raita Y, Toivonen L, Freishtat RJ, Mansbach JM, Piedra PA, Hasegawa K. Association of endemic coronaviruses with nasopharyngeal metabolome and microbiota among infants with severe bronchiolitis: a prospective multicenter study. Pediatr Res. 2021 May; 89(7):1594-1597. PMID: 32937650.
      Citations:    Fields:    
    23. Keech C, Albert G, Cho I, Robertson A, Reed P, Neal S, Plested JS, Zhu M, Cloney-Clark S, Zhou H, Smith G, Patel N, Frieman MB, Haupt RE, Logue J, McGrath M, Weston S, Piedra PA, Desai C, Callahan K, Lewis M, Price-Abbott P, Formica N, Shinde V, Fries L, Lickliter JD, Griffin P, Wilkinson B, Glenn GM. Phase 1-2 Trial of a SARS-CoV-2 Recombinant Spike Protein Nanoparticle Vaccine. N Engl J Med. 2020 12 10; 383(24):2320-2332. PMID: 32877576.
      Citations: 204     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    24. Nicholson EG, Piedra PA. Premature Infants With Respiratory Syncytial Virus (RSV): The Need for Both Maternal and Pediatric RSV Prevention Strategies. J Infect Dis. 2020 09 01; 222(7):1070-1072. PMID: 32006425.
      Citations:    Fields:    Translation:HumansCells
    25. Yokoyama T, Sakaguchi H, Ishibashi T, Shishido T, Piedra PA, Sato C, Tsuchiya K, Uehara T. Baloxavir Marboxil 2% Granules in Japanese Children With Influenza: An Open-label Phase 3 Study. Pediatr Infect Dis J. 2020 08; 39(8):706-712. PMID: 32433222.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    26. Baker J, Block SL, Matharu B, Burleigh Macutkiewicz L, Wildum S, Dimonaco S, Collinson N, Clinch B, Piedra PA. Baloxavir Marboxil Single-dose Treatment in Influenza-infected Children: A Randomized, Double-blind, Active Controlled Phase 3 Safety and Efficacy Trial (miniSTONE-2). Pediatr Infect Dis J. 2020 08; 39(8):700-705. PMID: 32516282.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    27. Madhi SA, Polack FP, Piedra PA, Munoz FM, Trenholme AA, Simões EAF, Swamy GK, Agrawal S, Ahmed K, August A, Baqui AH, Calvert A, Chen J, Cho I, Cotton MF, Cutland CL, Englund JA, Fix A, Gonik B, Hammitt L, Heath PT, de Jesus JN, Jones CE, Khalil A, Kimberlin DW, Libster R, Llapur CJ, Lucero M, Pérez Marc G, Marshall HS, Masenya MS, Martinón-Torres F, Meece JK, Nolan TM, Osman A, Perrett KP, Plested JS, Richmond PC, Snape MD, Shakib JH, Shinde V, Stoney T, Thomas DN, Tita AT, Varner MW, Vatish M, Vrbicky K, Wen J, Zaman K, Zar HJ, Glenn GM, Fries LF. Respiratory Syncytial Virus Vaccination during Pregnancy and Effects in Infants. N Engl J Med. 2020 07 30; 383(5):426-439. PMID: 32726529.
      Citations: 28     Fields:    Translation:HumansCellsPHPublic Health
    28. Doddapaneni H, Cregeen SJ, Sucgang R, Meng Q, Qin X, Avadhanula V, Chao H, Menon V, Nicholson E, Henke D, Piedra FA, Rajan A, Momin Z, Kottapalli K, Hoffman KL, Sedlazeck FJ, Metcalf G, Piedra PA, Muzny DM, Petrosino JF, Gibbs RA. Oligonucleotide capture sequencing of the SARS-CoV-2 genome and subgenomic fragments from COVID-19 individuals. bioRxiv. 2020 Jul 27. PMID: 32766579.
    29. Raita Y, Camargo CA, Macias CG, Mansbach JM, Piedra PA, Porter SC, Teach SJ, Hasegawa K. Machine learning-based prediction of acute severity in infants hospitalized for bronchiolitis: a multicenter prospective study. Sci Rep. 2020 07 03; 10(1):10979. PMID: 32620819.
      Citations: 1     Fields:    Translation:Humans
    30. Rha B, Curns AT, Lively JY, Campbell AP, Englund JA, Boom JA, Azimi PH, Weinberg GA, Staat MA, Selvarangan R, Halasa NB, McNeal MM, Klein EJ, Harrison CJ, Williams JV, Szilagyi PG, Singer MN, Sahni LC, Figueroa-Downing D, McDaniel D, Prill MM, Whitaker BL, Stewart LS, Schuster JE, Pahud BA, Weddle G, Avadhanula V, Munoz FM, Piedra PA, Payne DC, Langley G, Gerber SI. Respiratory Syncytial Virus-Associated Hospitalizations Among Young Children: 2015-2016. Pediatrics. 2020 07; 146(1). PMID: 32546583.
      Citations: 3     Fields:    Translation:Humans
    31. Mansbach JM, Hasegawa K, Piedra PA, Sullivan AF, Camargo CA. Severe Coronavirus Bronchiolitis in the Pre-COVID-19 Era. Pediatrics. 2020 09; 146(3). PMID: 32522783.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    32. Fujiogi M, Camargo CA, Raita Y, Bochkov YA, Gern JE, Mansbach JM, Piedra PA, Hasegawa K. Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study. Pediatr Allergy Immunol. 2020 10; 31(7):755-766. PMID: 32460384.
      Citations: 1     Fields:    Translation:HumansCells
    33. Fujiogi M, Camargo CA, Raita Y, Bochkov YA, Gern JE, Mansbach JM, Piedra PA, Hasegawa K. Association of rhinovirus species with nasopharyngeal metabolome in bronchiolitis infants: A multicenter study. Allergy. 2020 09; 75(9):2379-2383. PMID: 32306415.
      Citations: 3     Fields:    Translation:HumansCells
    34. Ye X, Cabral de Rezende W, Iwuchukwu OP, Avadhanula V, Ferlic-Stark LL, Patel KD, Piedra FA, Shah DP, Chemaly RF, Piedra PA. Antibody Response to the Furin Cleavable Twenty-Seven Amino Acid Peptide (p27) of the Fusion Protein in Respiratory Syncytial Virus (RSV) Infected Adult Hematopoietic Cell Transplant (HCT) Recipients. Vaccines (Basel). 2020 Apr 21; 8(2). PMID: 32326278.
      Citations: 2     
    35. Piedra PA. Long-Term Healthcare Costs Associated With Respiratory Syncytial Virus Infection in Children: The Domino Effect. J Infect Dis. 2020 03 28; 221(8):1205-1207. PMID: 30982897.
      Citations:    Fields:    Translation:HumansCells
    36. Fuentes S, Hahn M, Chilcote K, Chemaly RF, Shah DP, Ye X, Avadhanula V, Piedra PA, Golding H, Khurana S. Antigenic Fingerprinting of Respiratory Syncytial Virus (RSV)-A-Infected Hematopoietic Cell Transplant Recipients Reveals Importance of Mucosal Anti-RSV G Antibodies in Control of RSV Infection in Humans. J Infect Dis. 2020 02 03; 221(4):636-646. PMID: 31745552.
      Citations: 3     Fields:    Translation:HumansCells
    37. Piedra FA, Qiu X, Teng MN, Avadhanula V, Machado AA, Kim DK, Hixson J, Bahl J, Piedra PA. Non-gradient and genotype-dependent patterns of RSV gene expression. PLoS One. 2020; 15(1):e0227558. PMID: 31923213.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    38. Mansbach JM, Luna PN, Shaw CA, Hasegawa K, Petrosino JF, Piedra PA, Sullivan AF, Espinola JA, Stewart CJ, Camargo CA. Increased Moraxella and Streptococcus species abundance after severe bronchiolitis is associated with recurrent wheezing. J Allergy Clin Immunol. 2020 02; 145(2):518-527.e8. PMID: 31738994.
      Citations: 11     Fields:    Translation:HumansCells
    39. Munoz FM, Swamy GK, Hickman SP, Agrawal S, Piedra PA, Glenn GM, Patel N, August AM, Cho I, Fries L. Safety and Immunogenicity of a Respiratory Syncytial Virus Fusion (F) Protein Nanoparticle Vaccine in Healthy Third-Trimester Pregnant Women and Their Infants. J Infect Dis. 2019 10 22; 220(11):1802-1815. PMID: 31402384.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    40. Bergroth E, Aakula M, Elenius V, Remes S, Piippo-Savolainen E, Korppi M, Piedra PA, Bochkov YA, Gern JE, Camargo CA, Jartti T. Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma. J Allergy Clin Immunol Pract. 2020 02; 8(2):588-595.e4. PMID: 31520837.
      Citations: 7     Fields:    Translation:HumansCells
    41. Hasegawa K, Goto T, Hirayama A, Laham FR, Mansbach JM, Piedra PA, Camargo CA. Respiratory Virus Epidemiology Among US Infants With Severe Bronchiolitis: Analysis of 2 Multicenter, Multiyear Cohort Studies. Pediatr Infect Dis J. 2019 08; 38(8):e180-e183. PMID: 31306402.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    42. Stewart CJ, Mansbach JM, Piedra PA, Toivonen L, Camargo CA, Hasegawa K. Association of respiratory viruses with serum metabolome in infants with severe bronchiolitis. Pediatr Allergy Immunol. 2019 12; 30(8):848-851. PMID: 31231861.
      Citations: 5     Fields:    Translation:HumansCells
    43. Wang L, Piedra PA, Avadhanula V, Durigon EL, Machablishvili A, López MR, Thornburg NJ, Peret TCT. Duplex real-time RT-PCR assay for detection and subgroup-specific identification of human respiratory syncytial virus. J Virol Methods. 2019 09; 271:113676. PMID: 31181218.
      Citations:    Fields:    Translation:HumansCells
    44. Hasegawa K, Mansbach JM, Bochkov YA, Gern JE, Piedra PA, Bauer CS, Teach SJ, Wu S, Sullivan AF, Camargo CA. Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze. JAMA Pediatr. 2019 06 01; 173(6):544-552. PMID: 30933255.
      Citations: 9     Fields:    Translation:HumansCells
    45. Goetghebuer T, Smolen KK, Adler C, Das J, McBride T, Smits G, Lecomte S, Haelterman E, Barlow P, Piedra PA, Van der Klis F, Kollmann TR, Lauffenburger DA, Alter G, Levy J, Marchant A. Reply to Slogrove et al. Clin Infect Dis. 2019 05 30; 68(12):2158. PMID: 30535371.
      Citations:    Fields:    Translation:HumansCells
    46. Hause AM, Avadhanula V, Maccato ML, Pinell PM, Bond N, Santarcangelo P, Ferlic-Stark L, Ye X, Iwuchukwu O, Maurer L, Aideyan L, Dao K, McBride T, Piedra PA, Munoz FM. Clinical characteristics and outcomes of respiratory syncytial virus infection in pregnant women. Vaccine. 2019 06 06; 37(26):3464-3471. PMID: 31085002.
      Citations: 3     Fields:    Translation:HumansCells
    47. Mansbach JM, Hasegawa K, Piedra PA, Avadhanula V, Petrosino JF, Sullivan AF, Espinola JA, Camargo CA. Haemophilus-Dominant Nasopharyngeal Microbiota Is Associated With Delayed Clearance of Respiratory Syncytial Virus in Infants Hospitalized for Bronchiolitis. J Infect Dis. 2019 05 05; 219(11):1804-1808. PMID: 30590603.
      Citations: 5     Fields:    Translation:HumansCells
    48. Petrova EV, Avadhanula V, Michel S, Gincoo KE, Piedra PA, Anandasabapathy S. Remote Laboratory Management: Respiratory Virus Diagnostics. J Vis Exp. 2019 04 06; (146). PMID: 31009009.
      Citations: 1     Fields:    Translation:HumansCells
    49. Nicholson EG, Avadhanula V, Ferlic-Stark L, Patel K, Gincoo KE, Piedra PA. The Risk of Serious Bacterial Infection in Febrile Infants 0-90 Days of Life With a Respiratory Viral Infection. Pediatr Infect Dis J. 2019 04; 38(4):355-361. PMID: 30882724.
      Citations: 4     Fields:    Translation:HumansCells
    50. Ye X, Iwuchukwu OP, Avadhanula V, Aideyan LO, McBride TJ, Ferlic-Stark LL, Patel KD, Piedra FA, Shah DP, Chemaly RF, Piedra PA. Antigenic Site-Specific Competitive Antibody Responses to the Fusion Protein of Respiratory Syncytial Virus Were Associated With Viral Clearance in Hematopoietic Cell Transplantation Adults. Front Immunol. 2019; 10:706. PMID: 30984206.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    51. Goetghebuer T, Smolen KK, Adler C, Das J, McBride T, Smits G, Lecomte S, Haelterman E, Barlow P, Piedra PA, van der Klis F, Kollmann TR, Lauffenburger DA, Alter G, Levy J, Marchant A. Initiation of Antiretroviral Therapy Before Pregnancy Reduces the Risk of Infection-related Hospitalization in Human Immunodeficiency Virus-exposed Uninfected Infants Born in a High-income Country. Clin Infect Dis. 2019 03 19; 68(7):1193-1203. PMID: 30215689.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    52. Hasegawa K, Jartti T, Bochkov YA, Gern JE, Mansbach JM, Piedra PA, Toivonen L, Camargo CA. Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland. Pediatr Infect Dis J. 2019 03; 38(3):e59-e62. PMID: 30001231.
      Citations: 5     Fields:    Translation:HumansCells
    53. Hasegawa K, Hoptay CE, Harmon B, Celedón JC, Mansbach JM, Piedra PA, Freishtat RJ, Camargo CA. Association of type 2 cytokines in severe rhinovirus bronchiolitis during infancy with risk of developing asthma: A multicenter prospective study. Allergy. 2019 07; 74(7):1374-1377. PMID: 30656708.
      Citations: 5     Fields:    Translation:HumansCells
    54. Anderson LJ, Peret TC, Piedra PA. RSV Strains and Disease Severity. J Infect Dis. 2019 01 29; 219(4):514-516. PMID: 30215722.
      Citations: 5     Fields:    Translation:HumansCells
    55. Toivonen L, Camargo CA, Gern JE, Bochkov YA, Mansbach JM, Piedra PA, Hasegawa K. Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis. J Allergy Clin Immunol. 2019 05; 143(5):1925-1928.e7. PMID: 30654045.
      Citations: 8     Fields:    Translation:HumansCells
    56. Piedra PA. Live Attenuated Influenza Vaccine: Will the Phoenix Rise Again? Pediatrics. 2019 02; 143(2). PMID: 30617238.
      Citations:    Fields:    Translation:Humans
    57. Gilbert BE, Patel N, Lu H, Liu Y, Guebre-Xabier M, Piedra PA, Glenn G, Ellingsworth L, Smith G. Respiratory syncytial virus fusion nanoparticle vaccine immune responses target multiple neutralizing epitopes that contribute to protection against wild-type and palivizumab-resistant mutant virus challenge. Vaccine. 2018 12 18; 36(52):8069-8078. PMID: 30389195.
      Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    58. Dumas O, Hasegawa K, Mansbach JM, Sullivan AF, Piedra PA, Camargo CA. Severe bronchiolitis profiles and risk of recurrent wheeze by age 3 years. J Allergy Clin Immunol. 2019 04; 143(4):1371-1379.e7. PMID: 30240701.
      Citations: 13     Fields:    Translation:Humans
    59. Hause AM, Avadhanula V, Maccato ML, Pinell PM, Bond N, Santarcangelo P, Ferlic-Stark L, Munoz FM, Piedra PA. A Cross-sectional Surveillance Study of the Frequency and Etiology of Acute Respiratory Illness Among Pregnant Women. J Infect Dis. 2018 07 13; 218(4):528-535. PMID: 29741642.
      Citations: 5     Fields:    Translation:HumansCells
    60. Mazur NI, Higgins D, Nunes MC, Melero JA, Langedijk AC, Horsley N, Buchholz UJ, Openshaw PJ, McLellan JS, Englund JA, Mejias A, Karron RA, Simões EA, Knezevic I, Ramilo O, Piedra PA, Chu HY, Falsey AR, Nair H, Kragten-Tabatabaie L, Greenough A, Baraldi E, Papadopoulos NG, Vekemans J, Polack FP, Powell M, Satav A, Walsh EE, Stein RT, Graham BS, Bont LJ. The respiratory syncytial virus vaccine landscape: lessons from the graveyard and promising candidates. Lancet Infect Dis. 2018 10; 18(10):e295-e311. PMID: 29914800.
      Citations: 92     Fields:    Translation:Humans
    61. Hasegawa K, Piedra PA, Bauer CS, Celedón JC, Mansbach JM, Spergel JM, Espinola JA, Camargo CA. Nasopharyngeal CCL5 in infants with severe bronchiolitis and risk of recurrent wheezing: A multi-center prospective cohort study. Clin Exp Allergy. 2018 08; 48(8):1063-1067. PMID: 29756403.
      Citations: 6     Fields:    Translation:Humans
    62. Ye X, Iwuchukwu OP, Avadhanula V, Aideyan LO, McBride TJ, Ferlic-Stark LL, Patel KD, Piedra FA, Shah DP, Chemaly RF, Piedra PA. Comparison of Palivizumab-Like Antibody Binding to Different Conformations of the RSV F Protein in RSV-Infected Adult Hematopoietic Cell Transplant Recipients. J Infect Dis. 2018 03 28; 217(8):1247-1256. PMID: 29365155.
      Citations: 8     Fields:    Translation:HumansCells
    63. Stewart CJ, Hasegawa K, Wong MC, Ajami NJ, Petrosino JF, Piedra PA, Espinola JA, Tierney CN, Camargo CA, Mansbach JM. Respiratory Syncytial Virus and Rhinovirus Bronchiolitis Are Associated With Distinct Metabolic Pathways. J Infect Dis. 2018 03 13; 217(7):1160-1169. PMID: 29293990.
      Citations: 19     Fields:    Translation:HumansCells
    64. Hasegawa K, Pérez-Losada M, Hoptay CE, Epstein S, Mansbach JM, Teach SJ, Piedra PA, Camargo CA, Freishtat RJ. RSV vs. rhinovirus bronchiolitis: difference in nasal airway microRNA profiles and NF?B signaling. Pediatr Res. 2018 03; 83(3):606-614. PMID: 29244796.
      Citations: 13     Fields:    Translation:HumansCells
    65. Kulkarni PS, Hurwitz JL, Simões EAF, Piedra PA. Establishing Correlates of Protection for Vaccine Development: Considerations for the Respiratory Syncytial Virus Vaccine Field. Viral Immunol. 2018 03; 31(2):195-203. PMID: 29336703.
      Citations: 10     Fields:    Translation:HumansCells
    66. Luna PN, Hasegawa K, Ajami NJ, Espinola JA, Henke DM, Petrosino JF, Piedra PA, Sullivan AF, Camargo CA, Shaw CA, Mansbach JM. The association between anterior nares and nasopharyngeal microbiota in infants hospitalized for bronchiolitis. Microbiome. 2018 01 03; 6(1):2. PMID: 29298732.
      Citations: 11     Fields:    Translation:HumansCells
    67. Rodriguez-Fernandez R, Tapia LI, Yang CF, Torres JP, Chavez-Bueno S, Garcia C, Jaramillo LM, Moore-Clingenpeel M, Jafri HS, Peeples ME, Piedra PA, Ramilo O, Mejias A. Respiratory Syncytial Virus Genotypes, Host Immune Profiles, and Disease Severity in Young Children Hospitalized With Bronchiolitis. J Infect Dis. 2017 12 27; 217(1):24-34. PMID: 29045741.
      Citations: 21     Fields:    Translation:HumansCells
    68. Nicholson E, Piedra PA. Local Versus Global Enterovirus (EV) Surveillance: A Discussion for the Need for Active Surveillance to Guide EV-A71 Vaccines. J Infect Dis. 2017 12 12; 216(11):1337-1339. PMID: 29029227.
      Citations: 1     Fields:    Translation:HumansCells
    69. Hasegawa K, Linnemann RW, Mansbach JM, Ajami NJ, Espinola JA, Petrosino JF, Piedra PA, Stevenson MD, Sullivan AF, Thompson AD, Camargo CA. Nasal Airway Microbiota Profile and Severe Bronchiolitis in Infants: A Case-control Study. Pediatr Infect Dis J. 2017 Nov; 36(11):1044-1051. PMID: 28005692.
      Citations: 15     Fields:    Translation:HumansCells
    70. Kim L, Rha B, Abramson JS, Anderson LJ, Byington CL, Chen GL, DeVincenzo J, Edwards KM, Englund JA, Falsey AR, Griffin MR, Karron RA, Martin KG, Meissner HC, Munoz FM, Pavia AT, Piedra PA, Schaffner W, Simões EAF, Singleton R, Talbot HK, Walsh EE, Zucker JR, Gerber SI. Identifying Gaps in Respiratory Syncytial Virus Disease Epidemiology in the United States Prior to the Introduction of Vaccines. Clin Infect Dis. 2017 Sep 15; 65(6):1020-1025. PMID: 28903503.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    71. Tzannou I, Nicholas SK, Lulla P, Aguayo-Hiraldo PI, Misra A, Martinez CA, Machado AA, Orange JS, Piedra PA, Vera JF, Leen AM. Immunologic Profiling of Human Metapneumovirus for the Development of Targeted Immunotherapy. J Infect Dis. 2017 09 15; 216(6):678-687. PMID: 28934427.
      Citations: 12     Fields:    Translation:HumansCells
    72. Mansbach JM, Hasegawa K, Ajami NJ, Petrosino JF, Piedra PA, Tierney CN, Espinola JA, Camargo CA. Serum LL-37 Levels Associated With Severity of Bronchiolitis and Viral Etiology. Clin Infect Dis. 2017 Sep 15; 65(6):967-975. PMID: 28541502.
      Citations: 9     Fields:    Translation:HumansCells
    73. Laham FR, Mansbach JM, Piedra PA, Hasegawa K, Sullivan AF, Espinola JA, Camargo CA. Clinical Profiles of Respiratory Syncytial Virus Subtypes A AND B Among Children Hospitalized with Bronchiolitis. Pediatr Infect Dis J. 2017 08; 36(8):808-810. PMID: 28383391.
      Citations: 8     Fields:    Translation:HumansCells
    74. Davis J, Thompson AD, Mansbach JM, Piedra PA, Kasagawa K, Sullivan AF, Espinola JA, Camargo CA. Multicenter Observational Study of the Use of Nebulized Hypertonic Saline to Treat Children Hospitalized for Bronchiolitis From 2008 to 2014. Hosp Pediatr. 2017 Jul 31. PMID: 28761004.
      Citations:    Fields:    
    75. Aguayo-Hiraldo PI, Arasaratnam RJ, Tzannou I, Kuvalekar M, Lulla P, Naik S, Martinez CA, Piedra PA, Vera JF, Leen AM. Characterizing the Cellular Immune Response to Parainfluenza Virus 3. J Infect Dis. 2017 07 15; 216(2):153-161. PMID: 28472480.
      Citations: 11     Fields:    Translation:HumansCells
    76. Hause AM, Henke DM, Avadhanula V, Shaw CA, Tapia LI, Piedra PA. Correction: Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B. PLoS One. 2017; 12(6):e0180623. PMID: 28658276.
      Citations:    Fields:    
    77. Elenius V, Bergroth E, Koponen P, Remes S, Piedra PA, Espinola JA, Korppi M, Camargo CA, Jartti T. Marked variability observed in inpatient management of bronchiolitis in three Finnish hospitals. Acta Paediatr. 2017 Sep; 106(9):1512-1518. PMID: 28544041.
      Citations: 3     Fields:    Translation:Humans
    78. August A, Glenn GM, Kpamegan E, Hickman SP, Jani D, Lu H, Thomas DN, Wen J, Piedra PA, Fries LF. A Phase 2 randomized, observer-blind, placebo-controlled, dose-ranging trial of aluminum-adjuvanted respiratory syncytial virus F particle vaccine formulations in healthy women of childbearing age. Vaccine. 2017 06 27; 35(30):3749-3759. PMID: 28579233.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    79. Hause AM, Henke DM, Avadhanula V, Shaw CA, Tapia LI, Piedra PA. Sequence variability of the respiratory syncytial virus (RSV) fusion gene among contemporary and historical genotypes of RSV/A and RSV/B. PLoS One. 2017; 12(4):e0175792. PMID: 28414749.
      Citations: 17     Fields:    Translation:HumansCells
    80. Fries L, Shinde V, Stoddard JJ, Thomas DN, Kpamegan E, Lu H, Smith G, Hickman SP, Piedra P, Glenn GM. Immunogenicity and safety of a respiratory syncytial virus fusion protein (RSV F) nanoparticle vaccine in older adults. Immun Ageing. 2017; 14:8. PMID: 28413427.
      Citations: 25     
    81. Hasegawa K, Mansbach JM, Ajami NJ, Petrosino JF, Freishtat RJ, Teach SJ, Piedra PA, Camargo CA. The relationship between nasopharyngeal CCL5 and microbiota on disease severity among infants with bronchiolitis. Allergy. 2017 Nov; 72(11):1796-1800. PMID: 28306146.
      Citations: 10     Fields:    Translation:HumansCells
    82. Espinosa Y, San Martín C, Torres AA, Farfán MJ, Torres JP, Avadhanula V, Piedra PA, Tapia LI. Genomic Loads and Genotypes of Respiratory Syncytial Virus: Viral Factors during Lower Respiratory Tract Infection in Chilean Hospitalized Infants. Int J Mol Sci. 2017 Mar 21; 18(3). PMID: 28335547.
      Citations: 6     Fields:    Translation:HumansCells
    83. Piedra FA, Mei M, Avadhanula V, Mehta R, Aideyan L, Garofalo RP, Piedra PA. The interdependencies of viral load, the innate immune response, and clinical outcome in children presenting to the emergency department with respiratory syncytial virus-associated bronchiolitis. PLoS One. 2017; 12(3):e0172953. PMID: 28267794.
      Citations: 16     Fields:    Translation:HumansCells
    84. Stobart CC, Rostad CA, Ke Z, Dillard RS, Hampton CM, Strauss JD, Yi H, Hotard AL, Meng J, Pickles RJ, Sakamoto K, Lee S, Currier MG, Moin SM, Graham BS, Boukhvalova MS, Gilbert BE, Blanco JC, Piedra PA, Wright ER, Moore ML. A live RSV vaccine with engineered thermostability is immunogenic in cotton rats despite high attenuation. Nat Commun. 2016 12 21; 7:13916. PMID: 28000669.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    85. Hasegawa K, Mansbach JM, Ajami NJ, Petrosino JF, Freishtat RJ, Teach SJ, Piedra PA, Camargo CA. Serum cathelicidin, nasopharyngeal microbiota, and disease severity among infants hospitalized with bronchiolitis. J Allergy Clin Immunol. 2017 04; 139(4):1383-1386.e6. PMID: 27845236.
      Citations: 15     Fields:    Translation:Humans
    86. Hasegawa K, Mansbach JM, Ajami NJ, Espinola JA, Henke DM, Petrosino JF, Piedra PA, Shaw CA, Sullivan AF, Camargo CA. Association of nasopharyngeal microbiota profiles with bronchiolitis severity in infants hospitalised for bronchiolitis. Eur Respir J. 2016 11; 48(5):1329-1339. PMID: 27799386.
      Citations: 52     Fields:    Translation:HumansCells
    87. Mosquera RA, Gomez-Rubio AM, Harris T, Yadav A, McBeth K, Gonzales T, Jon C, Stark J, Avritscher E, Pedroza C, Smith K, Colasurdo G, Wootton S, Piedra P, Tyson JE, Samuels C. Anti-inflammatory effect of prophylactic macrolides on children with chronic lung disease: a protocol for a double-blinded randomised controlled trial. BMJ Open. 2016 09 16; 6(9):e012060. PMID: 27638496.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    88. Rostad CA, Stobart CC, Gilbert BE, Pickles RJ, Hotard AL, Meng J, Blanco JCG, Moin SM, Graham BS, Piedra PA, Moore ML. A Recombinant Respiratory Syncytial Virus Vaccine Candidate Attenuated by a Low-Fusion F Protein Is Immunogenic and Protective against Challenge in Cotton Rats. J Virol. 2016 08 15; 90(16):7508-7518. PMID: 27279612.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    89. Hasegawa K, Linnemann RW, Mansbach JM, Ajami NJ, Espinola JA, Petrosino JF, Piedra PA, Stevenson MD, Sullivan AF, Thompson AD, Camargo CA. The Fecal Microbiota Profile and Bronchiolitis in Infants. Pediatrics. 2016 07; 138(1). PMID: 27354456.
      Citations: 19     Fields:    Translation:Humans
    90. Dumas O, Mansbach JM, Jartti T, Hasegawa K, Sullivan AF, Piedra PA, Camargo CA. A clustering approach to identify severe bronchiolitis profiles in children. Thorax. 2016 08; 71(8):712-8. PMID: 27339060.
      Citations: 18     Fields:    Translation:Humans
    91. Nicholson EG, Schlegel C, Garofalo RP, Mehta R, Scheffler M, Mei M, Piedra PA. Robust Cytokine and Chemokine Response in Nasopharyngeal Secretions: Association With Decreased Severity in Children With Physician Diagnosed Bronchiolitis. J Infect Dis. 2016 08 15; 214(4):649-55. PMID: 27190183.
      Citations: 9     Fields:    Translation:HumansCells
    92. Flannery B, Zimmerman RK, Gubareva LV, Garten RJ, Chung JR, Nowalk MP, Jackson ML, Jackson LA, Monto AS, Ohmit SE, Belongia EA, McLean HQ, Gaglani M, Piedra PA, Mishin VP, Chesnokov AP, Spencer S, Thaker SN, Barnes JR, Foust A, Sessions W, Xu X, Katz J, Fry AM. Enhanced Genetic Characterization of Influenza A(H3N2) Viruses and Vaccine Effectiveness by Genetic Group, 2014-2015. J Infect Dis. 2016 10 01; 214(7):1010-9. PMID: 27190176.
      Citations: 50     Fields:    Translation:HumansCells
    93. Mansbach JM, Hasegawa K, Henke DM, Ajami NJ, Petrosino JF, Shaw CA, Piedra PA, Sullivan AF, Espinola JA, Camargo CA. Respiratory syncytial virus and rhinovirus severe bronchiolitis are associated with distinct nasopharyngeal microbiota. J Allergy Clin Immunol. 2016 06; 137(6):1909-1913.e4. PMID: 27061249.
      Citations: 38     Fields:    Translation:HumansCellsCTClinical Trials
    94. Bergroth E, Aakula M, Korppi M, Remes S, Kivistö JE, Piedra PA, Camargo CA, Jartti T. Post-bronchiolitis Use of Asthma Medication: A Prospective 1-year Follow-up Study. Pediatr Infect Dis J. 2016 Apr; 35(4):363-8. PMID: 26658529.
      Citations: 9     Fields:    Translation:Humans
    95. Mansbach JM, Clark S, Teach SJ, Gern JE, Piedra PA, Sullivan AF, Espinola JA, Camargo CA. Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics. J Pediatr. 2016 05; 172:202-204.e1. PMID: 26875009.
      Citations: 13     Fields:    Translation:HumansCells
    96. Korppi M, Kivistö J, Koponen P, Lehtinen P, Remes S, Piippo-Savolainen E, Piedra PA, Espinola JA, Camargo CA, Jartti T. Absence of Bordetella pertussis Among Infants Hospitalized for Bronchiolitis in Finland, 2008-2010. Pediatr Infect Dis J. 2016 Feb; 35(2):219-21. PMID: 26551447.
      Citations:    Fields:    Translation:HumansCells
    97. Gaglani M, Pruszynski J, Murthy K, Clipper L, Robertson A, Reis M, Chung JR, Piedra PA, Avadhanula V, Nowalk MP, Zimmerman RK, Jackson ML, Jackson LA, Petrie JG, Ohmit SE, Monto AS, McLean HQ, Belongia EA, Fry AM, Flannery B. Influenza Vaccine Effectiveness Against 2009 Pandemic Influenza A(H1N1) Virus Differed by Vaccine Type During 2013-2014 in the United States. J Infect Dis. 2016 May 15; 213(10):1546-56. PMID: 26743842.
      Citations: 66     Fields:    Translation:HumansCellsPHPublic Health
    98. Piedra PA, Hause AM, Aideyan L. Respiratory Syncytial Virus (RSV): Neutralizing Antibody, a Correlate of Immune Protection. Methods Mol Biol. 2016; 1442:77-91. PMID: 27464689.
      Citations: 6     Fields:    Translation:HumansCells
    99. Perron M, Stray K, Kinkade A, Theodore D, Lee G, Eisenberg E, Sangi M, Gilbert BE, Jordan R, Piedra PA, Toms GL, Mackman R, Cihlar T. GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process. Antimicrob Agents Chemother. 2015 Dec 14; 60(3):1264-73. PMID: 26666922.
      Citations: 20     Fields:    Translation:HumansCells
    100. Hasegawa K, Linnemann RW, Avadhanula V, Mansbach JM, Piedra PA, Gern JE, Camargo CA. Detection of respiratory syncytial virus and rhinovirus in healthy infants. BMC Res Notes. 2015 Nov 25; 8:718. PMID: 26608824.
      Citations: 11     Fields:    Translation:HumansCells
    101. Stevenson MD, Mansbach JM, Mowad E, Dunn M, Clark S, Piedra PA, Sullivan AF, Camargo CA. Prenatal Versus Postnatal Tobacco Smoke Exposure and Intensive Care Use in Children Hospitalized With Bronchiolitis. Acad Pediatr. 2016 07; 16(5):446-452. PMID: 26555856.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    102. Detalle L, Stohr T, Palomo C, Piedra PA, Gilbert BE, Mas V, Millar A, Power UF, Stortelers C, Allosery K, Melero JA, Depla E. Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection. Antimicrob Agents Chemother. 2016 01; 60(1):6-13. PMID: 26438495.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    103. Hasegawa K, Mansbach JM, Piedra PA, Dunn MB, Clark S, Sullivan AF, Camargo CA. Eligibility for palivizumab prophylaxis in a cohort of children with severe bronchiolitis. Pediatr Int. 2015 Oct; 57(5):1031-4. PMID: 26508190.
      Citations:    Fields:    Translation:Humans
    104. Simões EA, Carbonell-Estrany X, Guilbert T, Mansbach JM, Piedra PA, Ramilo O, Welliver R. Clinical Endpoints for Respiratory Syncytial Virus Prophylaxis Trials in Infants and Children in High-income and Middle-income Countries. Pediatr Infect Dis J. 2015 Oct; 34(10):1086-92. PMID: 26121204.
      Citations: 4     Fields:    Translation:Humans
    105. Spencer S, Chung J, Thompson M, Piedra PA, Jewell A, Avadhanula V, Mei M, Jackson ML, Meece J, Sundaram M, Belongia EA, Cross R, Johnson E, Bullotta A, Rinaldo C, Gaglani M, Murthy K, Clipper L, Berman L, Flannery B. Factors associated with real-time RT-PCR cycle threshold values among medically attended influenza episodes. J Med Virol. 2016 Apr; 88(4):719-23. PMID: 26334765.
      Citations: 7     Fields:    Translation:HumansCells
    106. Glenn GM, Fries LF, Thomas DN, Smith G, Kpamegan E, Lu H, Flyer D, Jani D, Hickman SP, Piedra PA. A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age. J Infect Dis. 2016 Feb 01; 213(3):411-22. PMID: 26259809.
      Citations: 49     Fields:    Translation:HumansCells
    107. Hasegawa K, Stevenson MD, Mansbach JM, Schroeder AR, Sullivan AF, Espinola JA, Piedra PA, Camargo CA. Association Between Hyponatremia and Higher Bronchiolitis Severity Among Children in the ICU With Bronchiolitis. Hosp Pediatr. 2015 Jul; 5(7):385-9. PMID: 26136313.
      Citations: 2     Fields:    Translation:Humans
    108. Piedra PA, Mansbach JM, Jewell AM, Thakar SD, Grant CC, Sullivan AF, Espinola JA, Camargo CA. Bordetella pertussis is an uncommon pathogen in children hospitalized with bronchiolitis during the winter season. Pediatr Infect Dis J. 2015 Jun; 34(6):566-70. PMID: 25970109.
      Citations: 5     Fields:    Translation:HumansCells
    109. Kim E, Okada K, Beeler JA, Crim RL, Steitz J, Piedra PA, Gilbert BE, Gambotto A. Correction for Kim et al., development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat model. J Virol. 2015 May; 89(9):5193. PMID: 25841050.
      Citations:    Fields:    
    110. O'Donnell K, Mansbach JM, LoVecchio F, Cheng J, Piedra PA, Clark S, Sullivan AF, Camargo CA. Use of Cough and Cold Medications in Severe Bronchiolitis before and after a Health Advisory Warning against Their Use. J Pediatr. 2015 Jul; 167(1):196-8.e1-2. PMID: 25888349.
      Citations:    Fields:    Translation:HumansPHPublic Health
    111. Pierce HC, Mansbach JM, Fisher ES, Macias CG, Pate BM, Piedra PA, Sullivan AF, Espinola JA, Camargo CA. Variability of intensive care management for children with bronchiolitis. Hosp Pediatr. 2015 Apr; 5(4):175-84. PMID: 25832972.
      Citations: 12     Fields:    Translation:Humans
    112. Jartti T, Hasegawa K, Mansbach JM, Piedra PA, Camargo CA. Rhinovirus-induced bronchiolitis: Lack of association between virus genomic load and short-term outcomes. J Allergy Clin Immunol. 2015 Aug; 136(2):509-12.e11. PMID: 25840721.
      Citations: 11     Fields:    Translation:HumansCells
    113. Mansbach JM, Clark S, Piedra PA, Macias CG, Schroeder AR, Pate BM, Sullivan AF, Espinola JA, Camargo CA. Hospital course and discharge criteria for children hospitalized with bronchiolitis. J Hosp Med. 2015 Apr; 10(4):205-11. PMID: 25627657.
      Citations: 7     Fields:    Translation:Humans
    114. Mackman RL, Sangi M, Sperandio D, Parrish JP, Eisenberg E, Perron M, Hui H, Zhang L, Siegel D, Yang H, Saunders O, Boojamra C, Lee G, Samuel D, Babaoglu K, Carey A, Gilbert BE, Piedra PA, Strickley R, Iwata Q, Hayes J, Stray K, Kinkade A, Theodore D, Jordan R, Desai M, Cihlar T. Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. J Med Chem. 2015 Feb 26; 58(4):1630-43. PMID: 25574686.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    115. Hasegawa K, Pate BM, Mansbach JM, Macias CG, Fisher ES, Piedra PA, Espinola JA, Sullivan AF, Camargo CA. Risk factors for requiring intensive care among children admitted to ward with bronchiolitis. Acad Pediatr. 2015 Jan-Feb; 15(1):77-81. PMID: 25528126.
      Citations: 16     Fields:    Translation:Humans
    116. Hasegawa K, Jartti T, Mansbach JM, Laham FR, Jewell AM, Espinola JA, Piedra PA, Camargo CA. Respiratory syncytial virus genomic load and disease severity among children hospitalized with bronchiolitis: multicenter cohort studies in the United States and Finland. J Infect Dis. 2015 May 15; 211(10):1550-9. PMID: 25425699.
      Citations: 54     Fields:    Translation:HumansCells
    117. McLean HQ, Thompson MG, Sundaram ME, Kieke BA, Gaglani M, Murthy K, Piedra PA, Zimmerman RK, Nowalk MP, Raviotta JM, Jackson ML, Jackson L, Ohmit SE, Petrie JG, Monto AS, Meece JK, Thaker SN, Clippard JR, Spencer SM, Fry AM, Belongia EA. Influenza vaccine effectiveness in the United States during 2012-2013: variable protection by age and virus type. J Infect Dis. 2015 May 15; 211(10):1529-40. PMID: 25406334.
      Citations: 105     Fields:    Translation:HumansCells
    118. Macias CG, Mansbach JM, Fisher ES, Riederer M, Piedra PA, Sullivan AF, Espinola JA, Camargo CA. Variability in inpatient management of children hospitalized with bronchiolitis. Acad Pediatr. 2015 Jan-Feb; 15(1):69-76. PMID: 25444654.
      Citations: 10     Fields:    Translation:Humans
    119. Schepens B, Sedeyn K, Vande Ginste L, De Baets S, Schotsaert M, Roose K, Houspie L, Van Ranst M, Gilbert B, van Rooijen N, Fiers W, Piedra P, Saelens X. Protection and mechanism of action of a novel human respiratory syncytial virus vaccine candidate based on the extracellular domain of small hydrophobic protein. EMBO Mol Med. 2014 Nov; 6(11):1436-54. PMID: 25298406.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    120. Avadhanula V, Chemaly RF, Shah DP, Ghantoji SS, Azzi JM, Aideyan LO, Mei M, Piedra PA. Infection with novel respiratory syncytial virus genotype Ontario (ON1) in adult hematopoietic cell transplant recipients, Texas, 2011-2013. J Infect Dis. 2015 Feb 15; 211(4):582-9. PMID: 25156562.
      Citations: 18     Fields:    Translation:HumansCells
    121. Mehta R, Scheffler M, Tapia L, Aideyan L, Patel KD, Jewell AM, Avadhanula V, Mei M, Garofalo RP, Piedra PA. Lactate dehydrogenase and caspase activity in nasopharyngeal secretions are predictors of bronchiolitis severity. Influenza Other Respir Viruses. 2014 Nov; 8(6):617-25. PMID: 25132512.
      Citations: 7     Fields:    Translation:Humans
    122. Jartti T, Aakula M, Mansbach JM, Piedra PA, Bergroth E, Koponen P, Kivistö JE, Sullivan AF, Espinola JA, Remes S, Korppi M, Camargo CA. Hospital length-of-stay is associated with rhinovirus etiology of bronchiolitis. Pediatr Infect Dis J. 2014 Aug; 33(8):829-34. PMID: 25222302.
      Citations: 22     Fields:    Translation:HumansCells
    123. Hasegawa K, Mansbach JM, Teach SJ, Fisher ES, Hershey D, Koh JY, Clark S, Piedra PA, Sullivan AF, Camargo CA. Multicenter study of viral etiology and relapse in hospitalized children with bronchiolitis. Pediatr Infect Dis J. 2014 Aug; 33(8):809-13. PMID: 24577039.
      Citations: 19     Fields:    Translation:HumansCells
    124. Santiago J, Mansbach JM, Chou SC, Delgado C, Piedra PA, Sullivan AF, Espinola JA, Camargo CA. Racial/ethnic differences in the presentation and management of severe bronchiolitis. J Hosp Med. 2014 Sep; 9(9):565-72. PMID: 24913444.
      Citations: 8     Fields:    Translation:Humans
    125. Piedra PA, Munoz FM. The significance of transplacental antibody against respiratory syncytial virus. J Infect Dis. 2014 Nov 15; 210(10):1526-8. PMID: 24903668.
      Citations: 1     Fields:    Translation:HumansCells
    126. Hiatt A, Bohorova N, Bohorov O, Goodman C, Kim D, Pauly MH, Velasco J, Whaley KJ, Piedra PA, Gilbert BE, Zeitlin L. Glycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacy. Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16):5992-7. PMID: 24711420.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    127. Tapia LI, Shaw CA, Aideyan LO, Jewell AM, Dawson BC, Haq TR, Piedra PA. Gene sequence variability of the three surface proteins of human respiratory syncytial virus (HRSV) in Texas. PLoS One. 2014; 9(3):e90786. PMID: 24625544.
      Citations: 19     Fields:    Translation:HumansCells
    128. Kim E, Okada K, Beeler JA, Crim RL, Piedra PA, Gilbert BE, Gambotto A. Development of an adenovirus-based respiratory syncytial virus vaccine: preclinical evaluation of efficacy, immunogenicity, and enhanced disease in a cotton rat model. J Virol. 2014 May; 88(9):5100-8. PMID: 24574396.
      Citations: 11     Fields:    Translation:AnimalsCells
    129. Wootton SH, Aguilera EA, Wanger A, Jewell A, Patel K, Murphy JR, Piedra PA. Detection of NH1N1 influenza virus in nonrespiratory sites among children. Pediatr Infect Dis J. 2014 Jan; 33(1):95-6. PMID: 24346599.
      Citations: 8     Fields:    Translation:HumansCells
    130. Hyde ER, Petrosino JF, Piedra PA, Camargo CA, Espinola JA, Mansbach JM. Nasopharyngeal Proteobacteria are associated with viral etiology and acute wheezing in children with severe bronchiolitis. J Allergy Clin Immunol. 2014 Apr; 133(4):1220-2. PMID: 24365140.
      Citations: 16     Fields:    Translation:HumansCells
    131. Ohmit SE, Thompson MG, Petrie JG, Thaker SN, Jackson ML, Belongia EA, Zimmerman RK, Gaglani M, Lamerato L, Spencer SM, Jackson L, Meece JK, Nowalk MP, Song J, Zervos M, Cheng PY, Rinaldo CR, Clipper L, Shay DK, Piedra P, Monto AS. Influenza vaccine effectiveness in the 2011-2012 season: protection against each circulating virus and the effect of prior vaccination on estimates. Clin Infect Dis. 2014 Feb; 58(3):319-27. PMID: 24235265.
      Citations: 143     Fields:    Translation:HumansCellsPHPublic Health
    132. Keitel WA, Piedra PA. Influenza A(H5N1) vaccines: are we better prepared for the next pandemic? J Infect Dis. 2014 Jan 01; 209(1):1-3. PMID: 24158956.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    133. Schroeder AR, Mansbach JM, Stevenson M, Macias CG, Fisher ES, Barcega B, Sullivan AF, Espinola JA, Piedra PA, Camargo CA. Apnea in children hospitalized with bronchiolitis. Pediatrics. 2013 Nov; 132(5):e1194-201. PMID: 24101759.
      Citations: 14     Fields:    Translation:Humans
    134. Luchsinger V, Ruiz M, Zunino E, Martínez MA, Machado C, Piedra PA, Fasce R, Ulloa MT, Fink MC, Lara P, Gebauer M, Chávez F, Avendaño LF. Community-acquired pneumonia in Chile: the clinical relevance in the detection of viruses and atypical bacteria. Thorax. 2013 Nov; 68(11):1000-6. PMID: 23783373.
      Citations: 18     Fields:    Translation:HumansCells
    135. Keitel WA, Piedra PA, Atmar RL, Demmler G, El Sahly HM, Barrett J, Halpin RA, Lagos R, Fisher-Hoch S, Munoz F. Rapid research response to the 2009 A(H1N1)pdm09 influenza pandemic (Revised). BMC Res Notes. 2013 May 03; 6:177. PMID: 23641940.
      Citations:    Fields:    Translation:HumansCells
    136. González de Dios J, Rodrigo Gonzalo de Liria C, Piedra PA, Corretger Rauet JM, Moreno-Pérez D. [Universal immunisation against influenza in paediatrics, yes or no?]. An Pediatr (Barc). 2013 Oct; 79(4):261.e1-261.e11. PMID: 23623850.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    137. Zeitlin L, Bohorov O, Bohorova N, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Barnard DL, Bates JT, Crowe JE, Piedra PA, Gilbert BE. Prophylactic and therapeutic testing of Nicotiana-derived RSV-neutralizing human monoclonal antibodies in the cotton rat model. MAbs. 2013 Mar-Apr; 5(2):263-9. PMID: 23396091.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    138. Bucasas KL, Mian AI, Demmler-Harrison GJ, Caviness AC, Piedra PA, Franco LM, Shaw CA, Zhai Y, Wang X, Bray MS, Couch RB, Belmont JW. Global gene expression profiling in infants with acute respiratory syncytial virus broncholitis demonstrates systemic activation of interferon signaling networks. Pediatr Infect Dis J. 2013 Feb; 32(2):e68-76. PMID: 23190772.
      Citations: 17     Fields:    Translation:HumansCells
    139. Mian AI, Laham FR, Cruz AT, Garg H, Macias CG, Caviness AC, Piedra PA. Nitric oxide metabolites as biomarkers for influenza-like acute respiratory infections presenting to the emergency room. Open Respir Med J. 2012; 6:127-34. PMID: 23166571.
      Citations: 4     
    140. Glenn GM, Smith G, Fries L, Raghunandan R, Lu H, Zhou B, Thomas DN, Hickman SP, Kpamegan E, Boddapati S, Piedra PA. Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine. Vaccine. 2013 Jan 07; 31(3):524-32. PMID: 23153449.
      Citations: 44     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    141. Mansbach JM, Piedra PA, Borregaard N, Martineau AR, Neuman MI, Espinola JA, Camargo CA. Serum cathelicidin level is associated with viral etiology and severity of bronchiolitis. J Allergy Clin Immunol. 2012 Oct; 130(4):1007-8.e1. PMID: 22944482.
      Citations: 19     Fields:    Translation:Humans
    142. Mansbach JM, Piedra PA, Stevenson MD, Sullivan AF, Forgey TF, Clark S, Espinola JA, Camargo CA. Prospective multicenter study of children with bronchiolitis requiring mechanical ventilation. Pediatrics. 2012 Sep; 130(3):e492-500. PMID: 22869823.
      Citations: 35     Fields:    Translation:Humans
    143. Mansbach JM, Piedra PA, Teach SJ, Sullivan AF, Forgey T, Clark S, Espinola JA, Camargo CA. Prospective multicenter study of viral etiology and hospital length of stay in children with severe bronchiolitis. Arch Pediatr Adolesc Med. 2012 Aug; 166(8):700-6. PMID: 22473882.
      Citations: 112     Fields:    Translation:HumansCells
    144. Mansbach JM, Piedra PA, Laham FR, McAdam AJ, Clark S, Sullivan AF, Camargo CA. Nasopharyngeal lactate dehydrogenase concentrations predict bronchiolitis severity in a prospective multicenter emergency department study. Pediatr Infect Dis J. 2012 Jul; 31(7):767-9. PMID: 22517336.
      Citations: 3     Fields:    Translation:Humans
    145. Luchsinger V, Piedra PA, Ruiz M, Zunino E, Martínez MA, Machado C, Fasce R, Ulloa MT, Fink MC, Lara P, Avendaño LF. Role of neutralizing antibodies in adults with community-acquired pneumonia by respiratory syncytial virus. Clin Infect Dis. 2012 Apr; 54(7):905-12. PMID: 22238168.
      Citations: 29     Fields:    Translation:HumansCells
    146. Atmar RL, Piedra PA, Patel SM, Greenberg SB, Couch RB, Glezen WP. Picornavirus, the most common respiratory virus causing infection among patients of all ages hospitalized with acute respiratory illness. J Clin Microbiol. 2012 Feb; 50(2):506-8. PMID: 22116142.
      Citations: 7     Fields:    Translation:HumansCells
    147. Glezen WP, Gaglani MJ, Kozinetz CA, Piedra PA. Direct and indirect effectiveness of influenza vaccination delivered to children at school preceding an epidemic caused by 3 new influenza virus variants. J Infect Dis. 2010 Dec 01; 202(11):1626-33. PMID: 21028955.
      Citations: 26     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    148. Paramore LC, Mahadevia PJ, Piedra PA. Outpatient RSV lower respiratory infections among high-risk infants and other pediatric populations. Pediatr Pulmonol. 2010 Jun; 45(6):578-84. PMID: 20503283.
      Citations: 5     Fields:    Translation:Humans
    149. Laham FR, Trott AA, Bennett BL, Kozinetz CA, Jewell AM, Garofalo RP, Piedra PA. LDH concentration in nasal-wash fluid as a biochemical predictor of bronchiolitis severity. Pediatrics. 2010 Feb; 125(2):e225-33. PMID: 20100751.
      Citations: 18     Fields:    Translation:Humans
    150. Piedra PA, Schulman KL, Blumentals WA. Effects of oseltamivir on influenza-related complications in children with chronic medical conditions. Pediatrics. 2009 Jul; 124(1):170-8. PMID: 19564297.
      Citations: 14     Fields:    Translation:Humans
    151. Piedra PA. Societal and economic consequences of influenza. Manag Care. 2008 Oct; 17(10 Suppl 10):8-14. PMID: 19025132.
      Citations: 2     Fields:    Translation:Humans
    152. Laham FR, Jewell AM, Schoonover SL, Demmler GJ, Piedra PA. The search for adenovirus 14 in children in Houston, Texas. Pediatr Infect Dis J. 2008 Jul; 27(7):653-4. PMID: 18520449.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    153. Kolli D, Bataki EL, Spetch L, Guerrero-Plata A, Jewell AM, Piedra PA, Milligan GN, Garofalo RP, Casola A. T lymphocytes contribute to antiviral immunity and pathogenesis in experimental human metapneumovirus infection. J Virol. 2008 Sep; 82(17):8560-9. PMID: 18562525.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    154. Gaglani MJ, Piedra PA, Riggs M, Herschler G, Fewlass C, Glezen WP. Safety of the intranasal, trivalent, live attenuated influenza vaccine (LAIV) in children with intermittent wheezing in an open-label field trial. Pediatr Infect Dis J. 2008 May; 27(5):444-52. PMID: 18401289.
      Citations: 11     Fields:    Translation:Humans
    155. Hibbert CL, Piedra PA, McLaurin KK, Vesikari T, Mauskopf J, Mahadevia PJ. Cost-effectiveness of live-attenuated influenza vaccine, trivalent in preventing influenza in young children attending day-care centres. Vaccine. 2007 Nov 19; 25(47):8010-20. PMID: 17936446.
      Citations: 13     Fields:    Translation:HumansCells
    156. Piedra PA, Gaglani MJ, Kozinetz CA, Herschler GB, Fewlass C, Harvey D, Zimmerman N, Glezen WP. Trivalent live attenuated intranasal influenza vaccine administered during the 2003-2004 influenza type A (H3N2) outbreak provided immediate, direct, and indirect protection in children. Pediatrics. 2007 Sep; 120(3):e553-64. PMID: 17698577.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    157. Bennett BL, Garofalo RP, Cron SG, Hosakote YM, Atmar RL, Macias CG, Piedra PA. Immunopathogenesis of respiratory syncytial virus bronchiolitis. J Infect Dis. 2007 May 15; 195(10):1532-40. PMID: 17436234.
      Citations: 45     Fields:    Translation:HumansCells
    158. Blutt SE, Matson DO, Crawford SE, Staat MA, Azimi P, Bennett BL, Piedra PA, Conner ME. Rotavirus antigenemia in children is associated with viremia. PLoS Med. 2007 Apr; 4(4):e121. PMID: 17439294.
      Citations: 42     Fields:    Translation:HumansCells
    159. Halloran ME, Piedra PA, Longini IM, Gaglani MJ, Schmotzer B, Fewlass C, Herschler GB, Glezen WP. Efficacy of trivalent, cold-adapted, influenza virus vaccine against influenza A (Fujian), a drift variant, during 2003-2004. Vaccine. 2007 May 16; 25(20):4038-45. PMID: 17395338.
      Citations: 17     Fields:    Translation:HumansCells
    160. Garcia DF, Hiatt PW, Jewell A, Schoonover SL, Cron SG, Riggs M, Grace S, Oermann CM, Piedra PA. Human metapneumovirus and respiratory syncytial virus infections in older children with cystic fibrosis. Pediatr Pulmonol. 2007 Jan; 42(1):66-74. PMID: 17123316.
      Citations: 13     Fields:    Translation:HumansCells
    161. Piedra PA, Gaglani MJ, Riggs M, Herschler G, Fewlass C, Watts M, Kozinetz C, Hessel C, Glezen WP. Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a community-based, nonrandomized, open-label trial. Pediatrics. 2005 Sep; 116(3):e397-407. PMID: 16140685.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    162. Beckham JD, Cadena A, Lin J, Piedra PA, Glezen WP, Greenberg SB, Atmar RL. Respiratory viral infections in patients with chronic, obstructive pulmonary disease. J Infect. 2005 May; 50(4):322-30. PMID: 15845430.
      Citations: 70     Fields:    Translation:HumansCells
    163. Piedra PA. Adenovirus in the neonatal intensive care unit: formidable, forgotten foe. J Pediatr. 2005 Apr; 146(4):447-8. PMID: 15812443.
      Citations:    Fields:    Translation:HumansCells
    164. Wyde PR, Chetty SN, Jewell AM, Schoonover SL, Piedra PA. Development of a cotton rat-human metapneumovirus (hMPV) model for identifying and evaluating potential hMPV antivirals and vaccines. Antiviral Res. 2005 Apr; 66(1):57-66. PMID: 15781133.
      Citations: 19     Fields:    Translation:AnimalsCells
    165. Piedra PA, Gaglani MJ, Kozinetz CA, Herschler G, Riggs M, Griffith M, Fewlass C, Watts M, Hessel C, Cordova J, Glezen WP. Herd immunity in adults against influenza-related illnesses with use of the trivalent-live attenuated influenza vaccine (CAIV-T) in children. Vaccine. 2005 Feb 18; 23(13):1540-8. PMID: 15694506.
      Citations: 62     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    166. Greenberg HB, Piedra PA. Immunization against viral respiratory disease: a review. Pediatr Infect Dis J. 2004 Nov; 23(11 Suppl):S254-61. PMID: 15577581.
      Citations: 7     Fields:    Translation:Humans
    167. Leen AM, Sili U, Vanin EF, Jewell AM, Xie W, Vignali D, Piedra PA, Brenner MK, Rooney CM. Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells. Blood. 2004 Oct 15; 104(8):2432-40. PMID: 15265797.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    168. Wyde PR, Moylett EH, Chetty SN, Jewell A, Bowlin TL, Piedra PA. Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by NMSO3 in tissue culture assays. Antiviral Res. 2004 Jul; 63(1):51-9. PMID: 15196820.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    169. Glezen WP, Piedra PA, Longini IM, Halloran ME. Safety of cold-adapted live influenza vaccine. Pediatr Infect Dis J. 2004 Jun; 23(6):593-4; author reply 594. PMID: 15194854.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    170. Gaglani MJ, Piedra PA, Herschler GB, Griffith ME, Kozinetz CA, Riggs MW, Fewlass C, Halloran ME, Longini IM, Glezen WP. Direct and total effectiveness of the intranasal, live-attenuated, trivalent cold-adapted influenza virus vaccine against the 2000-2001 influenza A(H1N1) and B epidemic in healthy children. Arch Pediatr Adolesc Med. 2004 Jan; 158(1):65-73. PMID: 14706961.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    171. Leen AM, Sili U, Savoldo B, Jewell AM, Piedra PA, Brenner MK, Rooney CM. Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications. Blood. 2004 Feb 01; 103(3):1011-9. PMID: 14525768.
      Citations: 34     Fields:    Translation:HumansCells
    172. Kim YJ, Hong JY, Lee HJ, Shin SH, Kim YK, Inada T, Hashido M, Piedra PA. Genome type analysis of adenovirus types 3 and 7 isolated during successive outbreaks of lower respiratory tract infections in children. J Clin Microbiol. 2003 Oct; 41(10):4594-9. PMID: 14532188.
      Citations: 41     Fields:    Translation:HumansCellsPHPublic Health
    173. Wyde PR, Chetty SN, Jewell AM, Boivin G, Piedra PA. Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro. Antiviral Res. 2003 Sep; 60(1):51-9. PMID: 14516921.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    174. Halloran ME, Longini IM, Gaglani MJ, Piedra PA, Chu H, Herschler GB, Glezen WP. Estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (CAIV-T) against influenza A (H1N1) and B using surveillance cultures. Am J Epidemiol. 2003 Aug 15; 158(4):305-11. PMID: 12915495.
      Citations: 26     Fields:    Translation:HumansCellsPHPublic Health
    175. Munoz FM, Piedra PA, Glezen WP. Safety and immunogenicity of respiratory syncytial virus purified fusion protein-2 vaccine in pregnant women. Vaccine. 2003 Jul 28; 21(24):3465-7. PMID: 12850361.
      Citations: 66     Fields:    Translation:HumansCTClinical Trials
    176. Piedra PA, Jewell AM, Cron SG, Atmar RL, Glezen WP. Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies. Vaccine. 2003 Jul 28; 21(24):3479-82. PMID: 12850364.
      Citations: 83     Fields:    Translation:HumansCells
    177. Piedra PA, Cron SG, Jewell A, Hamblett N, McBride R, Palacio MA, Ginsberg R, Oermann CM, Hiatt PW. Immunogenicity of a new purified fusion protein vaccine to respiratory syncytial virus: a multi-center trial in children with cystic fibrosis. Vaccine. 2003 Jun 02; 21(19-20):2448-60. PMID: 12744878.
      Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
    178. Piedra PA. Clinical experience with respiratory syncytial virus vaccines. Pediatr Infect Dis J. 2003 Feb; 22(2 Suppl):S94-9. PMID: 12671459.
      Citations: 18     Fields:    Translation:HumansCellsPHPublic Health
    179. Piedra PA, Yan L, Kotloff K, Zangwill K, Bernstein DI, King J, Treanor J, Munoz F, Wolff M, Cho I, Mendelman PM, Cordova J, Belshe RB. Safety of the trivalent, cold-adapted influenza vaccine in preschool-aged children. Pediatrics. 2002 Oct; 110(4):662-72. PMID: 12359778.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    180. Piedra PA. Future directions in vaccine prevention of respiratory syncytial virus. Pediatr Infect Dis J. 2002 May; 21(5):482-7. PMID: 12150197.
      Citations: 1     Fields:    Translation:Humans
    181. Piedra PA. Safety of the trivalent, cold-adapted influenza vaccine (CAIV-T) in children. Semin Pediatr Infect Dis. 2002 Apr; 13(2):90-6. PMID: 12122958.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    182. Yotnda P, Chen DH, Chiu W, Piedra PA, Davis A, Templeton NS, Brenner MK. Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther. 2002 Mar; 5(3):233-41. PMID: 11863412.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    183. Morral N, O'Neal WK, Rice K, Leland MM, Piedra PA, Aguilar-Córdova E, Carey KD, Beaudet AL, Langston C. Lethal toxicity, severe endothelial injury, and a threshold effect with high doses of an adenoviral vector in baboons. Hum Gene Ther. 2002 Jan 01; 13(1):143-54. PMID: 11779418.
      Citations: 58     Fields:    Translation:AnimalsCells
    184. Kim IH, Józkowicz A, Piedra PA, Oka K, Chan L. Lifetime correction of genetic deficiency in mice with a single injection of helper-dependent adenoviral vector. Proc Natl Acad Sci U S A. 2001 Nov 06; 98(23):13282-7. PMID: 11687662.
      Citations: 82     Fields:    Translation:AnimalsCells
    185. Hong JY, Lee HJ, Piedra PA, Choi EH, Park KH, Koh YY, Kim WS. Lower respiratory tract infections due to adenovirus in hospitalized Korean children: epidemiology, clinical features, and prognosis. Clin Infect Dis. 2001 May 15; 32(10):1423-9. PMID: 11317242.
      Citations: 63     Fields:    Translation:HumansCells
    186. Kao YJ, Piedra PA, Larsen GL, Colasurdo GN. Induction and regulation of nitric oxide synthase in airway epithelial cells by respiratory syncytial virus. Am J Respir Crit Care Med. 2001 Feb; 163(2):532-9. PMID: 11179135.
      Citations: 19     Fields:    Translation:HumansCells
    187. Mbawuike IN, Wells J, Byrd R, Cron SG, Glezen WP, Piedra PA. HLA-restricted CD8+ cytotoxic T lymphocyte, interferon-gamma, and interleukin-4 responses to respiratory syncytial virus infection in infants and children. J Infect Dis. 2001 Mar 01; 183(5):687-96. PMID: 11181144.
      Citations: 13     Fields:    Translation:HumansCells
    188. Piedra PA. Respiratory syncytial virus vaccines: recent developments. Pediatr Infect Dis J. 2000 Aug; 19(8):805-8; discussion 809-10. PMID: 10959761.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    189. Peret TC, Hall CB, Hammond GW, Piedra PA, Storch GA, Sullender WM, Tsou C, Anderson LJ. Circulation patterns of group A and B human respiratory syncytial virus genotypes in 5 communities in North America. J Infect Dis. 2000 Jun; 181(6):1891-6. PMID: 10837167.
      Citations: 98     Fields:    Translation:HumansCells
    190. Belshe RB, Gruber WC, Mendelman PM, Mehta HB, Mahmood K, Reisinger K, Treanor J, Zangwill K, Hayden FG, Bernstein DI, Kotloff K, King J, Piedra PA, Block SL, Yan L, Wolff M. Correlates of immune protection induced by live, attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine. J Infect Dis. 2000 Mar; 181(3):1133-7. PMID: 10720541.
      Citations: 117     Fields:    Translation:HumansAnimalsCellsPHPublic HealthCTClinical Trials
    191. Belshe RB, Gruber WC, Mendelman PM, Cho I, Reisinger K, Block SL, Wittes J, Iacuzio D, Piedra P, Treanor J, King J, Kotloff K, Bernstein DI, Hayden FG, Zangwill K, Yan L, Wolff M. Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A/Sydney) not contained in the vaccine. J Pediatr. 2000 Feb; 136(2):168-75. PMID: 10657821.
      Citations: 92     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    192. Glezen WP, Greenberg SB, Atmar RL, Piedra PA, Couch RB. Impact of respiratory virus infections on persons with chronic underlying conditions. JAMA. 2000 Jan 26; 283(4):499-505. PMID: 10659876.
      Citations: 128     Fields:    Translation:Humans
    193. Morral N, O'Neal W, Rice K, Leland M, Kaplan J, Piedra PA, Zhou H, Parks RJ, Velji R, Aguilar-Córdova E, Wadsworth S, Graham FL, Kochanek S, Carey KD, Beaudet AL. Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboons. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12816-21. PMID: 10536005.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    194. Wu Y, Teng BB, Brandt ML, Piedra PA, Liu J, Chan L. Normal perinatal rise in serum cholesterol is inhibited by hepatic delivery of adenoviral vector expressing apolipoprotein B mRNA editing enzyme (Apobec1) in rabbits. J Surg Res. 1999 Jul; 85(1):148-57. PMID: 10383852.
      Citations:    Fields:    Translation:AnimalsCells
    195. Hiatt PW, Grace SC, Kozinetz CA, Raboudi SH, Treece DG, Taber LH, Piedra PA. Effects of viral lower respiratory tract infection on lung function in infants with cystic fibrosis. Pediatrics. 1999 Mar; 103(3):619-26. PMID: 10049966.
      Citations: 49     Fields:    Translation:HumansCells
    196. Munoz FM, Piedra PA, Demmler GJ. Disseminated adenovirus disease in immunocompromised and immunocompetent children. Clin Infect Dis. 1998 Nov; 27(5):1194-200. PMID: 9827268.
      Citations: 45     Fields:    Translation:HumansCells
    197. Englund J, Glezen WP, Piedra PA. Maternal immunization against viral disease. Vaccine. 1998 Aug-Sep; 16(14-15):1456-63. PMID: 9711788.
      Citations: 29     Fields:    Translation:Humans
    198. Piedra PA, Poveda GA, Ramsey B, McCoy K, Hiatt PW. Incidence and prevalence of neutralizing antibodies to the common adenoviruses in children with cystic fibrosis: implication for gene therapy with adenovirus vectors. Pediatrics. 1998 Jun; 101(6):1013-9. PMID: 9606228.
      Citations: 40     Fields:    Translation:HumansCells
    199. Belshe RB, Mendelman PM, Treanor J, King J, Gruber WC, Piedra P, Bernstein DI, Hayden FG, Kotloff K, Zangwill K, Iacuzio D, Wolff M. The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children. N Engl J Med. 1998 May 14; 338(20):1405-12. PMID: 9580647.
      Citations: 170     Fields:    Translation:HumansCellsCTClinical Trials
    200. King JC, Lagos R, Bernstein DI, Piedra PA, Kotloff K, Bryant M, Cho I, Belshe RB. Safety and immunogenicity of low and high doses of trivalent live cold-adapted influenza vaccine administered intranasally as drops or spray to healthy children. J Infect Dis. 1998 May; 177(5):1394-7. PMID: 9593032.
      Citations: 13     Fields:    Translation:HumansCells
    201. Piedra PA, Grace S, Jewell A, Spinelli S, Hogerman DA, Malinoski F, Hiatt PW. Sequential annual administration of purified fusion protein vaccine against respiratory syncytial virus in children with cystic fibrosis. Pediatr Infect Dis J. 1998 Mar; 17(3):217-24. PMID: 9535249.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    202. Drews AL, Atmar RL, Glezen WP, Baxter BD, Piedra PA, Greenberg SB. Dual respiratory virus infections. Clin Infect Dis. 1997 Dec; 25(6):1421-9. PMID: 9431390.
      Citations: 56     Fields:    Translation:Humans
    203. Glezen WP, Taber LH, Frank AL, Gruber WC, Piedra PA. Influenza virus infections in infants. Pediatr Infect Dis J. 1997 Nov; 16(11):1065-8. PMID: 9384341.
      Citations: 47     Fields:    Translation:HumansPHPublic Health
    204. Englund JA, Piedra PA, Whimbey E. Prevention and treatment of respiratory syncytial virus and parainfluenza viruses in immunocompromised patients. Am J Med. 1997 Mar 17; 102(3A):61-70; discussion 75-6. PMID: 10868145.
      Citations: 7     Fields:    Translation:HumansCells
    205. Mbawuike IN, Piedra PA, Cate TR, Couch RB. Cytotoxic T lymphocyte responses of infants after natural infection or immunization with live cold-recombinant or inactivated influenza A virus vaccine. J Med Virol. 1996 Oct; 50(2):105-11. PMID: 8915874.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    206. Englund JA, Piedra PA, Jewell A, Patel K, Baxter BB, Whimbey E. Rapid diagnosis of respiratory syncytial virus infections in immunocompromised adults. J Clin Microbiol. 1996 Jul; 34(7):1649-53. PMID: 8784563.
      Citations: 43     Fields:    Translation:HumansCells
    207. Lee HJ, Pyo JW, Choi EH, Ha IS, Cheong HI, Choi Y, Kasel JA, Piedra PA. Isolation of adenovirus type 7 from the urine of children with acute hemorrhagic cystitis. Pediatr Infect Dis J. 1996 Jul; 15(7):633-4. PMID: 8823863.
      Citations: 3     Fields:    Translation:HumansCells
    208. Suara RO, Piedra PA, Glezen WP, Adegbola RA, Weber M, Mulholland EK, Greenwood BM, Whittle H. Prevalence of neutralizing antibody to respiratory syncytial virus in sera from mothers and newborns residing in the Gambia and in The United States. Clin Diagn Lab Immunol. 1996 Jul; 3(4):477-9. PMID: 8807217.
      Citations: 16     Fields:    Translation:HumansCells
    209. Gruber WC, Belshe RB, King JC, Treanor JJ, Piedra PA, Wright PF, Reed GW, Anderson E, Newman F. Evaluation of live attenuated influenza vaccines in children 6-18 months of age: safety, immunogenicity, and efficacy. National Institute of Allergy and Infectious Diseases, Vaccine and Treatment Evaluation Program and the Wyeth-Ayerst ca Influenza Vaccine Investigators Group. J Infect Dis. 1996 Jun; 173(6):1313-9. PMID: 8648202.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    210. Piedra PA, Grace S, Jewell A, Spinelli S, Bunting D, Hogerman DA, Malinoski F, Hiatt PW. Purified fusion protein vaccine protects against lower respiratory tract illness during respiratory syncytial virus season in children with cystic fibrosis. Pediatr Infect Dis J. 1996 Jan; 15(1):23-31. PMID: 8684872.
      Citations: 32     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    211. Piedra PA. Influenza virus pneumonia: pathogenesis, treatment, and prevention. Semin Respir Infect. 1995 Dec; 10(4):216-23. PMID: 8668849.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    212. Whimbey E, Champlin RE, Englund JA, Mirza NQ, Piedra PA, Goodrich JM, Przepiorka D, Luna MA, Morice RC, Neumann JL, et al. Combination therapy with aerosolized ribavirin and intravenous immunoglobulin for respiratory syncytial virus disease in adult bone marrow transplant recipients. Bone Marrow Transplant. 1995 Sep; 16(3):393-9. PMID: 8535312.
      Citations: 38     Fields:    Translation:HumansCellsCTClinical Trials
    213. Piedra PA, Glezen WP, Kasel JA, Welliver RC, Jewel AM, Rayford Y, Hogerman DA, Hildreth SW, Paradiso PR. Safety and immunogenicity of the PFP vaccine against respiratory syncytial virus (RSV): the western blot assay aids in distinguishing immune responses of the PFP vaccine from RSV infection. Vaccine. 1995 Aug; 13(12):1095-101. PMID: 7491817.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    214. Englund JA, Piedra PA, Ahn YM, Gilbert BE, Hiatt P. High-dose, short-duration ribavirin aerosol therapy compared with standard ribavirin therapy in children with suspected respiratory syncytial virus infection. J Pediatr. 1994 Oct; 125(4):635-41. PMID: 7931890.
      Citations: 11     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    215. Siber GR, Leombruno D, Leszczynski J, McIver J, Bodkin D, Gonin R, Thompson CM, Walsh EE, Piedra PA, Hemming VG, et al. Comparison of antibody concentrations and protective activity of respiratory syncytial virus immune globulin and conventional immune globulin. J Infect Dis. 1994 Jun; 169(6):1368-73. PMID: 8195619.
      Citations: 37     Fields:    Translation:AnimalsCells
    216. Piedra PA, Wyde PR, Castleman WL, Ambrose MW, Jewell AM, Speelman DJ, Hildreth SW. Enhanced pulmonary pathology associated with the use of formalin-inactivated respiratory syncytial virus vaccine in cotton rats is not a unique viral phenomenon. Vaccine. 1993 Nov; 11(14):1415-23. PMID: 7508665.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    217. Piedra PA, Glezen WP, Mbawuike I, Gruber WC, Baxter BD, Boland FJ, Byrd RW, Fan LL, Lewis JK, Rhodes LJ, et al. Studies on reactogenicity and immunogenicity of attenuated bivalent cold recombinant influenza type A (CRA) and inactivated trivalent influenza virus (TI) vaccines in infants and young children. Vaccine. 1993; 11(7):718-24. PMID: 8342319.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    218. Piedra PA, Kasel JA, Norton HJ, Garcia-Prats JA, Rayford Y, Estes MK, Hull R, Baker CJ. Description of an adenovirus type 8 outbreak in hospitalized neonates born prematurely. Pediatr Infect Dis J. 1992 Jun; 11(6):460-5. PMID: 1608683.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    219. Glezen WP, Keitel WA, Taber LH, Piedra PA, Clover RD, Couch RB. Age distribution of patients with medically-attended illnesses caused by sequential variants of influenza A/H1N1: comparison to age-specific infection rates, 1978-1989. Am J Epidemiol. 1991 Feb 01; 133(3):296-304. PMID: 2000847.
      Citations: 25     Fields:    Translation:HumansCells
    220. Englund JA, Piedra PA, Jefferson LS, Wilson SZ, Taber LH, Gilbert BE. High-dose, short-duration ribavirin aerosol therapy in children with suspected respiratory syncytial virus infection. J Pediatr. 1990 Aug; 117(2 Pt 1):313-20. PMID: 2380833.
      Citations: 14     Fields:    Translation:HumansCells
    221. Piedra PA, Kasel JA, Norton HJ, Gruber WC, Garcia-Prats JA, Baker CJ. Evaluation of an intravenous immunoglobulin preparation for the prevention of viral infection among hospitalized low birth weight infants. Pediatr Infect Dis J. 1990 Jul; 9(7):470-5. PMID: 2164655.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    222. Piedra PA, Dryja DM, LaScolea LJ. Incidence of catheter-associated gram-negative bacteremia in children with short bowel syndrome. J Clin Microbiol. 1989 Jun; 27(6):1317-9. PMID: 2666441.
      Citations: 7     Fields:    Translation:HumansCells
    223. Piedra PA, Camussi G, Ogra PL. Immune response to experimentally induced infection with respiratory syncytial virus: possible role in the development of pulmonary disease. J Gen Virol. 1989 Feb; 70 ( Pt 2):325-33. PMID: 2732693.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    224. Piedra PA, Faden HS, Camussi G, Wong DT, Ogra PL. Mechanism of lung injury in cotton rats immunized with formalin-inactivated respiratory syncytial virus. Vaccine. 1989 Feb; 7(1):34-8. PMID: 2655343.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    225. Freihorst J, Piedra PA, Okamoto Y, Ogra PL. Effect of respiratory syncytial virus infection on the uptake of and immune response to other inhaled antigens. Proc Soc Exp Biol Med. 1988 Jun; 188(2):191-7. PMID: 3375265.
      Citations: 6     Translation:AnimalsCells
    226. Leibovitz E, Freihorst J, Piedra PA, Ogra PL. Modulation of systemic and mucosal immune responses to inhaled ragweed antigen in experimentally induced infection with respiratory syncytial virus implication in virally induced allergy. Int Arch Allergy Appl Immunol. 1988; 86(1):112-6. PMID: 3372039.
      Citations: 11     Fields:    Translation:AnimalsCells
    227. Piedra P, Ogra PL. Immunologic aspects of surface infections in the lung. J Pediatr. 1986 May; 108(5 Pt 2):817-23. PMID: 3084749.
      Citations: 6     Fields:    Translation:HumansCells
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