TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address3517 Cullen Blvd
Houston, TX 77204-5056
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    R33AI122418     (FENG, QIN)Aug 13, 2018 - Nov 30, 2021
    An epigenomic approach to reactivate latent HIV
    Role: Principal Investigator

    R33AI133697     (FENG, QIN)Aug 1, 2017 - Jul 31, 2022
    Silencing of HIV-1 proviruses by epigenetically targeting transcriptional elongation
    Role: Principal Investigator

    R61AI133697     (FENG, QIN)Aug 1, 2017 - Jul 31, 2020
    Silencing of HIV-1 proviruses by epigenetically targeting transcriptional elongation
    Role: Principal Investigator

    R21AI122418     (FENG, QIN)Dec 8, 2015 - Nov 30, 2017
    An epigenomic approach to reactivate latent HIV
    Role: Principal Investigator

    K01DK084209     (FENG, QIN)Jul 1, 2009 - May 31, 2013
    CARM1 Function in Hepatic Lipid and Glucose Metabolism
    Role: Principal Investigator

    F32DK078473     (FENG, QIN)Apr 1, 2007 - Mar 31, 2009
    Regulation of a dual functional nuclear receptor coactivator CARM1
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Premaratne A, Basu S, Bagchi A, Zhou T, Feng Q, Lin CY. Liver X Receptor Ligand GAC0001E5 Downregulates Antioxidant Capacity and ERBB2/HER2 Expression in HER2-Positive Breast Cancer Cells. Cancers (Basel). 2024 Apr 25; 16(9). PMID: 38730603; PMCID: PMC11083021.
    2. Mitra A, Barua A, Huang L, Ganguly S, Feng Q, He B. From bench to bedside: the history and progress of CAR T cell therapy. Front Immunol. 2023; 14:1188049. PMID: 37256141; PMCID: PMC10225594.
      Citations: 19     Fields:    Translation:HumansCells
    3. Kim H, Barua A, Huang L, Zhou T, Bolaji M, Zachariah S, Mitra A, Jung SY, He B, Feng Q. The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with the snRNP biogenesis machinery. Oncogene. 2023 06; 42(22):1821-1831. PMID: 37041411.
      Citations:    Fields:    Translation:HumansCells
    4. Feng Q, Kim H, Barua A, Huang L, Bolaji M, Zachariah S, Jung SY, He B, Zhou T, Mitra A. The cancer testis antigen TDRD1 regulates prostate cancer proliferation by associating with snRNP biogenesis machinery. Res Sq. 2023 Feb 22. PMID: 36865141; PMCID: PMC9980208.
    5. Zhou T, Feng Q. Androgen receptor signaling and spatial chromatin organization in castration-resistant prostate cancer. Front Med (Lausanne). 2022; 9:924087. PMID: 35966880; PMCID: PMC9372301.
    6. Nikolai BC, Jain P, Cardenas DL, York B, Feng Q, McKenna NJ, Dasgupta S, Lonard DM, O'Malley BW. Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs. Sci Rep. 2021 02 09; 11(1):3441. PMID: 33564037; PMCID: PMC7873281.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    7. Gao Y, Chen L, Han Y, Wu F, Yang WS, Zhang Z, Huo T, Zhu Y, Yu C, Kim H, Lee M, Tang Z, Phillips K, He B, Jung SY, Song Y, Zhu B, Xu RM, Feng Q. Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol. 2020 04 07; 3(1):165. PMID: 32265480; PMCID: PMC7138820.
      Citations: 11     Translation:HumansCells
    8. Fu X, Pereira R, De Angelis C, Veeraraghavan J, Nanda S, Qin L, Cataldo ML, Sethunath V, Mehravaran S, Gutierrez C, Chamness GC, Feng Q, O'Malley BW, Selenica P, Weigelt B, Reis-Filho JS, Cohen O, Wagle N, Nardone A, Jeselsohn R, Brown M, Rimawi MF, Osborne CK, Schiff R. FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer. Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52):26823-26834. PMID: 31826955; PMCID: PMC6936436.
      Citations: 34     Fields:    
    9. Feng Q, He B. Androgen Receptor Signaling in the Development of Castration-Resistant Prostate Cancer. Front Oncol. 2019; 9:858. PMID: 31552182; PMCID: PMC6738163.
      Citations: 46     
    10. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Sep 19; 45(16):9348-9360. PMID: 28637181; PMCID: PMC5766202.
      Citations: 24     Fields:    Translation:HumansCells
    11. Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Mol Cell. 2017 Sep 07; 67(5):733-743.e4. PMID: 28844863; PMCID: PMC5657569.
      Citations: 33     Fields:    Translation:HumansCells
    12. Nikolai BC, Feng Q. HIV Latency Gets a New Histone Mark. Cell Host Microbe. 2017 May 10; 21(5):549-550. PMID: 28494231; PMCID: PMC6484844.
      Citations: 3     Fields:    Translation:HumansCells
    13. Xiao L, Feng Q, Zhang Z, Wang F, Lydon JP, Ittmann MM, Xin L, Mitsiades N, He B. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016 Jul 26; 7(30):47891-47903. PMID: 27374105; PMCID: PMC5216986.
      Citations: 9     Fields:    Translation:HumansAnimals
    14. Zhang Z, Lanz RB, Xiao L, Wang L, Hartig SM, Ittmann MM, Feng Q, He B. The tumor suppressive miR-200b subfamily is an ERG target gene in human prostate tumors. Oncotarget. 2016 Jun 21; 7(25):37993-38003. PMID: 27191272; PMCID: PMC5122366.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    15. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The Germ Cell Gene TDRD1 as an ERG Target Gene and a Novel Prostate Cancer Biomarker. Prostate. 2016 10; 76(14):1271-84. PMID: 27272765.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    16. Yi P, Feng Q, Foulds CE, Lanz RB, O'Malley BW, Wang Z, Pintilie GD, Ludtke SJ, Schmid MF, Chiu W. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-1058. PMID: 25728767; PMCID: PMC4369429.
      Citations: 61     Fields:    Translation:HumansCells
    17. He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18261-6. PMID: 25489091; PMCID: PMC4280633.
      Citations: 55     Fields:    Translation:HumansCells
    18. Feng Q, O'Malley BW. Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions. Steroids. 2014 Nov; 90:39-43. PMID: 24945111; PMCID: PMC4192004.
      Citations: 13     Fields:    Translation:HumansAnimals
    19. Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, Osborne CK, Schiff R, O'Malley BW. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014 Jul; 24(7):809-19. PMID: 24874954; PMCID: PMC4085766.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    20. Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O'Malley BW. Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99. PMID: 23850489; PMCID: PMC3900250.
      Citations: 73     Fields:    Translation:HumansCells
    21. Hartig SM, Feng Q, Ochsner SA, Xiao R, McKenna NJ, McGuire SE, He B. Androgen receptor agonism promotes an osteogenic gene program in preadipocytes. Biochem Biophys Res Commun. 2013 May 03; 434(2):357-62. PMID: 23567971; PMCID: PMC3763992.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    22. He B, Kim TH, Kommagani R, Feng Q, Lanz RB, Jeong JW, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011 Mar; 152(3):1047-56. PMID: 21209023; PMCID: PMC3040048.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    23. Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174. PMID: 19843527; PMCID: PMC2794732.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    24. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76. PMID: 18313384; PMCID: PMC2293272.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    25. He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60. PMID: 17932104; PMCID: PMC2234581.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    26. Wu RC, Feng Q, Lonard DM, O'Malley BW. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell. 2007 Jun 15; 129(6):1125-40. PMID: 17574025.
      Citations: 124     Fields:    Translation:HumansCells
    27. Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell. 2007 Mar 09; 25(5):765-78. PMID: 17349961; PMCID: PMC1864954.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    28. Fielenbach N, Guardavaccaro D, Neubert K, Chan T, Li D, Feng Q, Hutter H, Pagano M, Antebi A. DRE-1: an evolutionarily conserved F box protein that regulates C. elegans developmental age. Dev Cell. 2007 Mar; 12(3):443-55. PMID: 17336909.
      Citations: 37     Fields:    Translation:AnimalsCells
    29. Feng Q, Yi P, Wong J, O'Malley BW. Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol. 2006 Nov; 26(21):7846-57. PMID: 16923966; PMCID: PMC1636757.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    30. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92. PMID: 16439211.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
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