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STEEN PEDERSEN

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Physiology & Biophysics
DivisionMolecular Physiology & Biophysics
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    F32GM010093     (PEDERSEN, STEEN E)Jun 1, 1985
    NIH/NIGMS
    LIGAND BINDING SITES OF THE ACETYLCHOLINE RECEPTOR
    Role: Principal Investigator

    R29NS028879     (PEDERSEN, STEEN E)Sep 1, 1990 - Dec 31, 1995
    NIH/NINDS
    STRUCTURE OF THE NICOTINIC ACETYLCHOLINE RECEPTOR
    Role: Principal Investigator

    K04NS001618     (PEDERSEN, STEEN E)Dec 1, 1992 - Nov 30, 1997
    NIH/NINDS
    STRUCTURE AND FUNCTION OF THE ACETYLCHOLINE RECEPTOR
    Role: Principal Investigator

    R01NS035212     (PEDERSEN, STEEN E)Jun 1, 1996 - May 31, 1999
    NIH/NINDS
    LIGAND BINDING SITES OF THE ACETYLCHOLINE RECEPTOR
    Role: Principal Investigator

    R01HL087099     (PEDERSEN, STEEN E)Apr 1, 2008 - Nov 30, 2011
    NIH/NHLBI
    Regulation of Calcium Channels by Calmodulin
    Role: Principal Investigator

    S10RR027388     (PEDERSEN, STEEN E)Apr 22, 2010 - Apr 21, 2011
    NIH/NCRR
    An Instrument for Lanthanide-Luminescence Lifetime Microscopy
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chen CA, Wang W, Pedersen SE, Raman A, Seymour ML, Ruiz FR, Xia A, van der Heijden ME, Wang L, Yin J, Lopez J, Rech ME, Lewis RA, Wu SM, Liu Z, Pereira FA, Pautler RG, Zoghbi HY, Schaaf CP. Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Hum Mol Genet. 2020 Mar 27; 29(5):705-715. PMID: 31600777.
      View in: PubMed
    2. Wong BKY, Murry JB, Ramakrishnan R, He F, Balasa A, Stinnett GR, Pedersen SE, Pautler RG, Van den Veyver IB. Maternal stress in Shank3ex4-9 mice increases pup-directed care and alters brain white matter in male offspring. PLoS One. 2019; 14(11):e0224876. PMID: 31703095.
      View in: PubMed
    3. Høgild ML, Bak AM, Pedersen SB, Rungby J, Frystyk J, Møller N, Jessen N, Jørgensen JOL. Growth hormone signaling and action in obese versus lean human subjects. Am J Physiol Endocrinol Metab. 2019 02 01; 316(2):E333-E344. PMID: 30576246.
      View in: PubMed
    4. Perez EC, Rodgers SP, Inoue T, Pedersen SE, Leasure JL, Gaber MW. Olfactory Memory Impairment Differs by Sex in a Rodent Model of Pediatric Radiotherapy. Front Behav Neurosci. 2018; 12:158. PMID: 30116180.
      View in: PubMed
    5. Sahnoune I, Inoue T, Kesler SR, Rodgers SP, Sabek OM, Pedersen SE, Zawaski JA, Nelson KH, Ris MD, Leasure JL, Gaber MW. Exercise ameliorates neurocognitive impairments in a translational model of pediatric radiotherapy. Neuro Oncol. 2018 04 09; 20(5):695-704. PMID: 29121259.
      View in: PubMed
    6. Cao Z, Balasubramanian A, Pedersen SE, Romero J, Pautler RG, Marrelli SP. TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke. Sci Rep. 2017 12 15; 7(1):17685. PMID: 29247238.
      View in: PubMed
    7. Basse AL, Isidor MS, Winther S, Skjoldborg NB, Murholm M, Andersen ES, Pedersen SB, Wolfrum C, Quistorff B, Hansen JB. Regulation of glycolysis in brown adipocytes by HIF-1a. Sci Rep. 2017 06 22; 7(1):4052. PMID: 28642579.
      View in: PubMed
    8. Kjær TN, Ornstrup MJ, Poulsen MM, Stødkilde-Jørgensen H, Jessen N, Jørgensen JOL, Richelsen B, Pedersen SB. No Beneficial Effects of Resveratrol on the Metabolic Syndrome: A Randomized Placebo-Controlled Clinical Trial. J Clin Endocrinol Metab. 2017 05 01; 102(5):1642-1651. PMID: 28182820.
      View in: PubMed
    9. Quick AP, Landstrom AP, Wang Q, Beavers DL, Reynolds JO, Barreto-Torres G, Tran V, Showell J, Philippen LE, Morris SA, Skapura D, Bos JM, Pedersen SE, Pautler RG, Ackerman MJ, Wehrens XH. Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction. JACC Basic Transl Sci. 2017 Feb; 2(1):56-67. PMID: 28393127.
      View in: PubMed
    10. Blesson CS, Schutt AK, Balakrishnan MP, Pautler RG, Pedersen SE, Sarkar P, Gonzales D, Zhu G, Marini JC, Chacko SK, Yallampalli U, Yallampalli C. Novel lean type 2 diabetic rat model using gestational low-protein programming. Am J Obstet Gynecol. 2016 Apr; 214(4):540.e1-540.e7. PMID: 26874300.
      View in: PubMed
    11. Nøhr MK, Dudele A, Poulsen MM, Ebbesen LH, Radko Y, Christensen LP, Jessen N, Richelsen B, Lund S, Pedersen SB. LPS-Enhanced Glucose-Stimulated Insulin Secretion Is Normalized by Resveratrol. PLoS One. 2016; 11(1):e0146840. PMID: 26751381.
      View in: PubMed
    12. Wamberg L, Pedersen SB, Rejnmark L, Richelsen B. Causes of Vitamin D Deficiency and Effect of Vitamin D Supplementation on Metabolic Complications in Obesity: a Review. Curr Obes Rep. 2015 Dec; 4(4):429-40. PMID: 26353882.
      View in: PubMed
    13. Mallipeddi PL, Pedersen SE, Briggs JM. Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: role of residues Y93, Y190, K145 and D200. J Mol Graph Model. 2013 Jul; 44:145-54. PMID: 23831994.
      View in: PubMed
    14. Pietraszek A, Hermansen K, Pedersen SB, Langdahl BL, Holst JJ, Gregersen S. Effects of a meal rich in medium-chain saturated fat on postprandial lipemia in relatives of type 2 diabetics. Nutrition. 2013 Jul-Aug; 29(7-8):1000-6. PMID: 23644012.
      View in: PubMed
    15. Poulsen MM, Larsen JØ, Hamilton-Dutoit S, Clasen BF, Jessen N, Paulsen SK, Kjær TN, Richelsen B, Pedersen SB. Resveratrol up-regulates hepatic uncoupling protein 2 and prevents development of nonalcoholic fatty liver disease in rats fed a high-fat diet. Nutr Res. 2012 Sep; 32(9):701-8. PMID: 23084643.
      View in: PubMed
    16. Maersk M, Belza A, Stødkilde-Jørgensen H, Ringgaard S, Chabanova E, Thomsen H, Pedersen SB, Astrup A, Richelsen B. Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study. Am J Clin Nutr. 2012 Feb; 95(2):283-9. PMID: 22205311.
      View in: PubMed
    17. Kampmann U, Christensen B, Nielsen TS, Pedersen SB, Ørskov L, Lund S, Møller N, Jessen N. GLUT4 and UBC9 protein expression is reduced in muscle from type 2 diabetic patients with severe insulin resistance. PLoS One. 2011; 6(11):e27854. PMID: 22114711.
      View in: PubMed
    18. Bendsen NT, Stender S, Szecsi PB, Pedersen SB, Basu S, Hellgren LI, Newman JW, Larsen TM, Haugaard SB, Astrup A. Effect of industrially produced trans fat on markers of systemic inflammation: evidence from a randomized trial in women. J Lipid Res. 2011 Oct; 52(10):1821-8. PMID: 21795740.
      View in: PubMed
    19. Halling DB, Georgiou DK, Black DJ, Yang G, Fallon JL, Quiocho FA, Pedersen SE, Hamilton SL. Determinants in CaV1 channels that regulate the Ca2+ sensitivity of bound calmodulin. J Biol Chem. 2009 Jul 24; 284(30):20041-51. PMID: 19473981.
      View in: PubMed
    20. Bennetzen MF, Nielsen MP, Richelsen B, Pedersen SB. Effects on food intake and blood lipids of cannabinoid receptor 1 antagonist treatment in lean rats. Obesity (Silver Spring). 2008 Nov; 16(11):2451-5. PMID: 18719671.
      View in: PubMed
    21. Lihn AS, Pedersen SB, Lund S, Richelsen B. The anti-diabetic AMPK activator AICAR reduces IL-6 and IL-8 in human adipose tissue and skeletal muscle cells. Mol Cell Endocrinol. 2008 Sep 24; 292(1-2):36-41. PMID: 18606210.
      View in: PubMed
    22. Ozsoy HZ, Sivasubramanian N, Wieder ED, Pedersen S, Mann DL. Oxidative stress promotes ligand-independent and enhanced ligand-dependent tumor necrosis factor receptor signaling. J Biol Chem. 2008 Aug 22; 283(34):23419-28. PMID: 18544535.
      View in: PubMed
    23. Paulsen SK, Nielsen MP, Richelsen B, Bruun JM, Flyvbjerg A, Pedersen SB. Upregulation of adipose 11-beta-hydroxysteroid dehydrogenase type 1 expression in ovariectomized rats is due to obesity rather than lack of estrogen. Obesity (Silver Spring). 2008 Apr; 16(4):731-5. PMID: 18379559.
      View in: PubMed
    24. Zhang X, Andrews JN, Pedersen SE. Kinetic modeling and fitting software for interconnected reaction schemes: VisKin. Anal Biochem. 2007 Feb 15; 361(2):153-61. PMID: 17207764.
      View in: PubMed
    25. Meltzer RH, Lurtz MM, Wensel TG, Pedersen SE. Nicotinic acetylcholine receptor channel electrostatics determined by diffusion-enhanced luminescence energy transfer. Biophys J. 2006 Aug 15; 91(4):1315-24. PMID: 16751249.
      View in: PubMed
    26. Meltzer RH, Thompson E, Soman KV, Song XZ, Ebalunode JO, Wensel TG, Briggs JM, Pedersen SE. Electrostatic steering at acetylcholine binding sites. Biophys J. 2006 Aug 15; 91(4):1302-14. PMID: 16751247.
      View in: PubMed
    27. Meltzer RH, Vila-Carriles W, Ebalunode JO, Briggs JM, Pedersen SE. Computed pore potentials of the nicotinic acetylcholine receptor. Biophys J. 2006 Aug 15; 91(4):1325-35. PMID: 16751248.
      View in: PubMed
    28. Andreeva IE, Nirthanan S, Cohen JB, Pedersen SE. Site specificity of agonist-induced opening and desensitization of the Torpedo californica nicotinic acetylcholine receptor. Biochemistry. 2006 Jan 10; 45(1):195-204. PMID: 16388595.
      View in: PubMed
    29. Black DJ, Halling DB, Mandich DV, Pedersen SE, Altschuld RA, Hamilton SL. Calmodulin interactions with IQ peptides from voltage-dependent calcium channels. Am J Physiol Cell Physiol. 2005 Mar; 288(3):C669-76. PMID: 15496482.
      View in: PubMed
    30. Tang W, Halling DB, Black DJ, Pate P, Zhang JZ, Pedersen S, Altschuld RA, Hamilton SL. Apocalmodulin and Ca2+ calmodulin-binding sites on the CaV1.2 channel. Biophys J. 2003 Sep; 85(3):1538-47. PMID: 12944271.
      View in: PubMed
    31. Pedersen SB, Kristensen K, Richelsen B. Anti-glucocorticoid effects of progesterone in vivo on rat adipose tissue metabolism. Steroids. 2003 Aug; 68(6):543-50. PMID: 12906939.
      View in: PubMed
    32. Song XZ, Andreeva IE, Pedersen SE. Site-selective agonist binding to the nicotinic acetylcholine receptor from Torpedo californica. Biochemistry. 2003 Apr 15; 42(14):4197-207. PMID: 12680774.
      View in: PubMed
    33. Bruun JM, Nielsen CB, Pedersen SB, Flyvbjerg A, Richelsen B. Estrogen reduces pro-inflammatory cytokines in rodent adipose tissue: studies in vivo and in vitro. Horm Metab Res. 2003 Mar; 35(3):142-6. PMID: 12734773.
      View in: PubMed
    34. Willcockson IU, Hong A, Whisenant RP, Edwards JB, Wang H, Sarkar HK, Pedersen SE. Orientation of d-tubocurarine in the muscle nicotinic acetylcholine receptor-binding site. J Biol Chem. 2002 Nov 01; 277(44):42249-58. PMID: 12196523.
      View in: PubMed
    35. Malmlöf K, Din N, Johansen T, Pedersen SB. Growth hormone affects both adiposity and voluntary food intake in old and obese female rats. Eur J Endocrinol. 2002 Jan; 146(1):121-8. PMID: 11751077.
      View in: PubMed
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