MICHAEL BROUND

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Integrative Physiology
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Vanhoutte D, Schips TG, Minerath RA, Huo J, Kavuri NSS, Prasad V, Lin SC, Bround MJ, Sargent MA, Adams CM, Molkentin JD. Thbs1 regulates skeletal muscle mass in a TGF?-Smad2/3-ATF4-dependent manner. Cell Rep. 2024 May 28; 43(5):114149. PMID: 38678560; PMCID: PMC11217783.
      Citations: 1     Fields:    Translation:AnimalsCells
    2. Bround MJ, Abay E, Huo J, Havens JR, York AJ, Bers DM, Molkentin JD. MCU-independent Ca2+ uptake mediates mitochondrial Ca2+ overload and necrotic cell death in a mouse model of Duchenne muscular dystrophy. Sci Rep. 2024 03 21; 14(1):6751. PMID: 38514795; PMCID: PMC10957967.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Huo J, Prasad V, Grimes KM, Vanhoutte D, Blair NS, Lin SC, Bround MJ, Bers DM, Molkentin JD. MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle. Cell Rep. 2023 11 28; 42(11):113465. PMID: 37976157; PMCID: PMC10842842.
      Citations: 3     Fields:    Translation:AnimalsCells
    4. Bround MJ, Havens JR, York AJ, Sargent MA, Karch J, Molkentin JD. ANT-dependent MPTP underlies necrotic myofiber death in muscular dystrophy. Sci Adv. 2023 08 25; 9(34):eadi2767. PMID: 37624892; PMCID: PMC10456852.
      Citations: 4     Fields:    Translation:Animals
    5. Bround MJ, Bers DM, Molkentin JD. A 20/20 view of ANT function in mitochondrial biology and necrotic cell death. J Mol Cell Cardiol. 2020 07; 144:A3-A13. PMID: 32454061; PMCID: PMC7483807.
      Citations:    
    6. Huo J, Lu S, Kwong JQ, Bround MJ, Grimes KM, Sargent MA, Brown ME, Davis ME, Bers DM, Molkentin JD. MCUb Induction Protects the Heart From Postischemic Remodeling. Circ Res. 2020 07 17; 127(3):379-390. PMID: 32299299; PMCID: PMC7367751.
      Citations:    
    7. Antonucci S, Di Sante M, Sileikyte J, Deveraux J, Bauer T, Bround MJ, Menab? R, Paillard M, Alanova P, Carraro M, Ovize M, Molkentin JD, Cohen M, Forte MA, Bernardi P, Di Lisa F, Murphy E. A novel class of cardioprotective small-molecule PTP inhibitors. Pharmacol Res. 2020 01; 151:104548. PMID: 31759087; PMCID: PMC8500536.
      Citations:    
    8. Karch J, Bround MJ, Khalil H, Sargent MA, Latchman N, Terada N, Peixoto PM, Molkentin JD. Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD. Sci Adv. 2019 08; 5(8):eaaw4597. PMID: 31489369; PMCID: PMC6713508.
      Citations: 59     Fields:    Translation:AnimalsCells
    9. Kwong JQ, Huo J, Bround MJ, Boyer JG, Schwanekamp JA, Ghazal N, Maxwell JT, Jang YC, Khuchua Z, Shi K, Bers DM, Davis J, Molkentin JD. The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle. JCI Insight. 2018 11 15; 3(22). PMID: 30429366; PMCID: PMC6302934.
      Citations:    
    10. Bround MJ, Wambolt R, Cen H, Asghari P, Albu RF, Han J, McAfee D, Pourrier M, Scott NE, Bohunek L, Kulpa JE, Chen SR, Fedida D, Brownsey RW, Borchers CH, Foster LJ, Mayor T, Moore ED, Allard MF, Johnson JD. Cardiac Ryanodine Receptor (Ryr2)-mediated Calcium Signals Specifically Promote Glucose Oxidation via Pyruvate Dehydrogenase. J Biol Chem. 2016 Nov 04; 291(45):23490-23505. PMID: 27621312; PMCID: PMC5095405.
      Citations:    
    11. Szabat M, Page MM, Panzhinskiy E, Skovs? S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, Han J, Fan Y, Lynn FC, Trucco M, Borchers CH, Foster LJ, Nislow C, Kieffer TJ, Johnson JD. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces ? Cell Proliferation. Cell Metab. 2016 Jan 12; 23(1):179-93. PMID: 26626461.
      Citations:    
    12. Liu Y, Wang R, Sun B, Mi T, Zhang J, Mu Y, Chen J, Bround MJ, Johnson JD, Gillis AM, Chen SR. Generation and characterization of a mouse model harboring the exon-3 deletion in the cardiac ryanodine receptor. PLoS One. 2014; 9(4):e95615. PMID: 24743769; PMCID: PMC3990712.
      Citations:    
    13. Zhang D, Wan A, Chiu AP, Wang Y, Wang F, Neumaier K, Lal N, Bround MJ, Johnson JD, Vlodavsky I, Rodrigues B. Hyperglycemia-induced secretion of endothelial heparanase stimulates a vascular endothelial growth factor autocrine network in cardiomyocytes that promotes recruitment of lipoprotein lipase. Arterioscler Thromb Vasc Biol. 2013 Dec; 33(12):2830-8. PMID: 24115032.
      Citations:    
    14. Bround MJ, Wambolt R, Luciani DS, Kulpa JE, Rodrigues B, Brownsey RW, Allard MF, Johnson JD. Cardiomyocyte ATP production, metabolic flexibility, and survival require calcium flux through cardiac ryanodine receptors in vivo. J Biol Chem. 2013 Jun 28; 288(26):18975-86. PMID: 23678000; PMCID: PMC3696672.
      Citations:    
    15. Bround MJ, Asghari P, Wambolt RB, Bohunek L, Smits C, Philit M, Kieffer TJ, Lakatta EG, Boheler KR, Moore ED, Allard MF, Johnson JD. Cardiac ryanodine receptors control heart rate and rhythmicity in adult mice. Cardiovasc Res. 2012 Dec 01; 96(3):372-80. PMID: 22869620; PMCID: PMC3500041.
      Citations:    
    16. Johnson JD, Bround MJ, White SA, Luciani DS. Nanospaces between endoplasmic reticulum and mitochondria as control centres of pancreatic ?-cell metabolism and survival. Protoplasma. 2012 Feb; 249 Suppl 1:S49-58. PMID: 22105567.
      Citations:    
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