TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1100 BATES
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Han Y, Xia G, Srisai D, Meng F, He Y, Ran Y, He Y, Farias M, Hoang G, Dietrich MO, Chen MH, Xu Y, Wu Q, T?th I. Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 2021 06 10; 12(1):3525. PMID: 34112797; PMCID: PMC8192783.
      Citations: 4     Fields:    Translation:AnimalsCells
    2. Shi Y, Zhai H, John S, Shen YT, Ran Y, Hoang G, Chen MH. Gene Expression Analysis of Environmental Temperature and High-Fat Diet-Induced Changes in Mouse Supraclavicular Brown Adipose Tissue. Cells. 2021 06 02; 10(6). PMID: 34199472; PMCID: PMC8226907.
      Citations:    Fields:    Translation:HumansAnimals
    3. Stypulkowski E, Feng Q, Joseph I, Farrell V, Flores J, Yu S, Sakamori R, Sun J, Bandyopadhyay S, Das S, Dobrowolski R, Bonder EM, Chen MH, Gao N. Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes. J Biol Chem. 2021 Jan-Jun; 296:100488. PMID: 33662399; PMCID: PMC8042397.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Kaneko K, Fu Y, Lin HY, Cordonier EL, Mo Q, Gao Y, Yao T, Naylor J, Howard V, Saito K, Xu P, Chen SS, Chen MH, Xu Y, Williams KW, Ravn P, Fukuda M. Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during overnutrition. J Clin Invest. 2019 08 12; 129(9):3786-3791. PMID: 31403469; PMCID: PMC6715359.
      Citations: 29     Fields:    Translation:AnimalsCells
    5. Wei Q, Lee JH, Wang H, Bongmba OYN, Wu CS, Pradhan G, Sun Z, Chew L, Bajaj M, Chan L, Chapkin RS, Chen MH, Sun Y. Adiponectin is required for maintaining normal body temperature in a cold environment. BMC Physiol. 2017 Oct 23; 17(1):8. PMID: 29058611; PMCID: PMC5651620.
      Citations: 11     Fields:    Translation:Animals
    6. Mo Q, Salley J, Roshan T, Baer LA, May FJ, Jaehnig EJ, Lehnig AC, Guo X, Tong Q, Nuotio-Antar AM, Shamsi F, Tseng YH, Stanford KI, Chen MH. Identification and characterization of a supraclavicular brown adipose tissue in mice. JCI Insight. 2017 Jun 02; 2(11). PMID: 28570265; PMCID: PMC5453704.
      Citations: 10     Fields:    
    7. Yu DH, Gadkari M, Zhou Q, Yu S, Gao N, Guan Y, Schady D, Roshan TN, Chen MH, Laritsky E, Ge Z, Wang H, Chen R, Westwater C, Bry L, Waterland RA, Moriarty C, Hwang C, Swennes AG, Moore SR, Shen L. Postnatal epigenetic regulation of intestinal stem cells requires DNA methylation and is guided by the microbiome. Genome Biol. 2015 Sep 30; 16:211. PMID: 26420038; PMCID: PMC4589031.
      Citations: 54     Fields:    Translation:AnimalsCells
    8. Nosavanh L, Yu DH, Jaehnig EJ, Tong Q, Shen L, Chen MH. Cell-autonomous activation of Hedgehog signaling inhibits brown adipose tissue development. Proc Natl Acad Sci U S A. 2015 Apr 21; 112(16):5069-74. PMID: 25848030; PMCID: PMC4413261.
      Citations: 21     Fields:    Translation:AnimalsCells
    9. Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-? and BMP signaling pathways. J Cell Sci. 2015 May 01; 128(9):1835-47. PMID: 25749863; PMCID: PMC4446734.
      Citations: 33     Fields:    Translation:AnimalsCells
    10. Yu DH, Waterland RA, Zhang P, Schady D, Chen MH, Guan Y, Gadkari M, Shen L. Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice. J Clin Invest. 2014 Sep; 124(9):3708-12. PMID: 25061879; PMCID: PMC4151219.
      Citations: 36     Fields:    Translation:AnimalsCells
    11. Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT. Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15; 392(2):324-33. PMID: 24886827; PMCID: PMC4106470.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    12. Zhulyn O, Li D, Deimling S, Vakili NA, Mo R, Puviindran V, Chen MH, Chuang PT, Hopyan S, Hui CC. A switch from low to high Shh activity regulates establishment of limb progenitors and signaling centers. Dev Cell. 2014 Apr 28; 29(2):241-9. PMID: 24726283.
      Citations: 32     Fields:    Translation:AnimalsCells
    13. Yu DH, Ware C, Waterland RA, Zhang J, Chen MH, Gadkari M, Kunde-Ramamoorthy G, Nosavanh LM, Shen L. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation. Mol Cell Biol. 2013 May; 33(9):1845-58. PMID: 23459939; PMCID: PMC3624169.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    14. Song H, Yao E, Lin C, Gacayan R, Chen MH, Chuang PT. Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17531-6. PMID: 23047698; PMCID: PMC3491514.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    15. Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. Genes Dev. 2009 Aug 15; 23(16):1910-28. PMID: 19684112; PMCID: PMC2725943.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    16. Wilson CW, Chen MH, Chuang PT. Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium. PLoS One. 2009; 4(4):e5182. PMID: 19365551; PMCID: PMC2664476.
      Citations: 58     Fields:    Translation:AnimalsCells
    17. Wilson CW, Nguyen CT, Chen MH, Yang JH, Gacayan R, Huang J, Chen JN, Chuang PT. Fused has evolved divergent roles in vertebrate Hedgehog signalling and motile ciliogenesis. Nature. 2009 May 07; 459(7243):98-102. PMID: 19305393; PMCID: PMC3204898.
      Citations: 68     Fields:    Translation:AnimalsCells
    18. Corbit KC, Shyer AE, Dowdle WE, Gaulden J, Singla V, Chen MH, Chuang PT, Reiter JF. Kif3a constrains beta-catenin-dependent Wnt signalling through dual ciliary and non-ciliary mechanisms. Nat Cell Biol. 2008 Jan; 10(1):70-6. PMID: 18084282.
      Citations: 274     Fields:    Translation:AnimalsCells
    19. Chen MH, Wilson CW, Chuang PT. SnapShot: hedgehog signaling pathway. Cell. 2007 Jul 27; 130(2):386. PMID: 17662951.
      Citations: 11     Fields:    Translation:Cells
    20. Mak KK, Chen MH, Day TF, Chuang PT, Yang Y. Wnt/beta-catenin signaling interacts differentially with Ihh signaling in controlling endochondral bone and synovial joint formation. Development. 2006 Sep; 133(18):3695-707. PMID: 16936073.
      Citations: 81     Fields:    Translation:AnimalsCells
    21. Chen MH, Gao N, Kawakami T, Chuang PT. Mice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic development. Mol Cell Biol. 2005 Aug; 25(16):7042-53. PMID: 16055716; PMCID: PMC1190231.
      Citations: 46     Fields:    Translation:AnimalsCells
    22. Yang SH, Shrivastav A, Kosinski C, Sharma RK, Chen MH, Berthiaume LG, Peters LL, Chuang PT, Young SG, Bergo MO. N-myristoyltransferase 1 is essential in early mouse development. J Biol Chem. 2005 May 13; 280(19):18990-5. PMID: 15753093.
      Citations: 41     Fields:    Translation:AnimalsCells
    23. Chen MH, Li YJ, Kawakami T, Xu SM, Chuang PT. Palmitoylation is required for the production of a soluble multimeric Hedgehog protein complex and long-range signaling in vertebrates. Genes Dev. 2004 Mar 15; 18(6):641-59. PMID: 15075292; PMCID: PMC387240.
      Citations: 153     Fields:    Translation:AnimalsCells
    24. Chen MH, MacGowan A, Ward S, Bavik C, Greer JJ. The activation of the retinoic acid response element is inhibited in an animal model of congenital diaphragmatic hernia. Biol Neonate. 2003; 83(3):157-61. PMID: 12660430.
      Citations: 13     Fields:    Translation:AnimalsCells
    25. Chen MH, Antoni L, Tazi-Ahnini R, Cork M, Ward SJ, B?vik CO. Identification of known and novel genes whose expression is regulated by endogenous retinoic acid during early embryonic development of the mouse. Mech Dev. 2002 Jun; 114(1-2):205-12. PMID: 12175513.
      Citations: 3     Fields:    Translation:Animals
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