Amyloid beta-Peptides

"Amyloid beta-Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Peptides generated from AMYLOID BETA-PEPTIDES PRECURSOR. An amyloid fibrillar form of these peptides is the major component of amyloid plaques found in individuals with Alzheimer's disease and in aged individuals with trisomy 21 (DOWN SYNDROME). The peptide is found predominantly in the nervous system, but there have been reports of its presence in non-neural tissue.

Descriptor ID	D016229
MeSH Number(s)	D12.644.024 D12.776.049.407.249.500 D12.776.543.039.500
Concept/Terms	Amyloid beta-Peptides Amyloid beta-Peptides Amyloid beta Peptides beta-Peptides, Amyloid Alzheimer's ABP ABP, Alzheimer's Alzheimer ABP Alzheimers ABP Alzheimer's Amyloid Fibril Protein Amyloid AD-AP AD-AP, Amyloid Amyloid AD AP beta-Amyloid Protein Protein, beta-Amyloid beta Amyloid Protein Amyloid beta-Protein Amyloid beta Protein beta-Protein, Amyloid Amyloid beta-Proteins Amyloid beta Proteins beta-Proteins, Amyloid Amyloid Fibril Protein, Alzheimer's Amyloid Protein A4 Protein A4, Amyloid Alzheimer beta-Protein Alzheimer beta Protein beta-Protein, Alzheimer Amyloid beta-Peptide Amyloid beta Peptide beta-Peptide, Amyloid

Below are MeSH descriptors whose meaning is more general than "Amyloid beta-Peptides".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Amyloid beta-Peptides [D12.644.024]
Proteins [D12.776]
Amyloid [D12.776.049]
Amyloidogenic Proteins [D12.776.049.407]
Amyloid beta-Protein Precursor [D12.776.049.407.249]
Amyloid beta-Peptides [D12.776.049.407.249.500]
Membrane Proteins [D12.776.543]
Amyloid beta-Protein Precursor [D12.776.543.039]
Amyloid beta-Peptides [D12.776.543.039.500]

Below are MeSH descriptors whose meaning is related to "Amyloid beta-Peptides".

Below are MeSH descriptors whose meaning is more specific than "Amyloid beta-Peptides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Amyloid beta-Peptides" by people in this website by year, and whether "Amyloid beta-Peptides" was a major or minor topic of these publications.

Bar chart showing 246 publications over 29 distinct years, with a maximum of 18 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	0	1
1994	3	0	3
1995	2	0	2
1996	2	0	2
1997	1	0	1
1998	2	0	2
1999	1	0	1
2000	2	0	2
2001	3	1	4
2002	7	1	8
2003	9	2	11
2004	5	0	5
2005	8	1	9
2006	6	3	9
2007	8	6	14
2008	5	3	8
2009	10	6	16
2010	10	5	15
2011	12	5	17
2012	15	0	15
2013	9	9	18
2014	13	5	18
2015	7	2	9
2016	4	4	8
2017	7	4	11
2018	10	4	14
2019	7	3	10
2020	2	4	6
2021	2	5	7

Below are the most recent publications written about "Amyloid beta-Peptides" by people in Profiles.

Patel AG, Nehete PN, Krivoshik SR, Pei X, Cho EL, Nehete BP, Ramani MD, Shao Y, Williams LE, Wisniewski T, Scholtzova H. Innate immunity stimulation via CpG oligodeoxynucleotides ameliorates Alzheimer's disease pathology in aged squirrel monkeys. Brain. 2021 08 17; 144(7):2146-2165.

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Darusman HS, Li Wern T, Sajuthi D, Schapiro SJ, Hau J. Age-related cognitive impairment is associated with low serum concentrations of testosterone and CSF levels of amyloid beta 42 in male cynomolgus monkeys (Macaca fascicularis). J Med Primatol. 2021 10; 50(5):270-272.

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Armijo E, Edwards G, Flores A, Vera J, Shahnawaz M, Moda F, Gonzalez C, Sanhueza M, Soto C. Induced Pluripotent Stem Cell-Derived Neural Precursors Improve Memory, Synaptic and Pathological Abnormalities in a Mouse Model of Alzheimer's Disease. Cells. 2021 07 16; 10(7).

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Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, Cruchaga C, Goate AA, Perrin RJ, Xiong C, Li Y, Morris JC, Snider BJ, Mummery C, Surti GM, Hannequin D, Wallon D, Berman SB, Lah JJ, Jimenez-Velazquez IZ, Roberson ED, van Dyck CH, Honig LS, Sánchez-Valle R, Brooks WS, Gauthier S, Galasko DR, Masters CL, Brosch JR, Hsiung GR, Jayadev S, Formaglio M, Masellis M, Clarnette R, Pariente J, Dubois B, Pasquier F, Jack CR, Koeppe R, Snyder PJ, Aisen PS, Thomas RG, Berry SM, Wendelberger BA, Andersen SW, Holdridge KC, Mintun MA, Yaari R, Sims JR, Baudler M, Delmar P, Doody RS, Fontoura P, Giacobino C, Kerchner GA, Bateman RJ. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nat Med. 2021 Jul; 27(7):1187-1196.

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Swanson CJ, Zhang Y, Dhadda S, Wang J, Kaplow J, Lai RYK, Lannfelt L, Bradley H, Rabe M, Koyama A, Reyderman L, Berry DA, Berry S, Gordon R, Kramer LD, Cummings JL. A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer's disease with lecanemab, an anti-Aß protofibril antibody. Alzheimers Res Ther. 2021 04 17; 13(1):80.

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Willette AA, Pappas C, Hoth N, Wang Q, Klinedinst B, Willette SA, Larsen B, Pollpeter A, Li T, Le S, Collazo-Martinez AD, Mochel JP, Allenspach K, Dantzer R. Inflammation, negative affect, and amyloid burden in Alzheimer's disease: Insights from the kynurenine pathway. Brain Behav Immun. 2021 07; 95:216-225.

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Chen F, Swartzlander DB, Ghosh A, Fryer JD, Wang B, Zheng H. Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer's disease neuropathology. Mol Neurodegener. 2021 01 31; 16(1):5.

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Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunian V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol. 2021 01 20; 80(2):102-111.

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Patrick E, Olah M, Taga M, Klein HU, Xu J, White CC, Felsky D, Agrawal S, Gaiteri C, Chibnik LB, Mostafavi S, Schneider JA, Bennett DA, Bradshaw EM, De Jager PL. A cortical immune network map identifies distinct microglial transcriptional programs associated with ß-amyloid and Tau pathologies. Transl Psychiatry. 2021 01 14; 11(1):50.

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Karanth S, Nelson PT, Katsumata Y, Kryscio RJ, Schmitt FA, Fardo DW, Cykowski MD, Jicha GA, Van Eldik LJ, Abner EL. Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults. JAMA Neurol. 2020 10 01; 77(10):1299-1307.

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