Cloning, Molecular

"Cloning, Molecular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells.

Descriptor ID	D003001
MeSH Number(s)	E05.393.220
Concept/Terms	Cloning, Molecular Cloning, Molecular Molecular Cloning

Below are MeSH descriptors whose meaning is more general than "Cloning, Molecular".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Cloning, Molecular [E05.393.220]

Below are MeSH descriptors whose meaning is more specific than "Cloning, Molecular".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cloning, Molecular" by people in this website by year, and whether "Cloning, Molecular" was a major or minor topic of these publications.

Bar chart showing 822 publications over 31 distinct years, with a maximum of 59 publications in 2001

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	5	42	47
1993	3	46	49
1994	2	51	53
1995	4	45	49
1996	4	42	46
1997	2	49	51
1998	2	49	51
1999	2	36	38
2000	1	50	51
2001	2	57	59
2002	1	52	53
2003	2	47	49
2004	7	35	42
2005	1	30	31
2006	5	21	26
2007	1	11	12
2008	1	21	22
2009	2	10	12
2010	1	15	16
2011	1	5	6
2012	0	8	8
2013	1	8	9
2014	0	5	5
2015	0	5	5
2016	1	5	6
2017	1	5	6
2018	0	1	1
2019	0	5	5
2020	3	4	7
2021	1	4	5
2022	0	2	2

Below are the most recent publications written about "Cloning, Molecular" by people in Profiles.

Lin SC, Haga K, Zeng XL, Estes MK. Generation of CRISPR-Cas9-mediated genetic knockout human intestinal tissue-derived enteroid lines by lentivirus transduction and single-cell cloning. Nat Protoc. 2022 04; 17(4):1004-1027.

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Sarrion-Perdigones A, Gonzalez Y, Venken KJT. Synthetic Assembly DNA Cloning of Multiplex Hextuple Luciferase Reporter Plasmids. Methods Mol Biol. 2022; 2524:409-432.

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Tufail MS, Liaqat I, Sadiqa A, Mushtaq M, Andleeb S, Liaqat I, Munir N, Bibi A, Zain S, Fatima N, Saleem G, Rasheed F. Cloning and over Expression Studies of Ovine Somatotropin cDNA of Kajli (sheep breed) in a Prokaryotic System. J Oleo Sci. 2021 Dec 03; 70(12):1791-1796.

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Aoki-Shioi N, Terada S, Hellinger R, Furuta Y, Gruber CW. Isolation and functional diversity of Bowman-Birk type serine proteinase inhibitors from Hyacinthus orientalis. Biochem J. 2021 03 26; 478(6):1287-1301.

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Foster J, Cheng N, Paris V, Wang L, Wang J, Wang X, Nakata PA. An Arabidopsis Oxalyl-CoA Decarboxylase, AtOXC, Is Important for Oxalate Catabolism in Plants. Int J Mol Sci. 2021 Mar 23; 22(6).

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Chen WH, Wei J, Kundu RT, Adhikari R, Liu Z, Lee J, Versteeg L, Poveda C, Keegan B, Villar MJ, de Araujo Leao AC, Rivera JA, Gillespie PM, Pollet J, Strych U, Zhan B, Hotez PJ, Bottazzi ME. Genetic modification to design a stable yeast-expressed recombinant SARS-CoV-2 receptor binding domain as a COVID-19 vaccine candidate. Biochim Biophys Acta Gen Subj. 2021 06; 1865(6):129893.

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Yu Z, Ku AF, Anglin JL, Sharma R, Ucisik MN, Faver JC, Li F, Nyshadham P, Simmons N, Sharma KL, Nagarajan S, Riehle K, Kaur G, Sankaran B, Storl-Desmond M, Palmer SS, Young DW, Kim C, Matzuk MM. Discovery and characterization of bromodomain 2-specific inhibitors of BRDT. Proc Natl Acad Sci U S A. 2021 03 02; 118(9).

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Mehta SC, Furey IM, Pemberton OA, Boragine DM, Chen Y, Palzkill T. KPC-2 ß-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate. J Biol Chem. 2021 Jan-Jun; 296:100155.

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Guo YR, Fan Y, Zhou Y, Jin M, Zhang JL, Jiang H, Holt MV, Wang T, Young NL, Wang D, Zhong W, Tao YJ. Orsay Virus CP-d Adopts a Novel ß-Bracelet Structural Fold and Incorporates into Virions as a Head Fiber. J Virol. 2020 10 14; 94(21).

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Liu Z, Kundu R, Damena S, Biter AB, Nyon MP, Chen WH, Zhan B, Strych U, Hotez PJ, Bottazzi ME. A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis. Protein Expr Purif. 2021 01; 177:105750.

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