Two-Hybrid System Techniques
"Two-Hybrid System Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Screening techniques first developed in yeast to identify genes encoding interacting proteins. Variations are used to evaluate interplay between proteins and other molecules. Two-hybrid techniques refer to analysis for protein-protein interactions, one-hybrid for DNA-protein interactions, three-hybrid interactions for RNA-protein interactions or ligand-based interactions. Reverse n-hybrid techniques refer to analysis for mutations or other small molecules that dissociate known interactions.
Descriptor ID |
D020798
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MeSH Number(s) |
E05.393.220.870 E05.601.690.650 E05.601.870
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Concept/Terms |
Two-Hybrid System Techniques- Two-Hybrid System Techniques
- Technique, Two-Hybrid System
- Techniques, Two-Hybrid System
- Two Hybrid System Techniques
- Two-Hybrid System Technique
- Two-Hybrid Method
- Method, Two-Hybrid
- Methods, Two-Hybrid
- Two Hybrid Method
- Two-Hybrid Methods
- Two-Hybrid System Technics
- Technic, Two-Hybrid System
- Technics, Two-Hybrid System
- Two Hybrid System Technics
- Two-Hybrid System Technic
- Two-Hybrid Assay
- Assay, Two-Hybrid
- Assays, Two-Hybrid
- Two Hybrid Assay
- Two-Hybrid Assays
One-Hybrid System Techniques- One-Hybrid System Techniques
- One Hybrid System Techniques
- One-Hybrid System Technique
- Technique, One-Hybrid System
- Techniques, One-Hybrid System
- One-Hybrid System Technics
- One Hybrid System Technics
- One-Hybrid System Technic
- Technic, One-Hybrid System
- Technics, One-Hybrid System
Yeast Two-Hybrid System Techniques- Yeast Two-Hybrid System Techniques
- Yeast Two Hybrid System Techniques
- Yeast Two-Hybrid System
- System, Yeast Two-Hybrid
- Systems, Yeast Two-Hybrid
- Two-Hybrid System, Yeast
- Two-Hybrid Systems, Yeast
- Yeast Two Hybrid System
- Yeast Two-Hybrid Systems
- Yeast Two-Hybrid Assay
- Assay, Yeast Two-Hybrid
- Assays, Yeast Two-Hybrid
- Two-Hybrid Assay, Yeast
- Two-Hybrid Assays, Yeast
- Yeast Two Hybrid Assay
- Yeast Two-Hybrid Assays
Three-Hybrid System Techniques- Three-Hybrid System Techniques
- Technique, Three-Hybrid System
- Techniques, Three-Hybrid System
- Three Hybrid System Techniques
- Three-Hybrid System Technique
- Tri-Hybrid System Techniques
- Technique, Tri-Hybrid System
- Techniques, Tri-Hybrid System
- Tri Hybrid System Techniques
- Tri-Hybrid System Technique
- Three-Hybrid System Technics
- Technic, Three-Hybrid System
- Technics, Three-Hybrid System
- Three Hybrid System Technics
- Three-Hybrid System Technic
Yeast Three-Hybrid System Techniques- Yeast Three-Hybrid System Techniques
- Yeast Three Hybrid System Techniques
- Yeast Three-Hybrid System
- System, Yeast Three-Hybrid
- Systems, Yeast Three-Hybrid
- Three-Hybrid System, Yeast
- Three-Hybrid Systems, Yeast
- Yeast Three Hybrid System
- Yeast Three-Hybrid Systems
- Yeast Three-Hybrid Assay
- Assay, Yeast Three-Hybrid
- Assays, Yeast Three-Hybrid
- Three-Hybrid Assay, Yeast
- Three-Hybrid Assays, Yeast
- Yeast Three Hybrid Assay
- Yeast Three-Hybrid Assays
n-Hybrid System Techniques- n-Hybrid System Techniques
- System Technique, n-Hybrid
- System Techniques, n-Hybrid
- Technique, n-Hybrid System
- Techniques, n-Hybrid System
- n Hybrid System Techniques
- n-Hybrid System Technique
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Below are MeSH descriptors whose meaning is more general than "Two-Hybrid System Techniques".
Below are MeSH descriptors whose meaning is more specific than "Two-Hybrid System Techniques".
This graph shows the total number of publications written about "Two-Hybrid System Techniques" by people in this website by year, and whether "Two-Hybrid System Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 4 | 4 |
2001 | 1 | 4 | 5 |
2002 | 0 | 2 | 2 |
2003 | 0 | 5 | 5 |
2004 | 0 | 4 | 4 |
2005 | 0 | 6 | 6 |
2006 | 0 | 3 | 3 |
2007 | 0 | 2 | 2 |
2008 | 0 | 5 | 5 |
2009 | 0 | 2 | 2 |
2010 | 0 | 3 | 3 |
2011 | 0 | 4 | 4 |
2012 | 0 | 2 | 2 |
2013 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Two-Hybrid System Techniques" by people in Profiles.
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Base-resolution stratification of cancer mutations using functional variomics. Nat Protoc. 2017 Nov; 12(11):2323-2341.
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Grc3 programs the essential endoribonuclease Las1 for specific RNA cleavage. Proc Natl Acad Sci U S A. 2017 07 11; 114(28):E5530-E5538.
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Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol. 2016 Apr 22; 12(4):863.
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Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9. Eur J Immunol. 2016 Mar; 46(3):712-24.
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Human gene-centered transcription factor networks for enhancers and disease variants. Cell. 2015 Apr 23; 161(3):661-673.
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A massive expansion of effector genes underlies gall-formation in the wheat pest Mayetiola destructor. Curr Biol. 2015 Mar 02; 25(5):613-20.
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Absent, small or homeotic 2-like protein (ASH2L) enhances the transcription of the estrogen receptor a gene through GATA-binding protein 3 (GATA3). J Biol Chem. 2014 Nov 07; 289(45):31373-81.
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Systematic identification of pathological lamin A interactors. Mol Biol Cell. 2014 May; 25(9):1493-510.
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Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity. PLoS One. 2014; 9(1):e86784.
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The amyotrophic lateral sclerosis 8 protein, VAP, is required for ER protein quality control. Hum Mol Genet. 2014 Apr 15; 23(8):1975-89.