"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
Descriptor ID |
D016875
|
MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 0 | 1 |
2000 | 0 | 2 | 2 |
2001 | 1 | 0 | 1 |
2002 | 0 | 1 | 1 |
2003 | 2 | 2 | 4 |
2004 | 0 | 1 | 1 |
2005 | 5 | 1 | 6 |
2006 | 3 | 5 | 8 |
2007 | 3 | 2 | 5 |
2008 | 2 | 3 | 5 |
2009 | 4 | 0 | 4 |
2010 | 5 | 1 | 6 |
2011 | 6 | 2 | 8 |
2012 | 3 | 4 | 7 |
2013 | 7 | 1 | 8 |
2014 | 9 | 1 | 10 |
2015 | 2 | 2 | 4 |
2016 | 7 | 2 | 9 |
2017 | 3 | 1 | 4 |
2018 | 10 | 3 | 13 |
2019 | 11 | 4 | 15 |
2020 | 4 | 1 | 5 |
2021 | 3 | 5 | 8 |
2022 | 0 | 4 | 4 |
2023 | 2 | 4 | 6 |
2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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Nonalcoholic Fatty Liver Disease and Longitudinal Change in Imaging and Plasma Biomarkers of Alzheimer Disease and Vascular Pathology. Neurology. 2024 Apr 09; 102(7):e209203.
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Neuronal MAPT expression is mediated by long-range interactions with cis-regulatory elements. Am J Hum Genet. 2024 Feb 01; 111(2):259-279.
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Association of Pathologic and Volumetric Biomarker Changes With Cognitive Decline in Clinically Normal Adults. Neurology. 2023 Dec 12; 101(24):e2533-e2544.
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Proteomics analysis of plasma from middle-aged adults identifies protein markers of dementia risk in later life. Sci Transl Med. 2023 07 19; 15(705):eadf5681.
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Tau polarizes an aging transcriptional signature to excitatory neurons and glia. Elife. 2023 May 23; 12.
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Aggregation of Disordered Proteins Associated with Neurodegeneration. Int J Mol Sci. 2023 Feb 08; 24(4).
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Evolutionarily conserved regulators of tau identify targets for new therapies. Neuron. 2023 03 15; 111(6):824-838.e7.
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Associations of the Harvard Automated Phone Task and Alzheimer's Disease Pathology in Cognitively Normal Older Adults: Preliminary Findings. J Alzheimers Dis. 2023; 94(1):217-226.
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Development of a quantitative semi-mechanistic model of Alzheimer's disease based on the amyloid/tau/neurodegeneration framework (the Q-ATN model). Alzheimers Dement. 2023 06; 19(6):2287-2297.
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A surrogate marker for very early-stage tau pathology is detectable by molecular magnetic resonance imaging. Theranostics. 2022; 12(12):5504-5521.