Cell Differentiation

"Cell Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Progressive restriction of the developmental potential and increasing specialization of function that leads to the formation of specialized cells, tissues, and organs.

Descriptor ID	D002454
MeSH Number(s)	G04.152
Concept/Terms	Cell Differentiation Cell Differentiation Differentiation, Cell Cell Differentiations Differentiations, Cell

Below are MeSH descriptors whose meaning is more general than "Cell Differentiation".

Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Differentiation [G04.152]

Below are MeSH descriptors whose meaning is related to "Cell Differentiation".

Below are MeSH descriptors whose meaning is more specific than "Cell Differentiation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cell Differentiation" by people in this website by year, and whether "Cell Differentiation" was a major or minor topic of these publications.

Bar chart showing 2374 publications over 31 distinct years, with a maximum of 141 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	2	16	18
1993	6	24	30
1994	2	21	23
1995	2	27	29
1996	3	39	42
1997	1	27	28
1998	1	35	36
1999	2	40	42
2000	4	44	48
2001	11	53	64
2002	20	65	85
2003	13	79	92
2004	23	73	96
2005	28	77	105
2006	31	68	99
2007	27	93	120
2008	31	68	99
2009	33	93	126
2010	35	96	131
2011	37	98	135
2012	35	84	119
2013	45	96	141
2014	29	83	112
2015	25	89	114
2016	22	54	76
2017	24	57	81
2018	21	66	87
2019	15	44	59
2020	19	46	65
2021	17	40	57
2022	1	14	15

Below are the most recent publications written about "Cell Differentiation" by people in Profiles.

Hofmann MC, McBeath E. Sertoli Cell-Germ Cell Interactions Within the Niche: Paracrine and Juxtacrine Molecular Communications. Front Endocrinol (Lausanne). 2022; 13:897062.

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LeBleu VS. Plasticity Enables Cooperation among Heterogeneous Cancer Cell Populations to Support Metastatic Fitness. Cancer Res. 2022 May 16; 82(10):1870-1871.

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Jen HI, Singh S, Tao L, Maunsell HR, Segil N, Groves AK. GFI1 regulates hair cell differentiation by acting as an off-DNA transcriptional co-activator of ATOH1, and a DNA-binding repressor. Sci Rep. 2022 05 12; 12(1):7793.

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Dong C, Fu S, Karvas RM, Chew B, Fischer LA, Xing X, Harrison JK, Popli P, Kommagani R, Wang T, Zhang B, Theunissen TW. A genome-wide CRISPR-Cas9 knockout screen identifies essential and growth-restricting genes in human trophoblast stem cells. Nat Commun. 2022 05 10; 13(1):2548.

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Mu-Mosley H, Ostermann L, Muftuoglu M, Vaidya A, Bonifant CL, Velasquez MP, Gottschalk S, Andreeff M. Transgenic Expression of IL15 Retains CD123-Redirected T Cells in a Less Differentiated State Resulting in Improved Anti-AML Activity in Autologous AML PDX Models. Front Immunol. 2022; 13:880108.

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Karvas RM, Khan SA, Verma S, Yin Y, Kulkarni D, Dong C, Park KM, Chew B, Sane E, Fischer LA, Kumar D, Ma L, Boon ACM, Dietmann S, Mysorekar IU, Theunissen TW. Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens. Cell Stem Cell. 2022 May 05; 29(5):810-825.e8.

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Chmielowiec J, Szlachcic WJ, Yang D, Scavuzzo MA, Wamble K, Sarrion-Perdigones A, Sabek OM, Venken KJT, Borowiak M. Human pancreatic microenvironment promotes ß-cell differentiation via non-canonical WNT5A/JNK and BMP signaling. Nat Commun. 2022 04 12; 13(1):1952.

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Junco JJ, Zorman B, Gant VU, Muñoz J, Lacorazza HD, Sumazin P, Rabin KR. CRLF2 overexpression results in reduced B-cell differentiation and upregulated E2F signaling in the Dp16 mouse model of Down syndrome. Exp Hematol. 2022 06; 110:34-38.

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Sharma R, Sahoo SS, Honda M, Granger SL, Goodings C, Sanchez L, Künstner A, Busch H, Beier F, Pruett-Miller SM, Valentine MB, Fernandez AG, Chang TC, Géli V, Churikov D, Hirschi S, Pastor VB, Boerries M, Lauten M, Kelaidi C, Cooper MA, Nicholas S, Rosenfeld JA, Polychronopoulou S, Kannengiesser C, Saintomé C, Niemeyer CM, Revy P, Wold MS, Spies M, Erlacher M, Coulon S, Wlodarski MW. Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue. Blood. 2022 02 17; 139(7):1039-1051.

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Morales-Mantilla DE, Kain B, Le D, Flores AR, Paust S, King KY. Hematopoietic stem and progenitor cells improve survival from sepsis by boosting immunomodulatory cells. Elife. 2022 02 15; 11.

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