"WT1 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isoforms encoded by the WT1 Wilms tumor suppressor gene (GENES, WILMS TUMOR) and produced by alternative splicings. They are zinc finger-containing transcription factors involved in both transactivation and repression, and are critical for normal development and function of the urogenital tract.
Descriptor ID |
D025721
|
MeSH Number(s) |
D12.776.624.776.960
|
Concept/Terms |
WT1 Proteins- WT1 Proteins
- Proteins, WT1
- WT1 Protein
- Protein, WT1
- WT1 Gene Product
- Gene Product, WT1
|
Below are MeSH descriptors whose meaning is more general than "WT1 Proteins".
Below are MeSH descriptors whose meaning is more specific than "WT1 Proteins".
This graph shows the total number of publications written about "WT1 Proteins" by people in this website by year, and whether "WT1 Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 2 | 2 |
1995 | 0 | 1 | 1 |
1996 | 0 | 3 | 3 |
1998 | 0 | 1 | 1 |
1999 | 0 | 1 | 1 |
2000 | 0 | 4 | 4 |
2001 | 1 | 0 | 1 |
2002 | 2 | 0 | 2 |
2003 | 3 | 1 | 4 |
2004 | 0 | 1 | 1 |
2005 | 4 | 3 | 7 |
2006 | 2 | 0 | 2 |
2007 | 2 | 1 | 3 |
2008 | 1 | 2 | 3 |
2010 | 3 | 0 | 3 |
2011 | 1 | 0 | 1 |
2012 | 3 | 1 | 4 |
2013 | 7 | 3 | 10 |
2014 | 1 | 0 | 1 |
2015 | 1 | 1 | 2 |
2016 | 0 | 2 | 2 |
2017 | 1 | 1 | 2 |
2018 | 0 | 1 | 1 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2021 | 2 | 0 | 2 |
2022 | 2 | 0 | 2 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "WT1 Proteins" by people in Profiles.
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Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse. Differentiation. 2024 Jul-Aug; 138:100791.
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Acquired WT1 mutations contribute to relapse of NPM1-mutated acute myeloid leukemia following allogeneic hematopoietic stem cell transplant. Bone Marrow Transplant. 2022 03; 57(3):370-376.
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Tumor suppressor function of WT1 in acute promyelocytic leukemia. Haematologica. 2022 01 01; 107(1):342-346.
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A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies. Sci Rep. 2021 11 16; 11(1):22355.
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Non-transplantable cord blood units as a source for adoptive immunotherapy of leukaemia and a paradigm of circular economy in medicine. Br J Haematol. 2021 07; 194(1):158-167.
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Distant cutaneous metastasis of malignant epithelioid mesothelioma. J Cutan Pathol. 2021 Jul; 48(7):902-907.
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Testis formation in XX individuals resulting from novel pathogenic variants in Wilms' tumor 1 (WT1) gene. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13680-13688.
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Wilm's tumor 1 promotes memory flexibility. Nat Commun. 2019 08 21; 10(1):3756.
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Efficacy of ONC201 in Desmoplastic Small Round Cell Tumor. Neoplasia. 2018 05; 20(5):524-532.
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Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: a case report. BMC Nephrol. 2017 Jul 18; 18(1):243.