"Caspase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short pro-domain caspase that plays an effector role in APOPTOSIS. It is activated by INITIATOR CASPASES such as CASPASE 9. Isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.
| Descriptor ID |
D053148
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.350.300 D08.811.277.656.300.200.126.350.300 D12.644.360.075.405.350.300 D12.776.476.075.405.350.300
|
| Concept/Terms |
Procaspase-3- Procaspase-3
- Procaspase 3
- Pro-Caspase-3
- Pro Caspase 3
|
Below are MeSH descriptors whose meaning is more general than "Caspase 3".
Below are MeSH descriptors whose meaning is more specific than "Caspase 3".
This graph shows the total number of publications written about "Caspase 3" by people in this website by year, and whether "Caspase 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 4 | 4 |
| 2002 | 0 | 4 | 4 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 8 | 8 |
| 2005 | 0 | 12 | 12 |
| 2006 | 1 | 5 | 6 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 7 | 7 |
| 2010 | 1 | 4 | 5 |
| 2011 | 1 | 3 | 4 |
| 2012 | 0 | 4 | 4 |
| 2013 | 1 | 3 | 4 |
| 2014 | 2 | 3 | 5 |
| 2015 | 1 | 8 | 9 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 2 | 3 |
| 2020 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 3" by people in Profiles.
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Changes in Oxidant Defense, Apoptosis, and Cognitive Abilities During Treatment for Childhood Leukemia. Biol Res Nurs. 2018 07; 20(4):393-402.
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NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015 Aug 06; 6:e1841.
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Transmissible cytotoxicity of multiple myeloma cells by cord blood-derived NK cells is mediated by vesicle trafficking. Cell Death Differ. 2015 Jan; 22(1):96-107.
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Small molecule ErbB inhibitors decrease proliferative signaling and promote apoptosis in philadelphia chromosome-positive acute lymphoblastic leukemia. PLoS One. 2013; 8(8):e70608.
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Metabolic regulation of CaMKII protein and caspases in Xenopus laevis egg extracts. J Biol Chem. 2013 Mar 29; 288(13):8838-48.
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Sirt1 attenuates camptothecin-induced apoptosis through caspase-3 pathway in porcine preadipocytes. Exp Cell Res. 2013 Mar 10; 319(5):670-83.
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A functional variant at the miR-885-5p binding site of CASP3 confers risk of both index and second primary malignancies in patients with head and neck cancer. FASEB J. 2013 Apr; 27(4):1404-12.
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Raloxifene inhibits growth of RT4 urothelial carcinoma cells via estrogen receptor-dependent induction of apoptosis and inhibition of proliferation. Horm Cancer. 2013 Feb; 4(1):24-35.
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Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs. Am J Physiol Regul Integr Comp Physiol. 2012 Mar 15; 302(6):R682-90.
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Mesothelin confers pancreatic cancer cell resistance to TNF-a-induced apoptosis through Akt/PI3K/NF-?B activation and IL-6/Mcl-1 overexpression. Mol Cancer. 2011 Aug 31; 10:106.