"Granulosa Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Supporting cells for the developing female gamete in the OVARY. They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle. The major functions of granulosa cells include the production of steroids and LH receptors (RECEPTORS, LH).
| Descriptor ID |
D006107
|
| MeSH Number(s) |
A05.360.319.114.630.535.200 A06.407.312.497.535.300 A11.382.812 A11.436.329
|
| Concept/Terms |
Granulosa Cells- Granulosa Cells
- Cell, Granulosa
- Cells, Granulosa
- Granulosa Cell
|
Below are MeSH descriptors whose meaning is more general than "Granulosa Cells".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cells".
This graph shows the total number of publications written about "Granulosa Cells" by people in this website by year, and whether "Granulosa Cells" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1999 | 1 | 2 | 3 |
| 2000 | 1 | 4 | 5 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 4 | 6 |
| 2003 | 5 | 8 | 13 |
| 2004 | 3 | 5 | 8 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 4 | 5 |
| 2007 | 3 | 2 | 5 |
| 2008 | 6 | 4 | 10 |
| 2009 | 5 | 2 | 7 |
| 2010 | 4 | 5 | 9 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 2 | 4 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 2 | 3 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 2 | 4 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 2 | 4 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Granulosa Cells" by people in Profiles.
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Targeted deletion of NR2F2 and VCAM1 in theca cells impacts ovarian follicular development: insights into polycystic ovary syndrome??. Biol Reprod. 2024 Apr 11; 110(4):782-797.
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Oral follicle-stimulating hormone receptor agonist affects granulosa cells differently than recombinant human FSH. Fertil Steril. 2023 11; 120(5):1061-1070.
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Markers of ovarian reserve are associated with reproductive age acceleration in granulosa cells from IVF patients. Hum Reprod. 2022 09 30; 37(10):2438-2445.
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Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation. Cells. 2022 05 05; 11(9).
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Large-scale DNA demethylation occurs in proliferating ovarian granulosa cells during mouse follicular development. Commun Biol. 2021 11 25; 4(1):1334.
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A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles. Toxicol Sci. 2020 10 01; 177(2):405-419.
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Recombinant Anti-M?llerian Hormone (rAMH) for Stalling In Vitro Granulosa Cell Replication. Reprod Sci. 2020 10; 27(10):1873-1878.
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Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation. Cell Rep. 2020 04 14; 31(2):107496.
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Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice. Development. 2019 12 02; 146(23).
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Tissue-specific progesterone receptor-chromatin binding and the regulation of progesterone-dependent gene expression. Sci Rep. 2019 08 19; 9(1):11966.