"Puromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
| Descriptor ID |
D011691
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| MeSH Number(s) |
D02.241.223.200.380 D03.633.100.759.590.138.711 D09.408.051.788 D13.570.583.138.711
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Puromycin".
Below are MeSH descriptors whose meaning is more specific than "Puromycin".
This graph shows the total number of publications written about "Puromycin" by people in this website by year, and whether "Puromycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Puromycin" by people in Profiles.
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Optimized culture of retinal ganglion cells and amacrine cells from adult mice. PLoS One. 2020; 15(12):e0242426.
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Directed differentiation of regulatory T cells from naive T cells and prevention of their inflammation-mediated instability using small molecules. Clin Exp Immunol. 2020 08; 201(2):205-221.
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Generation of highly enriched V2a interneurons from mouse embryonic stem cells. Exp Neurol. 2016 Mar; 277:305-316.
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A new method for generating high purity motoneurons from mouse embryonic stem cells. Biotechnol Bioeng. 2014 Oct; 111(10):2041-55.
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Haematopoietic stem cells require a highly regulated protein synthesis rate. Nature. 2014 May 01; 509(7498):49-54.
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Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 2006 Dec 19; 45(50):15111-9.
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Pharmacological and endogenous progestins induce vascular endothelial growth factor expression in human breast cancer cells. Int J Cancer. 2001 May 15; 92(4):469-73.
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Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells. Nature. 1998 Apr 09; 392(6676):608-11.
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Induction of apoptotic cell death in chronic lymphocytic leukemia by 2-chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine. Blood. 1993 Jan 01; 81(1):143-50.
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Estrogen regulates expression of the jun family of protooncogenes in the uterus. J Steroid Biochem Mol Biol. 1992 Feb; 41(2):113-23.