"2-Chloroadenosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
2-Chloroadenosine. A metabolically stable analog of adenosine which acts as an adenosine receptor agonist. The compound has a potent effect on the peripheral and central nervous system.
| Descriptor ID |
D015762
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| MeSH Number(s) |
D03.633.100.759.590.138.300 D13.570.583.138.300 D13.570.800.096.300
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "2-Chloroadenosine".
Below are MeSH descriptors whose meaning is more specific than "2-Chloroadenosine".
This graph shows the total number of publications written about "2-Chloroadenosine" by people in this website by year, and whether "2-Chloroadenosine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "2-Chloroadenosine" by people in Profiles.
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Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease. FASEB J. 2013 May; 27(5):2013-26.
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Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels. J Biol Chem. 2010 Mar 12; 285(11):8022-30.
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A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels. Breast Cancer Res Treat. 2010 Jun; 121(2):355-64.
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Inhibition of ATP synthase by chlorinated adenosine analogue. Biochem Pharmacol. 2009 Sep 15; 78(6):583-91.
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Synthesis and hybridization properties of RNA containing 8-chloroadenosine. Nucleosides Nucleotides Nucleic Acids. 2002; 21(8-9):599-617.
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8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells. Cancer Res. 2001 Jul 15; 61(14):5474-9.
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Inhibition of colon tumor cell growth by 8-chloro-cAMP is dependent upon its conversion to 8-chloro-adenosine. Anticancer Drugs. 1992 Oct; 3(5):485-91.
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Current strategies for treatment of acute myeloid leukemia at St Jude Children's Research Hospital. Leukemia. 1992; 6 Suppl 2:39-43.
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Metabolism and action of purine nucleoside analogs. Pharmacol Ther. 1991; 49(3):239-68.