"Ionophores" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Chemical agents that increase the permeability of biological or artificial lipid membranes to specific ions. Most ionophores are relatively small organic molecules that act as mobile carriers within membranes or coalesce to form ion permeable channels across membranes. Many are antibiotics, and many act as uncoupling agents by short-circuiting the proton gradient across mitochondrial membranes.
| Descriptor ID |
D007476
|
| MeSH Number(s) |
D27.505.519.562.374 D27.720.395
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ionophores".
Below are MeSH descriptors whose meaning is more specific than "Ionophores".
This graph shows the total number of publications written about "Ionophores" by people in this website by year, and whether "Ionophores" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ionophores" by people in Profiles.
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Trans-synaptic zinc mobilization improves social interaction in two mouse models of autism through NMDAR activation. Nat Commun. 2015 May 18; 6:7168.
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Oxidized low-density lipoprotein stimulates p53-dependent activation of proapoptotic Bax leading to apoptosis of differentiated endothelial progenitor cells. Endocrinology. 2007 May; 148(5):2085-94.
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Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling. FASEB J. 2005 Dec; 19(14):2069-71.
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Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. EMBO J. 2005 Jun 15; 24(12):2104-13.
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Concerted dephosphorylation of the transcription factor NFAT1 induces a conformational switch that regulates transcriptional activity. Mol Cell. 2000 Sep; 6(3):539-50.
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Convergence between CD98 and integrin-mediated T-lymphocyte co-stimulation. Immunology. 2000 Jan; 99(1):62-8.
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Intracellular Ca2+ homeostasis in trypomastigotes of Trypanosoma cruzi. J Eukaryot Microbiol. 1998 Jan-Feb; 45(1):80-6.
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Calcium-regulated protein tyrosine phosphorylation is required for endothelin-1 to induce prostaglandin endoperoxide synthase-2 mRNA expression and protein synthesis in mesangial cells. J Am Soc Nephrol. 1997 Jul; 8(7):1080-90.
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Mechanism of alamethicin insertion into lipid bilayers. Biophys J. 1996 Nov; 71(5):2669-79.
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A comparison of in vitro toxicity and antifungal efficacy of membrane-active drugs after liposome encapsulation. Sel Cancer Ther. 1989; 5(3):113-7.