Nerve Degeneration

"Nerve Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Descriptor ID	D009410
MeSH Number(s)	C23.550.737
Concept/Terms	Nerve Degeneration Nerve Degeneration Degeneration, Nerve Degenerations, Nerve Nerve Degenerations Neuron Degeneration Degeneration, Neuron Degenerations, Neuron Neuron Degenerations

Below are MeSH descriptors whose meaning is more general than "Nerve Degeneration".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Nerve Degeneration [C23.550.737]

Below are MeSH descriptors whose meaning is related to "Nerve Degeneration".

Below are MeSH descriptors whose meaning is more specific than "Nerve Degeneration".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nerve Degeneration" by people in this website by year, and whether "Nerve Degeneration" was a major or minor topic of these publications.

Bar chart showing 106 publications over 29 distinct years, with a maximum of 10 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	1	1	2
1993	1	1	2
1994	1	0	1
1995	0	1	1
1996	1	0	1
1997	1	1	2
1998	1	2	3
1999	1	0	1
2000	2	1	3
2001	2	3	5
2002	1	0	1
2003	2	2	4
2004	0	1	1
2005	3	1	4
2006	2	3	5
2007	5	2	7
2008	6	4	10
2009	4	0	4
2010	3	0	3
2011	3	1	4
2012	5	2	7
2013	6	1	7
2014	4	3	7
2015	1	1	2
2016	4	1	5
2017	2	0	2
2018	5	1	6
2019	1	2	3
2020	2	1	3

Below are the most recent publications written about "Nerve Degeneration" by people in Profiles.

Park L, Hochrainer K, Hattori Y, Ahn SJ, Anfray A, Wang G, Uekawa K, Seo J, Palfini V, Blanco I, Acosta D, Eliezer D, Zhou P, Anrather J, Iadecola C. Tau induces PSD95-neuronal NOS uncoupling and neurovascular dysfunction independent of neurodegeneration. Nat Neurosci. 2020 09; 23(9):1079-1089.

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Chung HL, Wangler MF, Marcogliese PC, Jo J, Ravenscroft TA, Zuo Z, Duraine L, Sadeghzadeh S, Li-Kroeger D, Schmidt RE, Pestronk A, Rosenfeld JA, Burrage L, Herndon MJ, Chen S, Shillington A, Vawter-Lee M, Hopkin R, Rodriguez-Smith J, Henrickson M, Lee B, Moser AB, Jones RO, Watkins P, Yoo T, Mar S, Choi M, Bucelli RC, Yamamoto S, Lee HK, Prada CE, Chae JH, Vogel TP, Bellen HJ. Loss- or Gain-of-Function Mutations in ACOX1 Cause Axonal Loss via Different Mechanisms. Neuron. 2020 05 20; 106(4):589-606.e6.

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Zhou Y, Song WM, Andhey PS, Swain A, Levy T, Miller KR, Poliani PL, Cominelli M, Grover S, Gilfillan S, Cella M, Ulland TK, Zaitsev K, Miyashita A, Ikeuchi T, Sainouchi M, Kakita A, Bennett DA, Schneider JA, Nichols MR, Beausoleil SA, Ulrich JD, Holtzman DM, Artyomov MN, Colonna M. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease. Nat Med. 2020 01; 26(1):131-142.

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Li X, Wang L, Cykowski M, He T, Liu T, Chakranarayan J, Rivera A, Zhao H, Powell S, Xia W, Wong STC. OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. EBioMedicine. 2020 Jan; 51:102569.

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Stay TL, Miterko LN, Arancillo M, Lin T, Sillitoe RV. In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. Dis Model Mech. 2019 12 09; 13(2).

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Hsieh YC, Guo C, Yalamanchili HK, Abreha M, Al-Ouran R, Li Y, Dammer EB, Lah JJ, Levey AI, Bennett DA, De Jager PL, Seyfried NT, Liu Z, Shulman JM. Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease. Cell Rep. 2019 10 08; 29(2):301-316.e10.

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Brown AM, Arancillo M, Lin T, Catt DR, Zhou J, Lackey EP, Stay TL, Zuo Z, White JJ, Sillitoe RV. Molecular layer interneurons shape the spike activity of cerebellar Purkinje cells. Sci Rep. 2019 02 11; 9(1):1742.

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Nakata M, Nagasaka K, Shimoda M, Takashima I, Yamamoto S. Focal brain lesions induced with ultraviolet irradiation. Sci Rep. 2018 05 22; 8(1):7968.

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Orengo JP, van der Heijden ME, Hao S, Tang J, Orr HT, Zoghbi HY. Motor neuron degeneration correlates with respiratory dysfunction in SCA1. Dis Model Mech. 2018 02 26; 11(2).

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Ogawa Y, Kakumoto K, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ. Elavl3 is essential for the maintenance of Purkinje neuron axons. Sci Rep. 2018 02 09; 8(1):2722.

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