"Wallerian Degeneration" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Degeneration of distal aspects of a nerve axon following injury to the cell body or proximal portion of the axon. The process is characterized by fragmentation of the axon and its MYELIN SHEATH.
Descriptor ID |
D014855
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MeSH Number(s) |
C23.550.737.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Wallerian Degeneration".
Below are MeSH descriptors whose meaning is more specific than "Wallerian Degeneration".
This graph shows the total number of publications written about "Wallerian Degeneration" by people in this website by year, and whether "Wallerian Degeneration" was a major or minor topic of these publications.
To see the data from this visualization as text,
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 1 | 1 | 2 |
2011 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wallerian Degeneration" by people in Profiles.
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Neuroimmune processes associated with Wallerian degeneration support neurotrophin-3-induced axonal sprouting in the injured spinal cord. J Neurosci Res. 2013 Oct; 91(10):1280-91.
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Actin polymerization is essential for myelin sheath fragmentation during Wallerian degeneration. J Neurosci. 2011 Feb 09; 31(6):2009-15.
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When, where, and how the corpus callosum changes in MCI and AD: a multimodal MRI study. Neurology. 2010 Apr 06; 74(14):1136-42.
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Sensorimotor cortex aspiration: a model for studying Wallerian degeneration-induced glial reactivity along the entire length of a single CNS axonal pathway. Brain Res Bull. 2010 Jan 15; 81(1):43-52.
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Proteasome inhibition suppresses Schwann cell dedifferentiation in vitro and in vivo. Glia. 2009 Dec; 57(16):1825-34.
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Interleukin-6 is required for the early induction of glial fibrillary acidic protein in Schwann cells during Wallerian degeneration. J Neurochem. 2009 Feb; 108(3):776-86.
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Assessing optic nerve pathology with diffusion MRI: from mouse to human. NMR Biomed. 2008 Nov; 21(9):928-40.
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Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity. PLoS Biol. 2006 Nov; 4(12):e416.
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CNP is required for maintenance of axon-glia interactions at nodes of Ranvier in the CNS. Glia. 2005 Apr 01; 50(1):86-90.
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Axon-Schwann cell interactions regulate the expression of fibroblast growth factor-5 (FGF-5). J Neurosci Res. 2001 Oct 01; 66(1):16-22.