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BOYI GAN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentExperimental Radiation Oncology
Address6565 MD Anderson Blvd
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yan Y, Zhuang L, Gan B. GPR56: GPCR as a guardian against ferroptosis. Cell Metab. 2024 Nov 05; 36(11):2355-2356. PMID: 39504935.
      Citations:    
    2. Conradt B, Miao EA, Yuan J, Kanneganti TD, Stockwell BR, Tsvetkov P, Overholtzer M, Gan B. The story behind the emergence of different forms of cell death. Dev Cell. 2024 Oct 07; 59(19):2519-2522. PMID: 39378837.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Yan Y, Gan B. Dodging death. Nat Chem Biol. 2024 Oct; 20(10):1252-1253. PMID: 38720106.
      Citations:    Fields:    
    4. Mao C, Wang M, Zhuang L, Gan B, Mao C, Gan B. Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond. Protein Cell. 2024 Sep 01; 15(9):642-660. PMID: 38428031; PMCID: PMC11365558.
      Citations: 5     Fields:    Translation:HumansAnimals
    5. Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, Horbath A, Olszewski K, Kondiparthi L, Mao C, Lee H, Zhuang L, Poyurovsky M, Stockwell BR, Chen J, Gan B, Liu X, Chen Z, Yan Y, Zandkarimi F, Nie L, Li Q, Horbath A, Olszewski K, Kondiparthi L, Mao C, Lee H, Poyurovsky M, Stockwell BR, Gan B. Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis. Protein Cell. 2024 Sep 01; 15(9):686-703. PMID: 38430542; PMCID: PMC11365556.
      Citations: 2     Fields:    Translation:HumansCells
    6. Lee H, Zhuang L, Gan B. Rewiring cancer cell death: LPCAT1 shapes lipid composition and ferroptosis resistance. Cell Death Differ. 2024 Sep; 31(9):1101-1103. PMID: 39138374; PMCID: PMC11369197.
      Citations:    Fields:    Translation:HumansAnimals
    7. Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B, Lei G, Mao C, Horbath AD, Yan Y, Cai S, Yao J, Jiang Y, Sun M, Liu X, Cheng J, Xu Z, Lee H, Li Q, Lu Z, Zhuang L, Chen MK, Alapati A, Yap TA, Hung MC, You MJ, Piwnica-Worms H, Gan B. BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer Discov. 2024 Aug 02; 14(8):1476-1495. PMID: 38552003; PMCID: PMC11296921.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    8. Mao C, Lei G, Horbath A, Wang M, Lu Z, Yan Y, Liu X, Kondiparthi L, Chen X, Cheng J, Li Q, Xu Z, Zhuang L, Fang B, Marszalek JR, Poyurovsky MV, Olszewski K, Gan B. Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers. Mol Cell. 2024 May 16; 84(10):1964-1979.e6. PMID: 38759628; PMCID: PMC11104512.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Jiang D, Guo Y, Wang T, Wang L, Yan Y, Xia L, Bam R, Yang Z, Lee H, Iwawaki T, Gan B, Koong AC. IRE1a determines ferroptosis sensitivity through regulation of glutathione synthesis. Nat Commun. 2024 May 15; 15(1):4114. PMID: 38750057; PMCID: PMC11096184.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    10. Lee H, Zhuang L, Gan B. VHL governs m6A modification and PIK3R3 mRNA stability in clear cell renal cell carcinomas. J Clin Invest. 2024 Apr 15; 134(8). PMID: 38618953; PMCID: PMC11014664.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    11. Lei G, Zhuang L, Gan B. The roles of ferroptosis in cancer: Tumor suppression, tumor microenvironment, and therapeutic interventions. Cancer Cell. 2024 Apr 08; 42(4):513-534. PMID: 38593779.
      Citations: 8     Fields:    Translation:Humans
    12. Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, Ma L, Gan B, Chen J. DePARylation is critical for S phase progression and cell survival. Elife. 2024 Apr 05; 12. PMID: 38578205; PMCID: PMC10997334.
      Citations: 3     Fields:    Translation:Cells
    13. Lei G, Gan B. Exploring Ferroptosis-Inducing Therapies for Cancer Treatment: Challenges and Opportunities. Cancer Res. 2024 Apr 01; 84(7):961-964. PMID: 38558130; PMCID: PMC10987048.
      Citations: 1     Fields:    Translation:Humans
    14. Bi G, Liang J, Bian Y, Shan G, Huang Y, Lu T, Zhang H, Jin X, Chen Z, Zhao M, Fan H, Wang Q, Gan B, Zhan C. Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer. Nat Commun. 2024 Mar 19; 15(1):2461. PMID: 38504107; PMCID: PMC10951362.
      Citations: 9     Fields:    Translation:HumansCells
    15. Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Liu J, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi JT, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. A guideline on the molecular ecosystem regulating ferroptosis. Nat Cell Biol. 2024 Sep; 26(9):1447-1457. PMID: 38424270.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    16. Chen X, Gan B. SLC25A39 links mitochondrial GSH sensing with iron metabolism. Mol Cell. 2024 Feb 15; 84(4):616-618. PMID: 38364779.
      Citations: 1     Fields:    Translation:Cells
    17. Nie L, Wang C, Huang M, Liu X, Feng X, Tang M, Li S, Hang Q, Teng H, Shen X, Gan B, Ma L, Chen J. DePARylation is critical for S phase progression and cell survival. bioRxiv. 2024 Feb 02. PMID: 37577639; PMCID: PMC10418084.
      Citations:    
    18. Lee H, Horbath A, Kondiparthi L, Meena JK, Lei G, Dasgupta S, Liu X, Zhuang L, Koppula P, Li M, Mahmud I, Wei B, Lorenzi PL, Keyomarsi K, Poyurovsky MV, Olszewski K, Gan B. Cell cycle arrest induces lipid droplet formation and confers ferroptosis resistance. Nat Commun. 2024 01 02; 15(1):79. PMID: 38167301; PMCID: PMC10761718.
      Citations: 9     Fields:    Translation:HumansCells
    19. Yan Y, Gan B. Hyperoxidized PRDX3 as a specific ferroptosis marker. Life Metab. 2023 Dec; 2(6). PMID: 38179338; PMCID: PMC10766428.
      Citations:    
    20. Huang S, Zhang Q, Zhao M, Wang X, Zhang Y, Gan B, Zhang P. The deubiquitinase ZRANB1 is an E3 ubiquitin ligase for SLC7A11 and regulates ferroptotic resistance. J Cell Biol. 2023 11 06; 222(11). PMID: 37831441; PMCID: PMC10570852.
      Citations:    Fields:    Translation:HumansCells
    21. Zhang S, Gou S, Zhang Q, Yong X, Gan B, Jia D. FSP1 oxidizes NADPH to suppress ferroptosis. Cell Res. 2023 12; 33(12):967-970. PMID: 37739993; PMCID: PMC10709417.
      Citations: 5     Fields:    
    22. Liu X, Zhuang L, Gan B. Unleashing ferroptosis for cancer therapy with warfarin. Trends Endocrinol Metab. 2023 11; 34(11):683-684. PMID: 37648560.
      Citations:    Fields:    Translation:Humans
    23. Gan B. The pyrimidinosome: Orchestrating pyrimidine biosynthesis and ferroptosis defense. Mol Cell. 2023 08 17; 83(16):2837-2839. PMID: 37595553.
      Citations:    Fields:    
    24. Liu X, Zhuang L, Gan B. Disulfidptosis: disulfide stress-induced cell death. Trends Cell Biol. 2024 Apr; 34(4):327-337. PMID: 37574347.
      Citations: 9     Fields:    
    25. Wang Z, Ouyang L, Liu N, Li T, Yan B, Mao C, Xiao D, Gan B, Liu S, Tao Y. The DUBA-SLC7A11-c-Myc axis is critical for stemness and ferroptosis. Oncogene. 2023 09; 42(36):2688-2700. PMID: 37537342.
      Citations: 1     Fields:    Translation:Humans
    26. Li Q, Gan B. Uncovering the IL-1?-PCAF-NNT axis: A new player in ferroptosis and tumor immune evasion. Cancer Commun (Lond). 2023 09; 43(9):1048-1050. PMID: 37488943; PMCID: PMC10508136.
      Citations: 1     Fields:    Translation:Humans
    27. Bi G, Liang J, Shan G, Bian Y, Chen Z, Huang Y, Lu T, Li M, Besskaya V, Zhao M, Fan H, Wang Q, Gan B, Zhan C. Retinol Saturase Mediates Retinoid Metabolism to Impair a Ferroptosis Defense System in Cancer Cells. Cancer Res. 2023 07 14; 83(14):2387-2404. PMID: 37184371.
      Citations: 1     Fields:    Translation:Humans
    28. Mao C, Liu X, Yan Y, Olszewski K, Gan B. Reply to: DHODH inhibitors sensitize to ferroptosis by FSP1 inhibition. Nature. 2023 Jul; 619(7968):E19-E23. PMID: 37407682.
      Citations: 3     Fields:    
    29. Yan Y, Teng H, Hang Q, Kondiparthi L, Lei G, Horbath A, Liu X, Mao C, Wu S, Zhuang L, James You M, Poyurovsky MV, Ma L, Olszewski K, Gan B. SLC7A11 expression level dictates differential responses to oxidative stress in cancer cells. Nat Commun. 2023 06 21; 14(1):3673. PMID: 37339981; PMCID: PMC10281978.
      Citations: 11     Fields:    Translation:Cells
    30. Zhang Y, Zhao Z, Huang LA, Liu Y, Yao J, Sun C, Li Y, Zhang Z, Ye Y, Yuan F, Nguyen TK, Garlapati NR, Wu A, Egranov SD, Caudle AS, Sahin AA, Lim B, Beretta L, Calin GA, Yu D, Hung MC, Curran MA, Rezvani K, Gan B, Tan Z, Han L, Lin C, Yang L. Molecular mechanisms of snoRNA-IL-15 crosstalk in adipocyte lipolysis and NK cell rejuvenation. Cell Metab. 2023 08 08; 35(8):1457-1473.e13. PMID: 37329887; PMCID: PMC10712687.
      Citations: 2     Fields:    Translation:AnimalsCells
    31. Lee H, Zhuang L, Gan B. Ferroptosis vulnerability in FLT3-mutant leukemia. Trends Cancer. 2023 07; 9(7):524-525. PMID: 37173186.
      Citations:    Fields:    Translation:Humans
    32. Gan B. Ferroptosis hijacking by Mycobacterium tuberculosis. Nat Commun. 2023 03 17; 14(1):1431. PMID: 36932073; PMCID: PMC10023749.
      Citations:    Fields:    Translation:HumansCells
    33. Gan B. How erastin assassinates cells by ferroptosis revealed. Protein Cell. 2023 03 16; 14(2):84-86. PMID: 36929006; PMCID: PMC10019563.
      Citations:    Fields:    Translation:Cells
    34. Liu X, Nie L, Zhang Y, Yan Y, Wang C, Colic M, Olszewski K, Horbath A, Chen X, Lei G, Mao C, Wu S, Zhuang L, Poyurovsky MV, James You M, Hart T, Billadeau DD, Chen J, Gan B. Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis. Nat Cell Biol. 2023 03; 25(3):404-414. PMID: 36747082; PMCID: PMC10027392.
      Citations: 47     Fields:    Translation:HumansCells
    35. Gan B. A Time and Place for Inhibiting Autophagy. Cancer Res. 2022 12 02; 82(23):4322-4324. PMID: 36458406; PMCID: PMC9720714.
      Citations:    Fields:    Translation:Animals
    36. Lee H, Gan B. Ferroptosis execution: Is it all about ACSL4? Cell Chem Biol. 2022 09 15; 29(9):1363-1365. PMID: 36113403.
      Citations:    
    37. Nie L, Wang C, Liu X, Teng H, Li S, Huang M, Feng X, Pei G, Hang Q, Zhao Z, Gan B, Ma L, Chen J. USP7 substrates identified by proteomics analysis reveal the specificity of USP7. Genes Dev. 2022 09 01; 36(17-18):1016-1030. PMID: 36302555; PMCID: PMC9732911.
      Citations: 3     Fields:    Translation:Cells
    38. Subbiah V, Gan B. Targeting Ferroptosis Vulnerability in Synovial Sarcoma: Is It All About ME1? Clin Cancer Res. 2022 08 15; 28(16):3408-3410. PMID: 35727698.
      Citations:    Fields:    
    39. Mao C, Gan B. Navigating ferroptosis via an NADPH sensor. Nat Cell Biol. 2022 08; 24(8):1186-1187. PMID: 35941366.
      Citations:    
    40. Dasgupta S, Gan B. Ferroptosis vulnerability in MYCN-driven neuroblastomas. Clin Transl Med. 2022 08; 12(8):e963. PMID: 35908258; PMCID: PMC9339235.
      Citations:    
    41. Mao C, Lei G, Horbath A, Gan B. Assessment of lipid peroxidation in irradiated cells. Methods Cell Biol. 2022; 172:37-50. PMID: 36064225.
      Citations:    
    42. Wu S, Mao C, Kondiparthi L, Poyurovsky MV, Olszewski K, Gan B. A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria. Proc Natl Acad Sci U S A. 2022 06 28; 119(26):e2121987119. PMID: 35749365; PMCID: PMC9245637.
      Citations:    Fields:    Translation:HumansCells
    43. Lei G, Horbath A, Li Z, Gan B. PKC?II-ACSL4 pathway mediating ferroptosis execution and anti-tumor immunity. Cancer Commun (Lond). 2022 07; 42(7):583-586. PMID: 35674490; PMCID: PMC9257991.
      Citations:    Fields:    Translation:HumansCells
    44. Gan B. ACSL4, PUFA, and ferroptosis: new arsenal in anti-tumor immunity. Signal Transduct Target Ther. 2022 04 22; 7(1):128. PMID: 35459217; PMCID: PMC9033814.
      Citations:    Fields:    Translation:Cells
    45. Koppula P, Lei G, Zhang Y, Yan Y, Mao C, Kondiparthi L, Shi J, Liu X, Horbath A, Das M, Li W, Poyurovsky MV, Olszewski K, Gan B. A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers. Nat Commun. 2022 04 22; 13(1):2206. PMID: 35459868; PMCID: PMC9033817.
      Citations: 1     Fields:    Translation:HumansCells
    46. Lei G, Zhuang L, Gan B. Targeting ferroptosis as a vulnerability in cancer. Nat Rev Cancer. 2022 07; 22(7):381-396. PMID: 35338310; PMCID: PMC10243716.
      Citations: 8     Fields:    Translation:Humans
    47. Lei G, Gan B. Iron out KRAS-driven cancer. J Exp Med. 2022 04 04; 219(4). PMID: 35262627; PMCID: PMC8919642.
      Citations:    Fields:    Translation:Humans
    48. Yao F, Deng Y, Zhao Y, Mei Y, Zhang Y, Liu X, Martinez C, Su X, Rosato RR, Teng H, Hang Q, Yap S, Chen D, Wang Y, Chen MM, Zhang M, Liang H, Xie D, Chen X, Zhu H, Chang JC, You MJ, Sun Y, Gan B, Ma L. A targetable LIFR-NF-?B-LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis. Nat Commun. 2021 12 17; 12(1):7333. PMID: 34921145; PMCID: PMC8683481.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    49. Liu X, Koppula P, Olszewski K, Gan B. Thiol profiling in cancer cell lines by HPLC-mass spectrometry. STAR Protoc. 2021 12 17; 2(4):100977. PMID: 34917974; PMCID: PMC8669100.
      Citations:    Fields:    Translation:HumansCells
    50. Mao C, Lei G, Zhuang L, Gan B. Ferroptosis as an important driver of lupus. Protein Cell. 2022 05; 13(5):313-315. PMID: 34826064; PMCID: PMC9008102.
      Citations: 2     Fields:    
    51. Mao C, Lei G, Zhuang L, Gan B. Phospholipase iPLA2? acts as a guardian against ferroptosis. Cancer Commun (Lond). 2021 11; 41(11):1082-1085. PMID: 34657380; PMCID: PMC8626608.
      Citations:    Fields:    Translation:Humans
    52. Liu X, Gan B. Glucose starvation induces NADPH collapse and disulfide stress in SLC7A11high cancer cells. Oncotarget. 2021 Aug 03; 12(16):1629-1630. PMID: 34381568; PMCID: PMC8351606.
      Citations:    Fields:    
    53. Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, Poyurovsky MV, Olszewski K, Gan B. Author Correction: DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature. 2021 Aug; 596(7873):E13. PMID: 34341547.
      Citations: 2     Fields:    
    54. Gan B. Mitochondrial regulation of ferroptosis. J Cell Biol. 2021 09 06; 220(9). PMID: 34328510; PMCID: PMC8329737.
      Citations: 14     Fields:    Translation:HumansCells
    55. Lei G, Zhuang L, Gan B. mTORC1 and ferroptosis: Regulatory mechanisms and therapeutic potential. Bioessays. 2021 08; 43(8):e2100093. PMID: 34121197.
      Citations: 5     Fields:    Translation:Cells
    56. Lee H, Zhuang L, Gan B. Ether phospholipids govern ferroptosis. J Genet Genomics. 2021 Jul 20; 48(7):517-519. PMID: 34167916; PMCID: PMC8453040.
      Citations: 2     Fields:    
    57. Koppula P, Olszewski K, Zhang Y, Kondiparthi L, Liu X, Lei G, Das M, Fang B, Poyurovsky MV, Gan B. KEAP1 deficiency drives glucose dependency and sensitizes lung cancer cells and tumors to GLUT inhibition. iScience. 2021 Jun 25; 24(6):102649. PMID: 34151236; PMCID: PMC8193145.
      Citations: 9     
    58. Mao C, Liu X, Zhang Y, Lei G, Yan Y, Lee H, Koppula P, Wu S, Zhuang L, Fang B, Poyurovsky MV, Olszewski K, Gan B. DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer. Nature. 2021 05; 593(7860):586-590. PMID: 33981038; PMCID: PMC8895686.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    59. Lei G, Zhang Y, Hong T, Zhang X, Liu X, Mao C, Yan Y, Koppula P, Cheng W, Sood AK, Liu J, Gan B. Ferroptosis as a mechanism to mediate p53 function in tumor radiosensitivity. Oncogene. 2021 05; 40(20):3533-3547. PMID: 33927351; PMCID: PMC8141034.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    60. Yan Y, Lei G, Gan B. A mTORC1-mediated cyst(e)ine sensing mechanism governing GPX4 synthesis and ferroptosis. Mol Cell Oncol. 2021; 8(3):1919006. PMID: 34027051; PMCID: PMC8128196.
      Citations: 1     
    61. Lei G, Mao C, Yan Y, Zhuang L, Gan B. Ferroptosis, radiotherapy, and combination therapeutic strategies. Protein Cell. 2021 11; 12(11):836-857. PMID: 33891303; PMCID: PMC8563889.
      Citations: 30     Fields:    Translation:Humans
    62. Zhang Y, Swanda RV, Nie L, Liu X, Wang C, Lee H, Lei G, Mao C, Koppula P, Cheng W, Zhang J, Xiao Z, Zhuang L, Fang B, Chen J, Qian SB, Gan B. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021 03 11; 12(1):1589. PMID: 33707434; PMCID: PMC7952727.
      Citations: 37     Fields:    Translation:HumansCells
    63. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almasan A, Alonso A, Altan-Bonnet N, Altieri DC, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antebi A, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araya J, Arden C, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Aroca A, Arsov I, Asaro DML, Aschner M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bao Y, Baracca A, Barbati C, Bargiela A, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC, Basu A, Batoko H, Batten I, Baumgarner BL, Beale R, Bechara LRG, Beck GR, Beers MF, Begun J, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Bellarosa C, Belleudi F, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bose S, Botana LM, Botas J, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Bultynck G, Burada F, Burgoyne JR, Bustos V, Butturini E, Byrd A, Cadwell K, Cai J, Cai L, Cai Q, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campello S, Campos JC, Canesi L, Caniggia I, Canonico B, Cao B, Caraglia M, Carchman EH, Cardenas C, Cardoso SM, Carew JS, Carleton G, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carosi JM, Carra S, Carrier L, Carroll B, Carter AB, Carvalho AN, Casas J, Cassioli C, Castillo EF, Castillo-Lluva S, Castori M, Castro-Caldas M, Catz SD, Cavadas C, Cavaliere F, Cavallini G, Cavinato M, Cayuela ML, Cebollada Rica P, Cecarini V, Cechowska-Pasko M, Cenci S, Cervia D, Cetintas VB, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chakrabarti O, Chakraborty T, Chakraborty T, Chamilos G, Chan DW, Chan EYW, Chan ED, Chan HYE, Chan HH, Chan H, Chan MTV, Chan YS, Chandra PK, Chang CP, Chang C, Chang HC, Chang K, Chao J, Chapman T, Chatterjee S, Chaube SK, Chaudhary A, Chauhan S, Chaum E, Cheetham ME, Chen CS, Chen GC, Chen JF, Chen LL, Chen L, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1. Autophagy. 2021 Jan; 17(1):1-382. PMID: 33634751; PMCID: PMC7996087.
      Citations: 357     Fields:    Translation:HumansAnimalsCells
    64. Koppula P, Zhuang L, Gan B. Cytochrome P450 reductase (POR) as a ferroptosis fuel. Protein Cell. 2021 09; 12(9):675-679. PMID: 33539003; PMCID: PMC8403093.
      Citations: 5     Fields:    Translation:HumansCells
    65. Song S, Chen Q, Li Y, Lei G, Scott A, Huo L, Li CY, Estrella JS, Correa A, Pizzi MP, Ma L, Jin J, Liu B, Wang Y, Xiao L, Hofstetter WL, Lee JH, Weston B, Bhutani M, Shanbhag N, Johnson RL, Gan B, Wei S, Ajani JA. Targeting cancer stem cells with a pan-BCL-2 inhibitor in preclinical and clinical settings in patients with gastroesophageal carcinoma. Gut. 2021 12; 70(12):2238-2248. PMID: 33487592; PMCID: PMC9720890.
      Citations: 2     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    66. Shen X, Wang R, Kim MJ, Hu Q, Hsu CC, Yao J, Klages-Mundt N, Tian Y, Lynn E, Brewer TF, Zhang Y, Arun B, Gan B, Andreeff M, Takeda S, Chen J, Park JI, Shi X, Chang CJ, Jung SY, Qin J, Li L. A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia. Mol Cell. 2020 12 17; 80(6):1013-1024.e6. PMID: 33338401; PMCID: PMC8600940.
      Citations: 9     Fields:    Translation:HumansCells
    67. Liu X, Zhang Y, Zhuang L, Olszewski K, Gan B. NADPH debt drives redox bankruptcy: SLC7A11/xCT-mediated cystine uptake as a double-edged sword in cellular redox regulation. Genes Dis. 2021 Nov; 8(6):731-745. PMID: 34522704; PMCID: PMC8427322.
      Citations: 8     
    68. Koppula P, Zhuang L, Gan B. Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy. Protein Cell. 2021 08; 12(8):599-620. PMID: 33000412; PMCID: PMC8310547.
      Citations: 133     Fields:    Translation:HumansCells
    69. Lee H, Zhuang L, Gan B. Energy stress inhibits ferroptosis via AMPK. Mol Cell Oncol. 2020; 7(4):1761242. PMID: 32944623; PMCID: PMC7469505.
      Citations: 8     
    70. Zhang Y, Shi J, Liu X, Xiao Z, Lei G, Lee H, Koppula P, Cheng W, Mao C, Zhuang L, Ma L, Li W, Gan B. H2A Monoubiquitination Links Glucose Availability to Epigenetic Regulation of the Endoplasmic Reticulum Stress Response and Cancer Cell Death. Cancer Res. 2020 06 01; 80(11):2243-2256. PMID: 32273282; PMCID: PMC7272265.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    71. Liu X, Olszewski K, Zhang Y, Lim EW, Shi J, Zhang X, Zhang J, Lee H, Koppula P, Lei G, Zhuang L, You MJ, Fang B, Li W, Metallo CM, Poyurovsky MV, Gan B. Cystine transporter regulation of pentose phosphate pathway dependency and disulfide stress exposes a targetable metabolic vulnerability in cancer. Nat Cell Biol. 2020 04; 22(4):476-486. PMID: 32231310; PMCID: PMC7194135.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    72. Chauhan AS, Zhuang L, Gan B. Spatial control of AMPK signaling at subcellular compartments. Crit Rev Biochem Mol Biol. 2020 02; 55(1):17-32. PMID: 32069425; PMCID: PMC8237692.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    73. Lee H, Zandkarimi F, Zhang Y, Meena JK, Kim J, Zhuang L, Tyagi S, Ma L, Westbrook TF, Steinberg GR, Nakada D, Stockwell BR, Gan B. Energy-stress-mediated AMPK activation inhibits ferroptosis. Nat Cell Biol. 2020 02; 22(2):225-234. PMID: 32029897; PMCID: PMC7008777.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    74. Lei G, Zhang Y, Koppula P, Liu X, Zhang J, Lin SH, Ajani JA, Xiao Q, Liao Z, Wang H, Gan B. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Res. 2020 02; 30(2):146-162. PMID: 31949285; PMCID: PMC7015061.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    75. Chauhan AS, Zhuang L, Gan B. Antagonism between Antiviral Signaling and Glycolysis. Trends Endocrinol Metab. 2019 09; 30(9):571-573. PMID: 31349923; PMCID: PMC7944876.
      Citations: 5     Fields:    Translation:Cells
    76. Gan B. DUBbing Ferroptosis in Cancer Cells. Cancer Res. 2019 04 15; 79(8):1749-1750. PMID: 30987975; PMCID: PMC7193871.
      Citations: 12     Fields:    Translation:HumansCells
    77. Zhang Y, Koppula P, Gan B. Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle. 2019 04; 18(8):773-783. PMID: 30907299; PMCID: PMC6527290.
      Citations: 35     Fields:    Translation:HumansCells
    78. Zhang Y, Zhuang L, Gan B. BAP1 suppresses tumor development by inducing ferroptosis upon SLC7A11 repression. Mol Cell Oncol. 2019; 6(1):1536845. PMID: 30788415; PMCID: PMC6370386.
      Citations: 28     
    79. Kim J, Piao HL, Kim BJ, Yao F, Han Z, Wang Y, Xiao Z, Siverly AN, Lawhon SE, Ton BN, Lee H, Zhou Z, Gan B, Nakagawa S, Ellis MJ, Liang H, Hung MC, You MJ, Sun Y, Ma L. Long noncoding RNA MALAT1 suppresses breast cancer metastasis. Nat Genet. 2018 12; 50(12):1705-1715. PMID: 30349115; PMCID: PMC6265076.
      Citations: 249     Fields:    Translation:HumansAnimalsCells
    80. Chauhan AS, Liu X, Jing J, Lee H, Yadav RK, Liu J, Zhou Y, Gan B. STIM2 interacts with AMPK and regulates calcium-induced AMPK activation. FASEB J. 2019 02; 33(2):2957-2970. PMID: 30335546; PMCID: PMC6338636.
      Citations: 17     Fields:    Translation:HumansCells
    81. Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, Huang P, Li W, Gan B. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018 10; 20(10):1181-1192. PMID: 30202049; PMCID: PMC6170713.
      Citations: 208     Fields:    Translation:HumansAnimalsCells
    82. Koppula P, Zhang Y, Zhuang L, Gan B. Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer. Cancer Commun (Lond). 2018 04 25; 38(1):12. PMID: 29764521; PMCID: PMC5993148.
      Citations: 131     Fields:    Translation:HumansCells
    83. Yadav RK, Chauhan AS, Zhuang L, Gan B. FoxO transcription factors in cancer metabolism. Semin Cancer Biol. 2018 06; 50:65-76. PMID: 29309929; PMCID: PMC5986595.
      Citations: 40     Fields:    Translation:Humans
    84. Xiao ZD, Han L, Lee H, Zhuang L, Zhang Y, Baddour J, Nagrath D, Wood CG, Gu J, Wu X, Liang H, Gan B. Energy stress-induced lncRNA FILNC1 represses c-Myc-mediated energy metabolism and inhibits renal tumor development. Nat Commun. 2017 10 04; 8(1):783. PMID: 28978906; PMCID: PMC5627275.
      Citations: 94     Fields:    Translation:HumansCells
    85. Koppula P, Zhang Y, Shi J, Li W, Gan B. The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate. J Biol Chem. 2017 08 25; 292(34):14240-14249. PMID: 28630042; PMCID: PMC5572906.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    86. Jonasch E, Hasanov E, Corn PG, Moss T, Shaw KR, Stovall S, Marcott V, Gan B, Bird S, Wang X, Do KA, Altamirano PF, Zurita AJ, Doyle LA, Lara PN, Tannir NM. A randomized phase 2 study of MK-2206 versus everolimus in refractory renal cell carcinoma. Ann Oncol. 2017 04 01; 28(4):804-808. PMID: 28049139; PMCID: PMC5834088.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    87. Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3192-3197. PMID: 28275095; PMCID: PMC5373337.
      Citations: 42     Fields:    Translation:AnimalsCells
    88. Liu X, Gan B. lncRNA NBR2 modulates cancer cell sensitivity to phenformin through GLUT1. Cell Cycle. 2016 Dec 16; 15(24):3471-3481. PMID: 27792451; PMCID: PMC5224451.
      Citations: 41     Fields:    Translation:HumansCells
    89. Kim J, Siverly AN, Chen D, Wang M, Yuan Y, Wang Y, Lee H, Zhang J, Muller WJ, Liang H, Gan B, Yang X, Sun Y, You MJ, Ma L. Ablation of miR-10b Suppresses Oncogene-Induced Mammary Tumorigenesis and Metastasis and Reactivates Tumor-Suppressive Pathways. Cancer Res. 2016 11 01; 76(21):6424-6435. PMID: 27569213; PMCID: PMC5093036.
      Citations: 37     Fields:    Translation:AnimalsCells
    90. Xiao ZD, Zhuang L, Gan B. Long non-coding RNAs in cancer metabolism. Bioessays. 2016 10; 38(10):991-6. PMID: 27550823; PMCID: PMC5144540.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    91. Xiao ZD, Liu X, Zhuang L, Gan B. NBR2: A former junk gene emerges as a key player in tumor suppression. Mol Cell Oncol. 2016 Jul; 3(4):e1187322. PMID: 27652330; PMCID: PMC4972102.
      Citations: 13     
    92. Liu X, Xiao ZD, Gan B. An lncRNA switch for AMPK activation. Cell Cycle. 2016 08 02; 15(15):1948-9. PMID: 27152502; PMCID: PMC4968966.
      Citations: 14     Fields:    Translation:Cells
    93. Lee H, Dai F, Zhuang L, Xiao ZD, Kim J, Zhang Y, Ma L, You MJ, Wang Z, Gan B. BAF180 regulates cellular senescence and hematopoietic stem cell homeostasis through p21. Oncotarget. 2016 Apr 12; 7(15):19134-46. PMID: 26992241; PMCID: PMC4991371.
      Citations: 29     Fields:    Translation:AnimalsCells
    94. Liu X, Xiao ZD, Han L, Zhang J, Lee SW, Wang W, Lee H, Zhuang L, Chen J, Lin HK, Wang J, Liang H, Gan B. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nat Cell Biol. 2016 Apr; 18(4):431-42. PMID: 26999735; PMCID: PMC4814347.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    95. Wang W, Xiao ZD, Li X, Aziz KE, Gan B, Johnson RL, Chen J. AMPK modulates Hippo pathway activity to regulate energy homeostasis. Nat Cell Biol. 2015 Apr; 17(4):490-9. PMID: 25751139; PMCID: PMC4380807.
      Citations: 222     Fields:    Translation:HumansAnimalsCells
    96. Lin A, Piao HL, Zhuang L, Sarbassov dos D, Ma L, Gan B. FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway. Cancer Res. 2014 Mar 15; 74(6):1682-93. PMID: 24448243; PMCID: PMC4087030.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    97. Hu J, Ho AL, Yuan L, Hu B, Hua S, Hwang SS, Zhang J, Hu T, Zheng H, Gan B, Wu G, Wang YA, Chin L, DePinho RA. From the Cover: Neutralization of terminal differentiation in gliomagenesis. Proc Natl Acad Sci U S A. 2013 Sep 03; 110(36):14520-7. PMID: 23918370; PMCID: PMC3767545.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    98. Lin A, Yao J, Zhuang L, Wang D, Han J, Lam EW, TCGA Research Network, Gan B. The FoxO-BNIP3 axis exerts a unique regulation of mTORC1 and cell survival under energy stress. Oncogene. 2014 Jun 12; 33(24):3183-94. PMID: 23851496; PMCID: PMC4365448.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    99. Keniry M, Pires MM, Mense S, Lefebvre C, Gan B, Justiano K, Lau YK, Hopkins B, Hodakoski C, Koujak S, Toole J, Fenton F, Calahan A, Califano A, DePinho RA, Maurer M, Parsons R. Survival factor NFIL3 restricts FOXO-induced gene expression in cancer. Genes Dev. 2013 Apr 15; 27(8):916-27. PMID: 23630076; PMCID: PMC3650228.
      Citations: 25     Fields:    Translation:HumansCells
    100. Rosborough BR, Matta BM, Lee K, Gan B, DePinho RA, Hackstein H, Boothby M, Turnquist HR, Thomson AW, Ra?ch-Regu? D. Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction. Blood. 2013 May 02; 121(18):3619-30. PMID: 23444404; PMCID: PMC3643762.
      Citations: 30     Fields:    Translation:AnimalsCells
    101. Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA. Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell. 2012 Apr 27; 149(3):656-70. PMID: 22541435; PMCID: PMC3472002.
      Citations: 843     Fields:    Translation:HumansAnimalsCells
    102. Hu J, Hwang SS, Liesa M, Gan B, Sahin E, Jaskelioff M, Ding Z, Ying H, Boutin AT, Zhang H, Johnson S, Ivanova E, Kost-Alimova M, Protopopov A, Wang YA, Shirihai OS, Chin L, DePinho RA. Antitelomerase therapy provokes ALT and mitochondrial adaptive mechanisms in cancer. Cell. 2012 Feb 17; 148(4):651-63. PMID: 22341440; PMCID: PMC3286017.
      Citations: 143     Fields:    Translation:HumansAnimalsCells
    103. Ding Z, Wu CJ, Jaskelioff M, Ivanova E, Kost-Alimova M, Protopopov A, Chu GC, Wang G, Lu X, Labrot ES, Hu J, Wang W, Xiao Y, Zhang H, Zhang J, Zhang J, Gan B, Perry SR, Jiang S, Li L, Horner JW, Wang YA, Chin L, DePinho RA. Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases. Cell. 2012 Mar 02; 148(5):896-907. PMID: 22341455; PMCID: PMC3629723.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    104. Zhang K, Li L, Qi Y, Zhu X, Gan B, DePinho RA, Averitt T, Guo S. Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice. Endocrinology. 2012 Feb; 153(2):631-46. PMID: 22147007; PMCID: PMC5393302.
      Citations: 73     Fields:    Translation:AnimalsCells
    105. Zhang Y, Gan B, Liu D, Paik JH. FoxO family members in cancer. Cancer Biol Ther. 2011 Aug 15; 12(4):253-9. PMID: 21613825.
      Citations: 87     Fields:    Translation:HumansCells
    106. Wei H, Wei S, Gan B, Peng X, Zou W, Guan JL. Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis. Genes Dev. 2011 Jul 15; 25(14):1510-27. PMID: 21764854; PMCID: PMC3143941.
      Citations: 203     Fields:    Translation:AnimalsCells
    107. Gan B, Hu J, Jiang S, Liu Y, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L, Depinho RA, Sahin E. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature. 2010 Dec 02; 468(7324):701-4. PMID: 21124456; PMCID: PMC3058342.
      Citations: 227     Fields:    Translation:AnimalsCells
    108. Gan B, Lim C, Chu G, Hua S, Ding Z, Collins M, Hu J, Jiang S, Fletcher-Sananikone E, Zhuang L, Chang M, Zheng H, Wang YA, Kwiatkowski DJ, Kaelin WG, Signoretti S, DePinho RA. FoxOs enforce a progression checkpoint to constrain mTORC1-activated renal tumorigenesis. Cancer Cell. 2010 Nov 16; 18(5):472-84. PMID: 21075312; PMCID: PMC3023886.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    109. Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, Brennan C, Wang YA, Hahn WC, Chin L, DePinho RA. PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas. Cancer Cell. 2010 May 18; 17(5):497-509. PMID: 20478531; PMCID: PMC2900858.
      Citations: 138     Fields:    Translation:HumansAnimalsCells
    110. Liang CC, Wang C, Peng X, Gan B, Guan JL. Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration. J Biol Chem. 2010 Jan 29; 285(5):3499-509. PMID: 19940130; PMCID: PMC2823459.
      Citations: 112     Fields:    Translation:AnimalsCells
    111. Gan B, DePinho RA. mTORC1 signaling governs hematopoietic stem cell quiescence. Cell Cycle. 2009 Apr 01; 8(7):1003-6. PMID: 19270523; PMCID: PMC2743144.
      Citations: 60     Fields:    Translation:AnimalsCells
    112. Wei H, Gan B, Wu X, Guan JL. Inactivation of FIP200 leads to inflammatory skin disorder, but not tumorigenesis, in conditional knock-out mouse models. J Biol Chem. 2009 Feb 27; 284(9):6004-13. PMID: 19106106; PMCID: PMC2645843.
      Citations: 25     Fields:    Translation:AnimalsCells
    113. Gan B, Jiang S, Sanchez-Aguilera A, Scott KL, Chin L, Williams DA, Kwiatkowski DJ, DePinho RA, Sahin E. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proc Natl Acad Sci U S A. 2008 Dec 09; 105(49):19384-9. PMID: 19052232; PMCID: PMC2593615.
      Citations: 123     Fields:    Translation:AnimalsCells
    114. Martin N, Schwamborn K, Urlaub H, Gan B, Guan JL, Dejean A. Spatial interplay between PIASy and FIP200 in the regulation of signal transduction and transcriptional activity. Mol Cell Biol. 2008 Apr; 28(8):2771-81. PMID: 18285457; PMCID: PMC2293096.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    115. Gan B, Guan JL. FIP200, a key signaling node to coordinately regulate various cellular processes. Cell Signal. 2008 May; 20(5):787-94. PMID: 18036779; PMCID: PMC2278039.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    116. Nagy T, Wei H, Shen TL, Peng X, Liang CC, Gan B, Guan JL. Mammary epithelial-specific deletion of the focal adhesion kinase gene leads to severe lobulo-alveolar hypoplasia and secretory immaturity of the murine mammary gland. J Biol Chem. 2007 Oct 26; 282(43):31766-76. PMID: 17716968.
      Citations: 39     Fields:    Translation:AnimalsCells
    117. Gan B, Yoo Y, Guan JL. Association of focal adhesion kinase with tuberous sclerosis complex 2 in the regulation of s6 kinase activation and cell growth. J Biol Chem. 2006 Dec 08; 281(49):37321-9. PMID: 17043358.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    118. Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL. Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways. J Cell Biol. 2006 Oct 09; 175(1):121-33. PMID: 17015619; PMCID: PMC2064504.
      Citations: 114     Fields:    Translation:AnimalsCells
    119. Wei H, Wang X, Gan B, Urvalek AM, Melkoumian ZK, Guan JL, Zhao J. Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulation. J Biol Chem. 2006 Jun 16; 281(24):16664-71. PMID: 16617055.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    120. Wu X, Gan B, Yoo Y, Guan JL. FAK-mediated src phosphorylation of endophilin A2 inhibits endocytosis of MT1-MMP and promotes ECM degradation. Dev Cell. 2005 Aug; 9(2):185-96. PMID: 16054026.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    121. Melkoumian ZK, Peng X, Gan B, Wu X, Guan JL. Mechanism of cell cycle regulation by FIP200 in human breast cancer cells. Cancer Res. 2005 Aug 01; 65(15):6676-84. PMID: 16061648.
      Citations: 38     Fields:    Translation:HumansCells
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