| Item Type | Name |
|
Academic Article
|
Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.
|
|
Academic Article
|
Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action.
|
|
Academic Article
|
SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells.
|
|
Academic Article
|
Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members.
|
|
Academic Article
|
Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary.
|
|
Academic Article
|
Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1.
|
|
Academic Article
|
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification.
|
|
Academic Article
|
Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation.
|
|
Academic Article
|
Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction.
|
|
Academic Article
|
Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.
|
|
Academic Article
|
The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors.
|
|
Academic Article
|
Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor.
|
|
Academic Article
|
Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone.
|
|
Academic Article
|
Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.
|
|
Academic Article
|
Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice.
|
|
Academic Article
|
Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone.
|
|
Academic Article
|
SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
|
|
Academic Article
|
Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover.
|
|
Academic Article
|
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice.
|
|
Academic Article
|
Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family.
|
|
Academic Article
|
Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways.
|
|
Academic Article
|
Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1).
|
|
Academic Article
|
Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD.
|
|
Academic Article
|
The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome.
|
|
Academic Article
|
Results of a search for the mechanisms of steroid receptor regulation of gene expression.
|
|
Academic Article
|
SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.
|
|
Academic Article
|
Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly.
|
|
Academic Article
|
Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone.
|
|
Academic Article
|
Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function.
|
|
Academic Article
|
Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice.
|
|
Academic Article
|
The expanding cosmos of nuclear receptor coactivators.
|
|
Academic Article
|
SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock.
|
|
Academic Article
|
Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation.
|
|
Academic Article
|
An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response.
|
|
Academic Article
|
The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression.
|
|
Academic Article
|
SRC-3 transcription-coupled activation, degradation, and the ubiquitin clock: is there enough coactivator to go around in cells?
|
|
Academic Article
|
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.
|
|
Academic Article
|
Cracking the coregulator codes.
|
|
Academic Article
|
Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1.
|
|
Academic Article
|
The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
|
|
Academic Article
|
Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation.
|
|
Academic Article
|
Streamlined analysis schema for high-throughput identification of endogenous protein complexes.
|
|
Academic Article
|
Nuclear receptor coactivators: structural and functional biochemistry.
|
|
Academic Article
|
Minireview: nuclear receptor and coregulator proteomics--2012 and beyond.
|
|
Academic Article
|
Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction.
|
|
Academic Article
|
Steroid receptor coactivator-1 is not required for androgen-mediated sexual differentiation of spinal motoneurons.
|
|
Academic Article
|
Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription?
|
|
Academic Article
|
Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins.
|
|
Academic Article
|
AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice.
|
|
Academic Article
|
Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator.
|
|
Academic Article
|
Transcriptional regulation by steroid receptor coactivator phosphorylation.
|
|
Academic Article
|
Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice.
|
|
Academic Article
|
Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice.
|
|
Academic Article
|
Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor.
|
|
Academic Article
|
The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.
|
|
Academic Article
|
Absence of the steroid receptor coactivator-3 induces B-cell lymphoma.
|
|
Academic Article
|
Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3.
|
|
Academic Article
|
Molecular biology. Little molecules with big goals.
|
|
Academic Article
|
Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program.
|
|
Academic Article
|
Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway.
|
|
Academic Article
|
The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}.
|
|
Academic Article
|
Biochemical control of CARM1 enzymatic activity by phosphorylation.
|
|
Academic Article
|
Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.
|
|
Concept
|
Histone Code
|
|
Concept
|
Histone Acetyltransferases
|
|
Concept
|
Histone Deacetylase 1
|
|
Concept
|
Sin3 Histone Deacetylase and Corepressor Complex
|
|
Concept
|
Histone Deacetylases
|
|
Concept
|
Histone Deacetylase 2
|
|
Concept
|
Histones
|
|
Concept
|
Histone-Lysine N-Methyltransferase
|
|
Academic Article
|
An epigenomic approach to therapy for tamoxifen-resistant breast cancer.
|
|
Academic Article
|
Structure of a biologically active estrogen receptor-coactivator complex on DNA.
|
|
Academic Article
|
miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation.
|
|
Academic Article
|
Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk.
|
|
Academic Article
|
Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency.
|
|
Academic Article
|
Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation.
|
|
Academic Article
|
Histone Marks in the 'Driver's Seat': Functional Roles in Steering the Transcription Cycle.
|
|
Academic Article
|
Structural and Functional Impacts of ER Coactivator Sequential Recruitment.
|
|
Academic Article
|
Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma.
|