rho Guanine Nucleotide Dissociation Inhibitor alpha
"rho Guanine Nucleotide Dissociation Inhibitor alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundantly-expressed rho GDP-dissociation inhibitor subtype that regulates a broad variety of RHO GTPASES.
| Descriptor ID |
D062948
|
| MeSH Number(s) |
D12.644.360.325.225.500.100 D12.776.476.325.225.500.100
|
| Concept/Terms |
rho Guanine Nucleotide Dissociation Inhibitor alpha- rho Guanine Nucleotide Dissociation Inhibitor alpha
- rho GDP-Dissociation Inhibitor 1
- rho GDP Dissociation Inhibitor 1
- rhoGDIalpha
- rho Guanine Nucleotide Dissociation Inhibitor 1
- rhoGDI1
- rho GDP Dissociation Inhibitor (GDI) alpha
- rho GDIalpha
|
Below are MeSH descriptors whose meaning is more general than "rho Guanine Nucleotide Dissociation Inhibitor alpha".
Below are MeSH descriptors whose meaning is more specific than "rho Guanine Nucleotide Dissociation Inhibitor alpha".
This graph shows the total number of publications written about "rho Guanine Nucleotide Dissociation Inhibitor alpha" by people in this website by year, and whether "rho Guanine Nucleotide Dissociation Inhibitor alpha" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "rho Guanine Nucleotide Dissociation Inhibitor alpha" by people in Profiles.
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Rho GDP-dissociation inhibitor a is a potential prognostic biomarker and controls telomere regulation in colorectal cancer. Cancer Sci. 2017 Jul; 108(7):1293-1302.
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Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERa-positive breast cancer. Breast Cancer Res Treat. 2015 Nov; 154(2):225-37.
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Protein tyrosine phosphatase-PEST and ?8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells. Mol Cell Biol. 2015 Apr; 35(8):1401-13.
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14-3-3t promotes breast cancer invasion and metastasis by inhibiting RhoGDIa. Mol Cell Biol. 2014 Jul; 34(14):2635-49.
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av?8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion. Mol Biol Cell. 2013 Feb; 24(4):474-82.
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Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a. J Natl Cancer Inst. 2011 Apr 06; 103(7):538-52.
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Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J. 2004 May; 18(7):857-9.
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Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Development. 2002 Apr; 129(7):1705-14.