Receptors, Purinergic P2Y12
"Receptors, Purinergic P2Y12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of purinergic P2Y receptors that have a preference for ADP binding and are coupled to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI. The P2Y12 purinergic receptors are found in PLATELETS where they play an important role regulating PLATELET ACTIVATION.
| Descriptor ID |
D058925
|
| MeSH Number(s) |
D12.776.543.750.695.700.720.500.300 D12.776.543.750.720.700.720.750.300
|
| Concept/Terms |
Receptors, Purinergic P2Y12- Receptors, Purinergic P2Y12
- P2Y12 Receptors, Purinergic
- Purinergic P2Y12 Receptors
- Purinergic Receptor P2Y, G-Protein Coupled, 12
- Purinoceptor P2Y12
- P2Y12, Purinoceptor
- P2Y12 Purinoceptors
- Purinoceptors, P2Y12
- P2Y(ADP) Receptor
- P2Y(T) Receptor
- P2Y12 Purinoceptor
- Purinoceptor, P2Y12
- Purinoceptor P2T
- P2T, Purinoceptor
- Purinergic Receptor P2Y12
- P2Y12, Purinergic Receptor
- P2T Purinoceptor
- Purinoceptor, P2T
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2Y12".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.695.700.720.500]
- Receptors, Purinergic P2Y12 [D12.776.543.750.695.700.720.500.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.720.700.720.750]
- Receptors, Purinergic P2Y12 [D12.776.543.750.720.700.720.750.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2Y12".
This graph shows the total number of publications written about "Receptors, Purinergic P2Y12" by people in this website by year, and whether "Receptors, Purinergic P2Y12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Receptors, Purinergic P2Y12" by people in Profiles.
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Aspirin vs P2Y12 Inhibitors: A Few Questions Unanswered. J Am Coll Cardiol. 2024 01 02; 83(1):e7.
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Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome. J Neurosci. 2020 02 12; 40(7):1453-1482.
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Role of ADP receptors on platelets in the growth of ovarian cancer. Blood. 2017 09 07; 130(10):1235-1242.
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Dipstick proteinuria is an independent predictor of high on treatment platelet reactivity in patients on clopidogrel, but not aspirin, admitted for major adverse cardiovascular events. Platelets. 2015; 26(7):651-6.
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Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways. Thromb Haemost. 2013 Dec; 110(6):1223-31.
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Platelet activity measured by a rapid turnaround assay identifies coronary artery bypass grafting patients at increased risk for bleeding and transfusion complications after clopidogrel administration. J Thorac Cardiovasc Surg. 2013 Nov; 146(5):1259-1266, 1266.e1; discussion 1266.
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Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network. Blood. 2013 Mar 07; 121(10):1875-85.
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The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling. J Clin Invest. 2012 Oct; 122(10):3579-92.
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P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease. Int J Lab Hematol. 2012 Oct; 34(5):473-83.
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Augmentation of U46619 induced human platelet aggregation by aspirin. Platelets. 2009 Mar; 20(2):111-9.