Receptors, Purinergic P2Y2
"Receptors, Purinergic P2Y2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of purinergic P2Y receptors that have a preference for ATP and UTP. The activated P2Y2 receptor acts through a G-PROTEIN-coupled PHOSPHATIDYLINOSITOL and intracellular CALCIUM SIGNALING pathway.
| Descriptor ID |
D058473
|
| MeSH Number(s) |
D12.776.543.750.695.700.720.500.200 D12.776.543.750.720.700.720.750.200
|
| Concept/Terms |
Receptors, Purinergic P2Y2- Receptors, Purinergic P2Y2
- P2Y2 Receptors, Purinergic
- Purinergic P2Y2 Receptors
- Purinoreceptor P2U
- P2Y2 Receptors
- Receptors, P2Y2
- Puringergic Receptor P2Y, G-Protein Coupled, 2
- P2Y2 Purinoceptor
- Purinoceptor, P2Y2
- P2U Receptors
- Receptors, P2U
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2Y2".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P2 [D12.776.543.750.695.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.695.700.720.500]
- Receptors, Purinergic P2Y2 [D12.776.543.750.695.700.720.500.200]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2Y [D12.776.543.750.720.700.720.750]
- Receptors, Purinergic P2Y2 [D12.776.543.750.720.700.720.750.200]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2Y2".
This graph shows the total number of publications written about "Receptors, Purinergic P2Y2" by people in this website by year, and whether "Receptors, Purinergic P2Y2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Receptors, Purinergic P2Y2" by people in Profiles.
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Distribution of P2Y and P2X purinergic receptor expression within the intestine. Am J Physiol Gastrointest Liver Physiol. 2024 02 01; 326(2):G107-G119.
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P2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality. Am J Physiol Gastrointest Liver Physiol. 2023 11 01; 325(5):G471-G491.
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Exercise training ameliorates cerebrovascular dysfunction in a murine model of Alzheimer's disease: role of the P2Y2 receptor and endoplasmic reticulum stress. Am J Physiol Heart Circ Physiol. 2020 06 01; 318(6):H1559-H1569.
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P2Y2 purinergic receptor activation is essential for efficient hepatocyte proliferation in response to partial hepatectomy. Am J Physiol Gastrointest Liver Physiol. 2014 Dec 01; 307(11):G1073-87.
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A mutation in TRPC6 channels abolishes their activation by hypoosmotic stretch but does not affect activation by diacylglycerol or G protein signaling cascades. Am J Physiol Renal Physiol. 2014 May 01; 306(9):F1018-25.
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Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages. J Biol Chem. 2006 Nov 17; 281(46):35147-55.
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Extracellular ATP activates c-jun N-terminal kinase signaling and cell cycle progression in hepatocytes. Hepatology. 2004 Feb; 39(2):393-402.
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P2u receptor-mediated release of endothelium-derived relaxing factor/nitric oxide and endothelium-derived hyperpolarizing factor from cerebrovascular endothelium in rats. Stroke. 1999 May; 30(5):1125-33.
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P2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion. Am J Physiol. 1999 01; 276(1):H33-41.
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Endothelial-mediated dilations of rat middle cerebral arteries by ATP and ADP. Am J Physiol. 1997 Sep; 273(3 Pt 2):H1472-7.