"Myofibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spindle-shaped cells with characteristic CONTRACTILE PROTEINS and structures that contribute to the WOUND HEALING process. They occur in GRANULATION TISSUE and also in pathological processes such as FIBROSIS.
| Descriptor ID |
D058628
|
| MeSH Number(s) |
A11.329.228.975 A11.620.520.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Myofibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Myofibroblasts".
This graph shows the total number of publications written about "Myofibroblasts" by people in this website by year, and whether "Myofibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 4 | 4 | 8 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 6 | 7 |
| 2014 | 3 | 4 | 7 |
| 2015 | 1 | 3 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 3 | 2 | 5 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 1 | 2 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Myofibroblasts" by people in Profiles.
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Macrophages in the infarcted heart acquire a fibrogenic phenotype, expressing matricellular proteins, but do not undergo fibroblast conversion. J Mol Cell Cardiol. 2024 Nov; 196:152-167.
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Fibroblast Smad7 Induction Protects the Remodeling Pressure-Overloaded Heart. Circ Res. 2024 Jul 19; 135(3):453-469.
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Milk fat globule-epidermal growth factor 8 (MFGE8) prevents intestinal fibrosis. Gut. 2024 06 06; 73(7):1110-1123.
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The fate and role of the pericytes in myocardial diseases. Eur J Clin Invest. 2024 Aug; 54(8):e14204.
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Fibroblast heterogeneity in pulmonary fibrosis: a new target for therapeutics development? Eur Respir J. 2024 Feb; 63(2).
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Cloning a profibrotic stem cell variant in idiopathic pulmonary fibrosis. Sci Transl Med. 2023 04 26; 15(693):eabp9528.
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Fenbendazole Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Suppression of Fibroblast-to-Myofibroblast Differentiation. Int J Mol Sci. 2022 Nov 15; 23(22).
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Human intestinal myofibroblasts deposited collagen VI enhances adhesiveness for T cells - A novel mechanism for maintenance of intestinal inflammation. Matrix Biol. 2022 11; 113:1-21.
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Properties and Functions of Fibroblasts and Myofibroblasts in Myocardial Infarction. Cells. 2022 04 20; 11(9).
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Smad-dependent pathways in the infarcted and failing heart. Curr Opin Pharmacol. 2022 06; 64:102207.