Cancer-Associated Fibroblasts
"Cancer-Associated Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.
| Descriptor ID |
D000072645
|
| MeSH Number(s) |
A11.329.228.105
|
| Concept/Terms |
Cancer-Associated Fibroblasts- Cancer-Associated Fibroblasts
- Cancer-Associated Fibroblast
- Fibroblast, Cancer-Associated
- Fibroblasts, Cancer-Associated
- Cancer Associated Fibroblasts
- Cancer Associated Fibroblast
- Fibroblast, Cancer Associated
- Fibroblasts, Cancer Associated
- Tumor-Associated Fibroblasts
- Fibroblast, Tumor-Associated
- Fibroblasts, Tumor-Associated
- Tumor Associated Fibroblasts
- Tumor-Associated Fibroblast
|
Below are MeSH descriptors whose meaning is more general than "Cancer-Associated Fibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Cancer-Associated Fibroblasts".
This graph shows the total number of publications written about "Cancer-Associated Fibroblasts" by people in this website by year, and whether "Cancer-Associated Fibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Cancer-Associated Fibroblasts" by people in Profiles.
-
Metastatic medulloblastoma remodels the local leptomeningeal microenvironment to promote further metastatic colonization and growth. Nat Cell Biol. 2025 May; 27(5):863-874.
-
Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
-
Avoiding Extinction: Cancer-Associated Fibroblasts Help Triple-Negative Breast Cancer Outrun Chemotherapy. Cancer Res. 2023 11 15; 83(22):3667-3669.
-
Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts. Cell Rep Med. 2022 06 21; 3(6):100541.
-
ELF3 mediates IL-1a induced differentiation of mesenchymal stem cells to inflammatory iCAFs. Stem Cells. 2021 12; 39(12):1766-1777.
-
Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity. Cell Rep. 2021 04 20; 35(3):109009.
-
Fibroblast heterogeneity and its impact on extracellular matrix and immune landscape remodeling in cancer. Matrix Biol. 2020 09; 91-92:8-18.
-
Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis. Gynecol Oncol. 2019 05; 153(2):405-415.
-
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis. Cell Metab. 2019 01 08; 29(1):141-155.e9.
-
Inflammatory breast cancer biology: the tumour microenvironment is key. Nat Rev Cancer. 2018 08; 18(8):485-499.