Cancer-Associated Fibroblasts
"Cancer-Associated Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.
Descriptor ID |
D000072645
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MeSH Number(s) |
A11.329.228.105
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Concept/Terms |
Cancer-Associated Fibroblasts- Cancer-Associated Fibroblasts
- Cancer-Associated Fibroblast
- Fibroblast, Cancer-Associated
- Fibroblasts, Cancer-Associated
- Cancer Associated Fibroblasts
- Cancer Associated Fibroblast
- Fibroblast, Cancer Associated
- Fibroblasts, Cancer Associated
- Tumor-Associated Fibroblasts
- Fibroblast, Tumor-Associated
- Fibroblasts, Tumor-Associated
- Tumor Associated Fibroblasts
- Tumor-Associated Fibroblast
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Below are MeSH descriptors whose meaning is more general than "Cancer-Associated Fibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Cancer-Associated Fibroblasts".
This graph shows the total number of publications written about "Cancer-Associated Fibroblasts" by people in this website by year, and whether "Cancer-Associated Fibroblasts" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2016 | 1 | 2 | 3 |
2017 | 4 | 2 | 6 |
2018 | 5 | 2 | 7 |
2019 | 4 | 2 | 6 |
2020 | 5 | 2 | 7 |
2021 | 7 | 2 | 9 |
2022 | 5 | 0 | 5 |
2023 | 5 | 0 | 5 |
2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cancer-Associated Fibroblasts" by people in Profiles.
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Cancer-associated fibroblast-secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas. J Clin Invest. 2024 Feb 15; 134(4).
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Cell membrane-anchored and tumor-targeted IL-12 T-cell therapy destroys cancer-associated fibroblasts and disrupts extracellular matrix in heterogenous osteosarcoma xenograft models. J Immunother Cancer. 2024 01 09; 12(1).
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Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression. Cancer Discov. 2023 12 12; 13(12):2652-2673.
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Avoiding Extinction: Cancer-Associated Fibroblasts Help Triple-Negative Breast Cancer Outrun Chemotherapy. Cancer Res. 2023 11 15; 83(22):3667-3669.
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The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer-associated fibroblast subtypes. J Pathol. 2024 Jan; 262(1):22-36.
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Evolution of immune and stromal cell states and ecotypes during gastric adenocarcinoma progression. Cancer Cell. 2023 08 14; 41(8):1407-1426.e9.
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Turning Down Oxygen to Turn Up Inflammation in CAFs. Cancer Res. 2023 05 15; 83(10):1560-1562.
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Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment. Nat Commun. 2022 Nov 04; 13(1):6619.
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Phosphodiesterase type 5 inhibitors enhance chemotherapy in preclinical models of esophageal adenocarcinoma by targeting cancer-associated fibroblasts. Cell Rep Med. 2022 06 21; 3(6):100541.
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Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discov. 2022 06 02; 12(6):1580-1597.