Cancer-Associated Fibroblasts
"Cancer-Associated Fibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Subpopulation of heterogeneous fibroblasts within the TUMOR MICROENVIRONMENT that support NEOPLASTIC CELL TRANSFORMATION and NEOPLASTIC PROCESSES.
| Descriptor ID |
D000072645
|
| MeSH Number(s) |
A11.329.228.105
|
| Concept/Terms |
Cancer-Associated Fibroblasts- Cancer-Associated Fibroblasts
- Cancer-Associated Fibroblast
- Fibroblast, Cancer-Associated
- Fibroblasts, Cancer-Associated
- Cancer Associated Fibroblasts
- Cancer Associated Fibroblast
- Fibroblast, Cancer Associated
- Fibroblasts, Cancer Associated
- Tumor-Associated Fibroblasts
- Fibroblast, Tumor-Associated
- Fibroblasts, Tumor-Associated
- Tumor Associated Fibroblasts
- Tumor-Associated Fibroblast
|
Below are MeSH descriptors whose meaning is more general than "Cancer-Associated Fibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Cancer-Associated Fibroblasts".
This graph shows the total number of publications written about "Cancer-Associated Fibroblasts" by people in this website by year, and whether "Cancer-Associated Fibroblasts" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cancer-Associated Fibroblasts" by people in Profiles.
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Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts. Cell Commun Signal. 2024 Nov 14; 22(1):545.
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CD64+ fibroblast-targeted vilanterol and a STING agonist augment CLDN18.2 BiTEs efficacy against pancreatic cancer by reducing desmoplasia and enriching stem-like CD8+ T cells. Gut. 2024 Nov 11; 73(12):1984-1998.
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Pancreatic Cancer-Associated Fibroblasts: Where Do We Go from Here? Cancer Res. 2024 Nov 04; 84(21):3505-3508.
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Pancreatic stellate cells and the interleukin family: Linking fibrosis and immunity to pancreatic ductal adenocarcinoma (Review). Mol Med Rep. 2024 09; 30(3).
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TSG-6+ cancer-associated fibroblasts modulate myeloid cell responses and impair anti-tumor response to immune checkpoint therapy in pancreatic cancer. Nat Commun. 2024 Jul 10; 15(1):5291.
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The role of the fibroblast in Barrett's esophagus and esophageal adenocarcinoma. Curr Opin Gastroenterol. 2024 Jul 01; 40(4):319-327.
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Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas. Nat Commun. 2024 Mar 20; 15(1):2498.
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Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2-SP1-SAT1 axis. Nat Cell Biol. 2024 Apr; 26(4):613-627.
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Cancer-associated fibroblast-secreted collagen is associated with immune inhibitor receptor LAIR1 in gliomas. J Clin Invest. 2024 Feb 15; 134(4).
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Cell membrane-anchored and tumor-targeted IL-12 T-cell therapy destroys cancer-associated fibroblasts and disrupts extracellular matrix in heterogenous osteosarcoma xenograft models. J Immunother Cancer. 2024 01 09; 12(1).