Baculoviral IAP Repeat-Containing 3 Protein
"Baculoviral IAP Repeat-Containing 3 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A regulator of APOPTOSIS that functions as an E3 ubiquitin protein ligase. It contains three baculoviral IAP repeats in its N-terminal half, a CARD DOMAIN, and a RING finger domain at its C-terminus. It is highly expressed in fetal lung and kidney, and adult lymphoid tissues such as spleen, thymus, and peripheral blood lymphocytes. It functions in INFLAMMATION signaling, the INNATE IMMUNE RESPONSE, cell growth and proliferation, and metastasis of tumor cells.
| Descriptor ID |
D000075747
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| MeSH Number(s) |
D08.811.464.938.750.210.250 D12.644.360.075.437.250 D12.776.476.075.437.250
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| Concept/Terms |
Baculoviral IAP Repeat-Containing 3 Protein- Baculoviral IAP Repeat-Containing 3 Protein
- Baculoviral IAP Repeat Containing 3 Protein
- Apoptosis Inhibitor 2
- Inhibitor 2, Apoptosis
- Inhibitor of Apoptosis Protein 1
- cIAP2 Protein
- c-IAP2 Protein
- Cellular Inhibitor of Apoptosis-2
- Apoptosis-2 Cellular Inhibitor
- Cellular Inhibitor of Apoptosis 2
- Baculoviral IAP Repeat Containing Protein 3
- Inhibitor of Apoptosis 1 Protein
- IAP1 Protein
- BIRC3 Protein
- Hiap-1 Protein
- Hiap 1 Protein
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Below are MeSH descriptors whose meaning is more general than "Baculoviral IAP Repeat-Containing 3 Protein".
Below are MeSH descriptors whose meaning is more specific than "Baculoviral IAP Repeat-Containing 3 Protein".
This graph shows the total number of publications written about "Baculoviral IAP Repeat-Containing 3 Protein" by people in this website by year, and whether "Baculoviral IAP Repeat-Containing 3 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Baculoviral IAP Repeat-Containing 3 Protein" by people in Profiles.
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Recurring Amplification at 11q22.1-q22.2 Locus Plays an Important Role in Lymph Node Metastasis and Radioresistance in OSCC. Sci Rep. 2017 11 22; 7(1):16051.
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Analysis of the inhibitors of apoptosis identifies BIRC3 as a facilitator of malignant progression in glioma. Oncotarget. 2017 Feb 21; 8(8):12695-12704.
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Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10. Cancer Res. 2015 Apr 15; 75(8):1668-74.
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Critical tumor suppressor function mediated by epithelial Mig-6 in endometrial cancer. Cancer Res. 2013 Aug 15; 73(16):5090-9.
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Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases. Mol Cancer Ther. 2011 Apr; 10(4):658-69.
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Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-?B-inducing kinase while activating both canonical and alternative nuclear factor-?B pathways. Blood. 2011 Jan 06; 117(1):200-10.
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NFkappaB activity and transcriptional responses in human breast adenocarcinoma cells after single and fractionated irradiation. Cancer Biol Ther. 2009 May; 8(9):765-73.
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MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression. Cancer Res. 2009 Mar 15; 69(6):2559-67.
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Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol Cell Biol. 2008 Mar; 28(6):2011-22.
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Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. Cancer Cell. 2007 Aug; 12(2):115-30.