"Deoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
| Descriptor ID |
D003840
|
| MeSH Number(s) |
D04.210.500.105.225.272 D04.210.500.221.430.342
|
| Concept/Terms |
Deoxycholic Acid- Deoxycholic Acid
- Acid, Deoxycholic
- Desoxycholic Acid
- Acid, Desoxycholic
- Dihydroxycholanoic Acid
- Acid, Dihydroxycholanoic
|
Below are MeSH descriptors whose meaning is more general than "Deoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Deoxycholic Acid".
This graph shows the total number of publications written about "Deoxycholic Acid" by people in this website by year, and whether "Deoxycholic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxycholic Acid" by people in Profiles.
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Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis. 2014 Jun; 46(6):527-34.
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Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3):G559-66.
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Pharmacodynamic activity of amphotericin B deoxycholate is associated with peak plasma concentrations in a neutropenic murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2006 Feb; 50(2):469-73.
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Bile acids induce MUC2 overexpression in human colon carcinoma cells. Cancer. 2005 Apr 15; 103(8):1606-14.
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Decreased toxicity of liposomal amphotericin B due to association of amphotericin B with high-density lipoproteins: role of lipid transfer protein. J Pharm Sci. 1994 Jul; 83(7):1006-10.
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Disposition and toxicity of amphotericin-B in the hyperlipidemic Zucker rat model. Int J Obes. 1990 Jun; 14(6):465-72.
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Hormonal regulation of phosphatidylinositol breakdown. Life Sci. 1983 May 02; 32(18):2055-67.