"Deoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
| Descriptor ID |
D003840
|
| MeSH Number(s) |
D04.210.500.105.225.272 D04.210.500.221.430.342
|
| Concept/Terms |
Deoxycholic Acid- Deoxycholic Acid
- Acid, Deoxycholic
- Desoxycholic Acid
- Acid, Desoxycholic
- Dihydroxycholanoic Acid
- Acid, Dihydroxycholanoic
|
Below are MeSH descriptors whose meaning is more general than "Deoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Deoxycholic Acid".
This graph shows the total number of publications written about "Deoxycholic Acid" by people in this website by year, and whether "Deoxycholic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2005 | 1 | 3 | 4 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxycholic Acid" by people in Profiles.
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Discovery of Self-Assembling Small Molecules as Vaccine Adjuvants. Angew Chem Int Ed Engl. 2021 01 11; 60(2):961-969.
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ATX-101 (Deoxycholic Acid Injection) Leads to Clinically Meaningful Improvement in Submental Fat: Final Data From CONTOUR. Dermatol Surg. 2020 05; 46(5):639-645.
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Clostridium scindens ATCC 35704: Integration of Nutritional Requirements, the Complete Genome Sequence, and Global Transcriptional Responses to Bile Acids. Appl Environ Microbiol. 2019 04 01; 85(7).
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Successful treatment of Candida osteoarticular infections with limited duration of antifungal therapy and orthopedic surgical intervention. Infect Dis (Lond). 2015 Mar; 47(3):144-9.
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Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis. 2014 Jun; 46(6):527-34.
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Invasive fungal infections in newborns and current management strategies. Expert Rev Anti Infect Ther. 2013 Jul; 11(7):709-21.
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Activation of NF-?B protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish. J Biol Chem. 2012 Nov 02; 287(45):37926-38.
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Comparison of 2 doses of liposomal amphotericin B and conventional amphotericin B deoxycholate for treatment of AIDS-associated acute cryptococcal meningitis: a randomized, double-blind clinical trial of efficacy and safety. Clin Infect Dis. 2010 Jul 15; 51(2):225-32.
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Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3):G559-66.
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Pharmacodynamic activity of amphotericin B deoxycholate is associated with peak plasma concentrations in a neutropenic murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2006 Feb; 50(2):469-73.