"Chenodeoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
| Descriptor ID |
D002635
|
| MeSH Number(s) |
D04.210.500.105.225.272.150 D04.210.500.221.430.342.300
|
| Concept/Terms |
Chenodeoxycholic Acid- Chenodeoxycholic Acid
- Acid, Chenodeoxycholic
- Chenique Acid
- Acid, Chenique
- Gallodesoxycholic Acid
- Acid, Gallodesoxycholic
- Henohol
- Chenic Acid
- Acid, Chenic
- Chenodiol
|
Below are MeSH descriptors whose meaning is more general than "Chenodeoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Chenodeoxycholic Acid".
This graph shows the total number of publications written about "Chenodeoxycholic Acid" by people in this website by year, and whether "Chenodeoxycholic Acid" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chenodeoxycholic Acid" by people in Profiles.
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Primary biliary cholangitis. Lancet. 2024 Sep 14; 404(10457):1053-1066.
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Structural, Biochemical, and In Vivo Characterization of MtrR-Mediated Resistance to Innate Antimicrobials by the Human Pathogen Neisseria gonorrhoeae. J Bacteriol. 2019 10 15; 201(20).
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The challenges of primary biliary cholangitis: What is new and what needs to be done. J Autoimmun. 2019 12; 105:102328.
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Apparent underdiagnosis of Cerebrotendinous Xanthomatosis revealed by analysis of ~60,000 human exomes. Mol Genet Metab. 2015 Dec; 116(4):298-304.
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Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis. 2014 Jun; 46(6):527-34.
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Enteral bile acid treatment improves parenteral nutrition-related liver disease and intestinal mucosal atrophy in neonatal pigs. Am J Physiol Gastrointest Liver Physiol. 2012 Jan 15; 302(2):G218-24.
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Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression. Oncogene. 2011 Sep 29; 30(39):4129-40.
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Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells. J Biol Chem. 2010 Feb 19; 285(8):5581-93.
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Bile acids inhibit NAD+-dependent 15-hydroxyprostaglandin dehydrogenase transcription in colonocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3):G559-66.
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Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer Res. 2008 Apr 15; 68(8):2632-40.