"Lithocholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.
| Descriptor ID |
D008095
|
| MeSH Number(s) |
D04.210.500.105.225.480 D04.210.500.221.430.622
|
| Concept/Terms |
Lithocholic Acid- Lithocholic Acid
- Acid, Lithocholic
- Isolithocholic Acid
- Acid, Isolithocholic
|
Below are MeSH descriptors whose meaning is more general than "Lithocholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Lithocholic Acid".
This graph shows the total number of publications written about "Lithocholic Acid" by people in this website by year, and whether "Lithocholic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lithocholic Acid" by people in Profiles.
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Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice. Toxicol Lett. 2014 Jul 03; 228(1):56-66.
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Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. Drug Metab Dispos. 2009 Jun; 37(6):1328-33.
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Site-directed mutational analysis of structural interactions of low molecule compounds binding to the N-terminal 8 kDa domain of DNA polymerase beta. Biochem Biophys Res Commun. 2006 Nov 10; 350(1):7-16.