"Cyclin G1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin G subtype that is constitutively expressed throughout the cell cycle. Cyclin G1 is considered a major transcriptional target of TUMOR SUPPRESSOR PROTEIN P53 and is highly induced in response to DNA damage.
| Descriptor ID |
D056766
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| MeSH Number(s) |
D12.644.360.262.200.100 D12.776.167.218.200.100 D12.776.476.262.200.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclin G1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin G1".
This graph shows the total number of publications written about "Cyclin G1" by people in this website by year, and whether "Cyclin G1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
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Below are the most recent publications written about "Cyclin G1" by people in Profiles.
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Cyclin G1 regulates the outcome of taxane-induced mitotic checkpoint arrest. Oncogene. 2012 May 10; 31(19):2450-60.
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Nuclear cyclin B1 is overexpressed in low-malignant-potential ovarian tumors but not in epithelial ovarian cancer. Am J Obstet Gynecol. 2009 Oct; 201(4):367.e1-6.
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MiR-122/cyclin G1 interaction modulates p53 activity and affects doxorubicin sensitivity of human hepatocarcinoma cells. Cancer Res. 2009 Jul 15; 69(14):5761-7.
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Cyclin degradation for cancer therapy and chemoprevention. J Cell Biochem. 2007 Nov 01; 102(4):869-77.
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Cyclin G1 is a target of miR-122a, a microRNA frequently down-regulated in human hepatocellular carcinoma. Cancer Res. 2007 Jul 01; 67(13):6092-9.
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Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy. Clin Cancer Res. 2004 Apr 01; 10(7):2570-7.
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Differential gene expression in mouse mammary adenocarcinomas in the presence and absence of wild type p53. Oncogene. 2000 Dec 07; 19(52):5988-96.
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Insulin-like growth factor-I extends in vitro replicative life span of skeletal muscle satellite cells by enhancing G1/S cell cycle progression via the activation of phosphatidylinositol 3'-kinase/Akt signaling pathway. J Biol Chem. 2000 Nov 17; 275(46):35942-52.
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G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts. Curr Biol. 1998 Jan 01; 8(1):65-8.