The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia.

The Dual Syk/JAK Inhibitor Cerdulatinib Antagonizes B-cell Receptor and Microenvironmental Signaling in Chronic Lymphocytic Leukemia. Clin Cancer Res. 2017 May 01; 23(9):2313-2324.

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subject areas

Adenine
Antineoplastic Combined Chemotherapy Protocols
Apoptosis
B-Lymphocytes
Bridged Bicyclo Compounds, Heterocyclic
Flow Cytometry
Gene Expression Regulation, Neoplastic
Humans
Janus Kinase Inhibitors
Janus Kinases
Leukemia, Lymphocytic, Chronic, B-Cell
Leukocytes, Mononuclear
Neoplasm Proteins
Piperidines
Proto-Oncogene Proteins c-bcr
Pyrazoles
Pyrimidines
Receptors, Antigen, B-Cell
Signal Transduction
Sulfonamides
Sulfones
Syk Kinase
Tumor Microenvironment

authors with profiles

JAN ANDREAS BURGER