Activating Transcription Factor 4
"Activating Transcription Factor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An activating transcription factor that regulates the expression of a variety of GENES involved in amino acid metabolism and transport. It also interacts with HTLV-I transactivator protein.
| Descriptor ID |
D051701
|
| MeSH Number(s) |
D12.776.260.108.061.937 D12.776.930.127.061.937
|
| Concept/Terms |
Activating Transcription Factor 4- Activating Transcription Factor 4
- ATF4 Transcription Factor
- Transcription Factor, ATF4
- Tax-Responsive Enhancer Element B67
- Tax Responsive Enhancer Element B67
|
Below are MeSH descriptors whose meaning is more general than "Activating Transcription Factor 4".
Below are MeSH descriptors whose meaning is more specific than "Activating Transcription Factor 4".
This graph shows the total number of publications written about "Activating Transcription Factor 4" by people in this website by year, and whether "Activating Transcription Factor 4" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 2 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 4 | 7 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Activating Transcription Factor 4" by people in Profiles.
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The ISR downstream target ATF4 represses long-term memory in a cell type-specific manner. Proc Natl Acad Sci U S A. 2024 Jul 30; 121(31):e2407472121.
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Thbs1 regulates skeletal muscle mass in a TGF?-Smad2/3-ATF4-dependent manner. Cell Rep. 2024 May 28; 43(5):114149.
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TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF. Int J Mol Sci. 2022 Dec 11; 23(24).
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Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a. PLoS Genet. 2021 12; 17(12):e1009934.
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Memory suppressor genes: Modulating acquisition, consolidation, and forgetting. Neuron. 2021 10 20; 109(20):3211-3227.
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Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex. J Nutr. 2021 04 08; 151(4):785-799.
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Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast-like Cells Is Driven by an Unfolded Protein Response. Arterioscler Thromb Vasc Biol. 2021 01; 41(1):302-316.
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Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation. Blood Adv. 2019 12 23; 3(24):4215-4227.
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Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer. Oncogene. 2019 08; 38(35):6301-6318.
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Regulation of H2A ubiquitination and SLC7A11 expression by BAP1 and PRC1. Cell Cycle. 2019 04; 18(8):773-783.