Receptor, Melanocortin, Type 4
"Receptor, Melanocortin, Type 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH and ADRENOCORTICOTROPIC HORMONE.
| Descriptor ID |
D044105
|
| MeSH Number(s) |
D12.776.543.750.695.430.937 D12.776.543.750.720.600.285.500.937 D12.776.543.750.750.555.285.500.937 D12.776.543.750.750.660.285.500.937
|
| Concept/Terms |
Receptor, Melanocortin, Type 4- Receptor, Melanocortin, Type 4
- Melanocortin Receptor 4
- Receptor 4, Melanocortin
- Receptor, Melanocortin-4
- Melanocortin 4 Receptor
- Receptor, Melanocortin 4
- Melanocortin-4 Receptor
- MC4 Receptor
- Receptor, MC4
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Melanocortin, Type 4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Melanocortin [D12.776.543.750.695.430]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.695.430.937]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin [D12.776.543.750.720.600.285]
- Receptors, Melanocortin [D12.776.543.750.720.600.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.720.600.285.500.937]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin [D12.776.543.750.750.555.285]
- Receptors, Melanocortin [D12.776.543.750.750.555.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.555.285.500.937]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Corticotropin [D12.776.543.750.750.660.285]
- Receptors, Melanocortin [D12.776.543.750.750.660.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.660.285.500.937]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Melanocortin, Type 4".
This graph shows the total number of publications written about "Receptor, Melanocortin, Type 4" by people in this website by year, and whether "Receptor, Melanocortin, Type 4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 2 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Receptor, Melanocortin, Type 4" by people in Profiles.
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Investigation of setmelanotide, an MC4R agonist, for obesity in individuals with Smith-Magenis syndrome. Obes Res Clin Pract. 2024 Jul-Aug; 18(4):301-307.
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Therapeutic Strategies Against Metabolic Imbalance in a Male Mouse Model With 5-HT2CR Loss-of-Function. Endocrinology. 2024 May 27; 165(7).
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The melanocortin action is biased toward protection from weight loss in mice. Nat Commun. 2023 04 17; 14(1):2200.
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Deciphering an AgRP-serotoninergic neural circuit in distinct control of energy metabolism from feeding. Nat Commun. 2021 06 10; 12(1):3525.
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A Targeted Next Generation Sequencing Panel for Non-syndromic Early Onset Severe Obesity and Identification of Novel Likely -Pathogenic Variants in the MC4R and LEP Genes. Indian J Pediatr. 2020 02; 87(2):105-110.
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Melanocortin 4 receptor is not required for estrogenic regulations on energy homeostasis and reproduction. Metabolism. 2017 05; 70:152-159.
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Common variants in the obesity-associated genes FTO and MC4R are not associated with risk of colorectal cancer. Cancer Epidemiol. 2016 10; 44:1-4.
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Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium. Int J Epidemiol. 2015 Apr; 44(2):638-50.
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Profound and rapid reduction in body temperature induced by the melanocortin receptor agonists. Biochem Biophys Res Commun. 2014 Aug 22; 451(2):184-9.
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Biphasic effect of melanocortin agonists on metabolic rate and body temperature. Cell Metab. 2014 Aug 05; 20(2):333-45.