Receptor, Melanocortin, Type 1
"Receptor, Melanocortin, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A melanocortin receptor subtype found primarily in MELANOCYTES. It shows specificity for ALPHA-MSH and ADRENOCORTICOTROPIC HORMONE. Loss of function mutations of the type 1 melanocortin receptor account for the majority of red hair and fair skin recessive traits in human.
| Descriptor ID |
D044102
|
| MeSH Number(s) |
D12.776.543.750.695.430.500 D12.776.543.750.720.600.285.500.500 D12.776.543.750.750.555.285.500.500 D12.776.543.750.750.660.285.500.500
|
| Concept/Terms |
Receptor, Melanocortin, Type 1- Receptor, Melanocortin, Type 1
- Receptor, Melanocortin-1
- Receptor, Melanocortin 1
- Melanocortin Receptor 1
- Receptor 1, Melanocortin
- Melanocyte Melanocortin Receptor
- Melanocortin Receptor, Melanocyte
- Receptor, Melanocyte Melanocortin
- MC1 Receptor
- Receptor, MC1
- Melanocortin-1 Receptor
- Melanocortin 1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Melanocortin, Type 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Melanocortin [D12.776.543.750.695.430]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.695.430.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin [D12.776.543.750.720.600.285]
- Receptors, Melanocortin [D12.776.543.750.720.600.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.720.600.285.500.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin [D12.776.543.750.750.555.285]
- Receptors, Melanocortin [D12.776.543.750.750.555.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.750.555.285.500.500]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Corticotropin [D12.776.543.750.750.660.285]
- Receptors, Melanocortin [D12.776.543.750.750.660.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.750.660.285.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Melanocortin, Type 1".
This graph shows the total number of publications written about "Receptor, Melanocortin, Type 1" by people in this website by year, and whether "Receptor, Melanocortin, Type 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Receptor, Melanocortin, Type 1" by people in Profiles.
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Direct migration of follicular melanocyte stem cells to the epidermis after wounding or UVB irradiation is dependent on Mc1r signaling. Nat Med. 2013 Jul; 19(7):924-9.
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Variants in melanocortin 1 receptor gene contribute to risk of melanoma--a direct sequencing analysis in a Texas population. Pigment Cell Melanoma Res. 2013 May; 26(3):422-5.
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An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature. 2012 Nov 15; 491(7424):449-53.
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Receptor-mediated transcytosis: a mechanism for active extravascular transport of nanoparticles in solid tumors. J Control Release. 2012 Aug 10; 161(3):959-66.
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Network topology determines dynamics of the mammalian MAPK1,2 signaling network: bifan motif regulation of C-Raf and B-Raf isoforms by FGFR and MC1R. FASEB J. 2008 May; 22(5):1393-403.
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Accumulation of low-avidity anti-melanocortin receptor 1 (anti-MC1R) CD8+ T cells in the lesional skin of a patient with melanoma-related depigmentation. Melanoma Res. 2006 Apr; 16(2):165-74.