"Okadaic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
| Descriptor ID |
D019319
|
| MeSH Number(s) |
D02.355.291.705
|
| Concept/Terms |
Okadaic Acid- Okadaic Acid
- Acid, Okadaic
- Ocadaic Acid
- Acid, Ocadaic
|
Below are MeSH descriptors whose meaning is more general than "Okadaic Acid".
Below are MeSH descriptors whose meaning is more specific than "Okadaic Acid".
This graph shows the total number of publications written about "Okadaic Acid" by people in this website by year, and whether "Okadaic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Okadaic Acid" by people in Profiles.
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Revisiting the multisite phosphorylation that produces the M-phase supershift of key mitotic regulators. Mol Biol Cell. 2022 10 01; 33(12):ar115.
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Selective elimination of human pluripotent stem cells by a marine natural product derivative. J Am Chem Soc. 2014 Jul 16; 136(28):9798-801.
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Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway. PLoS One. 2010 May 11; 5(5):e10578.
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Phosphorylation of PDZ1 domain attenuates NHERF-1 binding to cellular targets. J Biol Chem. 2007 Nov 16; 282(46):33879-33887.
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Down-regulation of ERK but not MEK phosphorylation in cultured endothelial cells by repeated changes in cyclic stretch. Cardiovasc Res. 2007 Mar 01; 73(4):813-22.
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Conditional knockout mice reveal an essential role of protein phosphatase 4 in thymocyte development and pre-T-cell receptor signaling. Mol Cell Biol. 2007 Jan; 27(1):79-91.
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An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9673-8.
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Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes. Biochem Biophys Res Commun. 2006 Aug 04; 346(3):700-6.
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Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation. J Biol Chem. 2006 Mar 03; 281(9):5612-22.
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Protein phosphatase 4 interacts with and down-regulates insulin receptor substrate 4 following tumor necrosis factor-alpha stimulation. J Biol Chem. 2004 Nov 05; 279(45):46588-94.