"Poly A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of adenine ribonucleotides in which the phosphate residues of each adenine ribonucleotide act as bridges in forming diester linkages between the ribose moieties.
| Descriptor ID |
D011061
|
| MeSH Number(s) |
D13.695.578.550.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Poly A".
Below are MeSH descriptors whose meaning is more specific than "Poly A".
This graph shows the total number of publications written about "Poly A" by people in this website by year, and whether "Poly A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 2 | 1 | 3 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 2 | 2 |
| 2021 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Poly A" by people in Profiles.
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Control of mammalian gene expression by modulation of polyA signal cleavage at 5' UTR. Nat Biotechnol. 2024 Sep; 42(9):1454-1466.
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A computational pipeline to infer alternative poly-adenylation from 3' sequencing data. Methods Enzymol. 2021; 655:185-204.
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Application and design considerations for 3'-end sequencing using click-chemistry. Methods Enzymol. 2021; 655:1-23.
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Identification of Circular RNAs by Multiple Displacement Amplification and Their Involvement in Plant Development. Methods Mol Biol. 2021; 2362:69-91.
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Structures of mammalian GLD-2 proteins reveal molecular basis of their functional diversity in mRNA and microRNA processing. Nucleic Acids Res. 2020 09 04; 48(15):8782-8795.
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Purification of poly-dA oligonucleotides and mRNA-protein fusions with dT25-OAS resin. Bioorg Med Chem Lett. 2020 02 15; 30(4):126934.
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The Canonical Poly (A) Polymerase PAP1 Polyadenylates Non-Coding RNAs and Is Essential for snoRNA Biogenesis in Trypanosoma brucei. J Mol Biol. 2017 10 27; 429(21):3301-3318.
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Genome Therapy of Myotonic Dystrophy Type 1 iPS Cells for Development of Autologous Stem Cell Therapy. Mol Ther. 2016 08; 24(8):1378-87.
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CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function. RNA. 2016 06; 22(6):830-8.
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CD5 expression is regulated during human T-cell activation by alternative polyadenylation, PTBP1, and miR-204. Eur J Immunol. 2016 06; 46(6):1490-503.