3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
"3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 3-hydroxysteroid dehydrogenase which catalyzes the reversible reduction of the active androgen, DIHYDROTESTOSTERONE to 5 ALPHA-ANDROSTANE-3 ALPHA,17 BETA-DIOL. It also has activity towards other 3-alpha-hydroxysteroids and on 9-, 11- and 15- hydroxyprostaglandins. The enzyme is B-specific in reference to the orientation of reduced NAD or NADPH.
| Descriptor ID |
D045002
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| MeSH Number(s) |
D08.811.682.047.436.350.100 D08.811.682.047.820.186
|
| Concept/Terms |
3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)- 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)
- 3alpha-Hydroxysteroid Dehydrogenase (B-specific)
- 3 alpha-Hydroxysteroid Oxidoreductase
- 3 alpha Hydroxysteroid Oxidoreductase
- Oxidoreductase, 3 alpha-Hydroxysteroid
- 3 alpha-Hydroxysteroid Dehydrogenase
- 3 alpha Hydroxysteroid Dehydrogenase
- Dehydrogenase, 3 alpha-Hydroxysteroid
- 3 alpha-Hydroxysteroid Dehydrogenase (B-Specific)
5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase- 5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase
- 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase
- 5-DP-3 alpha-HSO
- NADPH-5 alpha-Dihydroprogesterone 3 alpha-Hydroxysteroid Oxidoreductase
- NADPH 5 alpha Dihydroprogesterone 3 alpha Hydroxysteroid Oxidoreductase
- 5 alpha-3 alpha-Hydroxysteroid Dehydrogenase
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Below are MeSH descriptors whose meaning is more general than "3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)".
Below are MeSH descriptors whose meaning is more specific than "3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)".
This graph shows the total number of publications written about "3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)" by people in this website by year, and whether "3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
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Below are the most recent publications written about "3-alpha-Hydroxysteroid Dehydrogenase (B-Specific)" by people in Profiles.
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Removal of the bile acid pool upregulates cholesterol 7alpha-hydroxylase by deactivating FXR in rabbits. J Lipid Res. 2002 Jan; 43(1):45-50.
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Cholecystectomy prevents expansion of the bile acid pool and inhibition of cholesterol 7alpha-hydroxylase in rabbits fed cholesterol. J Lipid Res. 2001 Sep; 42(9):1438-43.
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Ileal bile acid transport regulates bile acid pool, synthesis, and plasma cholesterol levels differently in cholesterol-fed rats and rabbits. J Lipid Res. 2000 Feb; 41(2):298-304.
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Genetic cholestasis syndromes. J Pediatr Gastroenterol Nutr. 1999 Feb; 28(2):124-31.
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Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter. Hepatology. 1998 Oct; 28(4):1081-7.
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A new era in bile acid transport pathophysiology. J Pediatr Gastroenterol Nutr. 1998 Feb; 26(2):236-7.
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Glucocorticoids upregulate taurocholate transport by ileal brush-border membrane. Am J Physiol. 1997 Jul; 273(1 Pt 1):G197-203.
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Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J Clin Invest. 1995 Feb; 95(2):745-54.