Ubiquitin-Conjugating Enzymes
"Ubiquitin-Conjugating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044763
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| MeSH Number(s) |
D08.811.464.938.500
|
| Concept/Terms |
Ubiquitin-Conjugating Enzymes- Ubiquitin-Conjugating Enzymes
- Enzymes, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzymes
- Ubiquitin-Conjugating Enzyme E2
- E2, Ubiquitin-Conjugating Enzyme
- Enzyme E2, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzyme E2
|
Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Conjugating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Conjugating Enzymes".
This graph shows the total number of publications written about "Ubiquitin-Conjugating Enzymes" by people in this website by year, and whether "Ubiquitin-Conjugating Enzymes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 1 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 4 | 6 |
| 2009 | 2 | 3 | 5 |
| 2010 | 0 | 1 | 1 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 3 | 2 | 5 |
| 2015 | 3 | 1 | 4 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Ubiquitin-Conjugating Enzymes" by people in Profiles.
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Development of a BCL-xL and BCL-2 dual degrader with improved anti-leukemic activity. Nat Commun. 2021 11 25; 12(1):6896.
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Ube2i deletion in adipocytes causes lipoatrophy in mice. Mol Metab. 2021 06; 48:101221.
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Refinement of the clinical and mutational spectrum of UBE2A deficiency syndrome. Clin Genet. 2020 08; 98(2):172-178.
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Loss of the E2 SUMO-conjugating enzyme Ube2i in oocytes during ovarian folliculogenesis causes infertility in mice. Development. 2019 12 02; 146(23).
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The DNA repair protein SHPRH is a nucleosome-stimulated ATPase and a nucleosome-E3 ubiquitin ligase. Epigenetics Chromatin. 2019 08 21; 12(1):52.
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A muscle-specific UBE2O/AMPKa2 axis promotes insulin resistance and metabolic syndrome in obesity. JCI Insight. 2019 07 11; 4(13).
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Epstein-Barr Virus Latent Membrane Protein-1 Induces the Expression of SUMO-1 and SUMO-2/3 in LMP1-positive Lymphomas and Cells. Sci Rep. 2019 01 18; 9(1):208.
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SUMOylation of ROR-?t inhibits IL-17 expression and inflammation via HDAC2. Nat Commun. 2018 10 30; 9(1):4515.
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Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):E2311-E2319.
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Radiosensitization by inhibiting DNA repair: Turning the spotlight on homologous recombination. Hepatology. 2018 02; 67(2):470-472.