"rac1 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rac GTP-binding protein involved in regulating actin filaments at the plasma membrane. It controls the development of filopodia and lamellipodia in cells and thereby influences cellular motility and adhesion. It is also involved in activation of NADPH OXIDASES. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020830
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.700.100.500 D12.644.360.525.700.100.100 D12.776.157.325.515.700.100.100 D12.776.476.525.700.100.100
|
| Concept/Terms |
rac1 GTP-Binding Protein- rac1 GTP-Binding Protein
- GTP-Binding Protein, rac1
- rac1 GTP Binding Protein
- rac1 Protein
- TC-25 GTP-Binding Protein
- GTP-Binding Protein, TC-25
- TC 25 GTP Binding Protein
- ras-Related C3 Botulinum Toxin Substrate 1
- ras Related C3 Botulinum Toxin Substrate 1
|
Below are MeSH descriptors whose meaning is more general than "rac1 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rac1 GTP-Binding Protein".
This graph shows the total number of publications written about "rac1 GTP-Binding Protein" by people in this website by year, and whether "rac1 GTP-Binding Protein" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 1 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 3 | 2 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 0 | 3 | 3 |
| 2007 | 3 | 2 | 5 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 3 | 5 |
| 2010 | 0 | 4 | 4 |
| 2011 | 1 | 3 | 4 |
| 2012 | 2 | 4 | 6 |
| 2013 | 4 | 2 | 6 |
| 2014 | 5 | 2 | 7 |
| 2015 | 2 | 4 | 6 |
| 2016 | 2 | 1 | 3 |
| 2017 | 2 | 3 | 5 |
| 2018 | 1 | 2 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "rac1 GTP-Binding Protein" by people in Profiles.
-
Tiam1-mediated maladaptive plasticity underlying morphine tolerance and hyperalgesia. Brain. 2024 Jul 05; 147(7):2507-2521.
-
A distinct pattern of growth and RAC1 signaling in melanoma brain metastasis cells. Neuro Oncol. 2023 04 06; 25(4):674-686.
-
Mechanical Stress Signaling in Pancreatic Cancer Cells Triggers p38 MAPK- and JNK-Dependent Cytoskeleton Remodeling and Promotes Cell Migration via Rac1/cdc42/Myosin II. Mol Cancer Res. 2022 Mar 01; 20(3):485-497.
-
Daam2 Regulates Myelin Structure and the Oligodendrocyte Actin Cytoskeleton through Rac1 and Gelsolin. J Neurosci. 2022 03 02; 42(9):1679-1691.
-
Ontogeny and function of the circadian clock in intestinal organoids. EMBO J. 2022 12 17; 41(2):e106973.
-
Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway. Oxid Med Cell Longev. 2021; 2021:5550498.
-
Daam2 couples translocation and clustering of Wnt receptor signalosomes through Rac1. J Cell Sci. 2021 01 25; 134(2).
-
Knockdown of RhoGDI2 represses human gastric cancer cell proliferation, invasion and drug resistance via the Rac1/Pak1/LIMK1 pathway. Cancer Lett. 2020 11 01; 492:136-146.
-
The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling. J Neurosci. 2018 09 26; 38(39):8388-8406.
-
Diallyl disulfide inhibits TGF-?1-induced upregulation of Rac1 and ?-catenin in epithelial-mesenchymal transition and tumor growth of gastric cancer. Oncol Rep. 2018 Jun; 39(6):2797-2806.