"Choline Deficiency" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A condition produced by a deficiency of CHOLINE in animals. Choline is known as a lipotropic agent because it has been shown to promote the transport of excess fat from the liver under certain conditions in laboratory animals. Combined deficiency of choline (included in the B vitamin complex) and all other methyl group donors causes liver cirrhosis in some animals. Unlike compounds normally considered as vitamins, choline does not serve as a cofactor in enzymatic reactions. (From Saunders Dictionary & Encyclopedia of Laboratory Medicine and Technology, 1984)
| Descriptor ID |
D002796
|
| MeSH Number(s) |
C18.654.521.500.133.699.160
|
| Concept/Terms |
Choline Deficiency- Choline Deficiency
- Deficiency, Choline
- Choline Deficiencies
- Deficiencies, Choline
|
Below are MeSH descriptors whose meaning is more general than "Choline Deficiency".
Below are MeSH descriptors whose meaning is more specific than "Choline Deficiency".
This graph shows the total number of publications written about "Choline Deficiency" by people in this website by year, and whether "Choline Deficiency" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Choline Deficiency" by people in Profiles.
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Choline. Adv Nutr. 2018 01 01; 9(1):58-60.
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Fatty acids in non-alcoholic steatohepatitis: Focus on pentadecanoic acid. PLoS One. 2017; 12(12):e0189965.
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Common Genetic Variants Alter Metabolism and Influence Dietary Choline Requirements. Nutrients. 2017 Aug 04; 9(8).
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Clonal tracing of Sox9+ liver progenitors in mouse oval cell injury. Hepatology. 2014 Jul; 60(1):278-89.
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Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury. J Proteomics. 2012 Oct 22; 75(18):5783-92.
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Choline intake in a large cohort of patients with nonalcoholic fatty liver disease. Am J Clin Nutr. 2012 Apr; 95(4):892-900.
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Oral choline supplementation in children with intestinal failure. J Pediatr Gastroenterol Nutr. 2011 Jul; 53(1):115-9.
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Changes in plasma free and phospholipid-bound choline concentrations in chronic hemodialysis patients. J Ren Nutr. 2000 Jul; 10(3):133-8.
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Liver carcinogenesis associated with feeding of ethionine in a choline-free diet: evidence against a role of oval cells in the emergence of hepatocellular carcinoma. Hepatology. 1993 Sep; 18(3):596-603.
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Persistent reduction of indigenous DNA modification (I-compound) levels in liver DNA from male Fischer rats fed choline-devoid diet and in DNA of resulting neoplasms. Cancer Res. 1990 Dec 01; 50(23):7577-80.